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Testosterone propionate

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Identification
Molecular formula
C22H32O3
CAS number
57-85-2
IUPAC name
[(8R,9S,13S,14S,17S)-13-methyl-3-propanoyloxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] propanoate
State
State

Testosterone propionate is typically found in a solid crystalline form at room temperature.

Melting point (Celsius)
125.00
Melting point (Kelvin)
398.15
Boiling point (Celsius)
440.00
Boiling point (Kelvin)
713.15
General information
Molecular weight
344.50g/mol
Molar mass
344.4860g/mol
Density
1.0595g/cm3
Appearence

Testosterone propionate appears as a white or white crystalline powder. It is typically odorless and can vary slightly in color from completely white to slightly off-white.

Comment on solubility

Solubility of [(8R,9S,13S,14S,17S)-13-methyl-3-propanoyloxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] propanoate

The solubility characteristics of the compound [(8R,9S,13S,14S,17S)-13-methyl-3-propanoyloxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] propanoate can be quite complex due to its intricate structure and the presence of multiple functional groups. Generally, solubility can be influenced by several factors:

  • Polarity: This compound possesses both hydrophobic and hydrophilic regions, which can affect its solubility in water. Typically, non-polar compounds have low solubility in polar solvents like water.
  • Temperature: As with many organic compounds, solubility often increases with temperature. Therefore, heating the solvent may enhance the dissolution process.
  • Solvent Choice: It is likely to exhibit better solubility in organic solvents such as ethanol, acetone, or chloroform, which can stabilize the compound’s non-polar characteristics.
  • Concentration: The solubility may vary significantly based on the concentration of the compound in the solvent, leading to phenomena like supersaturation.

Understanding the solubility of this compound is crucial for its application in various fields, particularly in pharmaceuticals where solubility directly impacts bioavailability and therapeutic effectiveness. Detailed experiments may be required to elucidate precise solubility values under specific conditions, providing a clearer understanding of its behavior in different solvents.

Interesting facts

Interesting Facts about [(8R,9S,13S,14S,17S)-13-methyl-3-propanoyloxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] propanoate

This compound is a fascinating example of the diverse structures found within organic chemistry. Its complex stereochemistry is highlighted by the designation of multiple stereocenters, which plays a significant role in determining its biological activity. Here are some intriguing points about this compound:

  • Stereoactivity: The specific stereochemistry (noted by its R and S configurations) can dramatically affect the compound’s interactions with biological systems, making it an important topic of study in medicinal chemistry.
  • Biological Relevance: Compounds with similar structures have been studied for their potential pharmaceutical applications, highlighting the significance of understanding how subtle structural changes can influence biological activity.
  • Mechanism of Action: Research often explores how such complex molecules interact at the molecular level, including receptor binding, and their subsequent biological response, which is crucial for drug design.
  • Synthetic Pathways: The synthesis of this compound can involve multiple steps, showcasing the ingenuity of organic chemists in constructing complex molecules from simpler precursors.

As noted by one prominent chemist, "Understanding the intricate design of these molecular structures not only reveals the beauty of chemistry but also paves the way for new discoveries in the field of therapeutics."

This compound serves as a vivid reminder of the rich tapestry of organic chemistry, emphasizing both the creative and practical aspects of the discipline.

Synonyms
estradiol dipropionate
113-38-2
Diprostron
Agofollin
Diovocylin
Progynon-DP
Akrofolline
Diovocyclin
Dimenformon dipropionate
Estroici
Estronex
Nacyclyl
Follicyclin P
Ovocyclin-P
Ovocyclin dipropionate
Oestradiol dipropionate
Oestradiol Streuli
Agofollin [inj.]
Oestradioli propionas
Endofollicolina D.P.
Estradiol 3,17-dipropionate
Oestradiol-3,17-dipropionate
Dipropionate D'oestradiol
3,17beta-Estradiol dipropionate
beta-Estradiol dipropionate
CCRIS 282
Estradiol dipropionate [JAN]
17-beta-Estradiol dipropionate
17-beta-Oestradiol dipropionate
3,17-beta-Oestradiol dipropionate
Dipropionate d'oestradiol [French]
EINECS 204-026-5
NIG5418BXB
BRN 3223915
DTXSID8023000
1,3,5(10)-Estratriene-3,17beta-diol dipropionate
Estradiol dipropionate [JAN:NF]
(17beta)-Estra-1,3,5(10)-triene-3,17-diol, dipropanoate
Estradiol dipropionate (JAN)
DTXCID303000
CHEBI:31560
Estra-1,3,5(10)-triene-3,17-diol (17-beta)-dipropionate
ESTRADIOL DIPROPIONATE [MI]
4-06-00-06613 (Beilstein Handbook Reference)
Agofollin (inj.)
ESTRADIOL DIPROPIONATE [MART.]
ESTRADIOL DIPROPIONATE [WHO-DD]
3,17-dipropionyl-estra-1,3,5(10)-triene-3,17beta-diol
[(8R,9S,13S,14S,17S)-13-methyl-3-propanoyloxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] propanoate
(17beta)-estra-1(10),2,4-triene-3,17-diyl dipropanoate
ESTRADIOL DIPROPIONATE (MART.)
UNII-NIG5418BXB
Ovahormon depot
NCGC00159328-02
Estradiol Dipropionate; [(8R,9S,13S,14S,17S)-13-Methyl-17-propanoyloxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] propanoate; 17-beta-Estradiol 3,17-dipropionate
MFCD00051146
17-Beta-Estradiol-3,17-Dipropionate
17-|A-ESTRADIOL 3,17-DIPROPIONATE
.beta.-Estradiol dipropionate
SCHEMBL348106
.beta.-Oestradiol dipropionate
Estra-1,3,5(10)-triene-3,17-diol (17.beta.)-, dipropanoate
CHEMBL1697791
17-.beta.-Estradiol dipropionate
(17 beta)-estra-1,3,5(10)-triene-3,17-diol, dipropanoate
17-.beta.-Oestradiol dipropionate
HY-B2245
Tox21_113111
.beta.-Estradiol 3,17-dipropionate
17beta-Estradiol 3,17-Dipropionate
3,17-.beta.-Estradiol dipropionate
LMST02010040
s5872
3,17-.beta.-Oestradiol dipropionate
AKOS025311445
FE33819
17.beta.-Estradiol 3,17-dipropionate
AS-12946
CAS-113-38-2
CS-0030371
E1344
NS00023682
D01617
T71607
SR-01000884017
Q5401761
SR-01000884017-1
1,3,5(10)-Estratriene-3,17.beta.-diol dipropionate
(17beta)Estra-1,3,5(10)triene-3,17-diol dipropanoate
(17beta)-Estra-1,3,5(10)-triene-3,17-diol Dipropanoate
17-(Propionyloxy)estra-1(10),2,4-trien-3-yl propionate #
3,17beta-Dihydroxy-1,3,5(10)-estratriene 3,17-dipropionate
Estra-1,3,5(10)-triene-3,17-diol (17.beta.), dipropionate
Estra-1,3,5(10)-triene-3,17-diol (17.beta.)-dipropanoate
(17.beta.)-Estra-1,3,5(10)-triene-3,17-diol 3,17-dipropionate
beta-Estradiol 3,17-dipropionate, VETRANAL(TM), analytical standard
Estradiol 3,17-dipropionate;beta-Estradiol dipropionate;Progynon DP;Ovocyclin dipropionate
204-026-5