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Testosterone benzoate

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Identification
Molecular formula
C26H34O3
CAS number
5823-08-9
IUPAC name
[(8R,9S,13S,14S,17R)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] benzoate
State
State

At room temperature, testosterone benzoate is typically a solid. It is stable under ordinary conditions of use and storage, often maintained in the solid form for pharmaceutical applications.

Melting point (Celsius)
196.00
Melting point (Kelvin)
469.15
Boiling point (Celsius)
515.50
Boiling point (Kelvin)
788.65
General information
Molecular weight
360.51g/mol
Molar mass
360.5080g/mol
Density
1.1300g/cm3
Appearence

Testosterone benzoate appears as a white crystalline powder. It is visually characterized by its powdery consistency and white color, which is typical for many steroid esters used in clinical applications and research.

Comment on solubility

Solubility of [(8R,9S,13S,14S,17R)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] benzoate

The solubility of the compound with the formula C26H34O3 can be quite intriguing. This complex structure indicates potential variations in solubility based on several factors:

  • Solvent Polarity: As a general principle, like dissolves like. A compound with both hydrophobic and hydrophilic regions may exhibit different solubility in polar vs. non-polar solvents.
  • Temperature: Increased temperature often enhances the solubility of solid compounds in liquids, making them more versatile in application.
  • pH Levels: The solubility of certain compounds can vary significantly with pH, especially for those containing functional groups that can ionize.

This particular compound, featuring a benzoate group, may be expected to be more soluble in organic solvents due to its hydrophobic characteristics. However, it might show limited solubility in water due to the lack of strong ionic or polar interactions.

In conclusion, understanding the solubility behavior requires careful consideration of the compound's structure, the properties of the solvent, and the environmental conditions. As noted, "the context of solubility is as essential as the compound itself," shaping its potential applications and interactions.

Interesting facts

Interesting Facts about [(8R,9S,13S,14S,17R)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] benzoate

This compound represents a fascinating class of chemicals known as steroids, specifically a derivative of a steroid molecule. Steroids play a critical role in biological systems, often functioning as hormones that regulate a variety of physiological processes. Here are some engaging highlights:

  • Structure and Function: The complex stereochemistry of this compound, indicated by its multiple chiral centers, suggests that its three-dimensional shape is essential for its biological activity. In many cases, the chirality of a molecule can significantly influence its interaction with biological receptors.
  • Uses in Medicine: Compounds similar to this one are frequently explored for their medicinal properties. They can act as anti-inflammatory agents, potential treatments for various diseases, and even as anabolic agents in sports.
  • Source of Inspiration: Such compounds are often derived from natural sources like plants and animals, inspiring scientists to synthesize derivatives that may enhance desired effects while minimizing side effects.
  • Research Significance: As research on hormonal pathways and steroid functions continues, compounds of this nature are invaluable to chemists and biochemists seeking to unlock new therapeutic avenues.
  • Analytical Techniques: Analyzing the properties of this compound can involve advanced techniques such as NMR spectroscopy and mass spectrometry, helping scientists thoroughly explore its structure and function.

In summary, [(8R,9S,13S,14S,17R)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] benzoate is not just a chemical entity; it holds potential that could lead to significant advancements in medical science and therapeutic applications.

Synonyms
alpha-Estradiol 3-benzoate
6045-53-0
Estra-1,3,5(10)-triene-3,17alpha-diol 3-benzoate
UNII-EB090UC9W9
EB090UC9W9
17.alpha.-Estradiol, 3-benzoate
EINECS 227-938-5
DTXSID90858951
.ALPHA.-ESTRADIOL 3-BENZOATE
[(8R,9S,13S,14S,17R)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] benzoate
a-Estradiol 3-Benzoate
Estra-1,3,5(10)-triene-3,17-diol, 3-benzoate, (17.alpha.)-
ESTRADIOL BENZOATE IMPURITY E [EP IMPURITY]
3-BENZOYLOXY-17.ALPHA.-HYDROXYOESTRA-1,3,5(10)-TRIENE
17alpha-Hydroxyestra-1,3,5(10)-trien-3-yl Benzoate (17-epi-Estradiol Benzoate)
ESTRADIOL BENZOATE IMPURITY E (EP IMPURITY)
17alpha-Hydroxyestra-1,3,5(10)-trien-3-yl Benzoate; Estradiol Benzoate Imp. E (EP); 17-epi-Estradiol Benzoate; Estradiol Benzoate Impurity E
SCHEMBL301616
DTXCID501324365
AKOS025402169
17ALPHA-ESTRADIOL, 3-BENZOATE
AC-6013
NS00081191
Q27277079
3-BENZOYLOXY-17ALPHA-HYDROXYOESTRA-1,3,5(10)-TRIENE
ESTRA-1,3,5(10)-TRIENE-3,17-DIOL, 3-BENZOATE, (17ALPHA)-
227-938-5