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Testosterone propionate

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Identification
Molecular formula
C22H32O3
CAS number
57-85-2
IUPAC name
[(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] propanoate
State
State

At room temperature, testosterone propionate is in a solid state, presenting as a crystalline powder. It is typically used in an oil-based solution for pharmaceutical purposes, especially in making testosterone injections.

Melting point (Celsius)
118.00
Melting point (Kelvin)
391.15
Boiling point (Celsius)
245.00
Boiling point (Kelvin)
518.15
General information
Molecular weight
344.49g/mol
Molar mass
344.4880g/mol
Density
1.1205g/cm3
Appearence

Testosterone propionate is a white or off-white crystalline powder. It is a synthetic androgen, structured as an ester of testosterone. The compound is usually stable and has low solubility in water, but dissolves readily in alcohol, oil, and chloroform.

Comment on solubility

Solubility of [(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] propanoate (C22H32O3)

This complex organic compound, characterized by its unique stereochemistry, demonstrates specific solubility properties influenced by its molecular structure. The solubility of C22H32O3 can be outlined as follows:

  • Solvent Compatibility: It is expected to be soluble in organic solvents such as ethanol, chloroform, and acetone due to the presence of both lipophilic and hydrophilic components in its structure.
  • Alkane Solubility: Given its hydrocarbon backbone, it may also dissolve well in non-polar solvents, affirming its hydrophobic nature.
  • Water Solubility: However, due to the large hydrophobic domain, solubility in water is likely to be very low, if not negligible.

It’s important to note that solubility can vary significantly based on temperature and other environmental factors. When discussing such compounds, one might say, “It’s all about the balance of polar and non-polar interactions!” In a laboratory setting, conducting solubility tests in various solvent systems can provide crucial insights into the practical handling and application of this compound.

Interesting facts

Interesting Facts about [(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] propanoate

This intriguing compound, typically associated with the steroid class of molecules, presents numerous fascinating aspects worth discussing. Here are some key points:

  • Structural Complexity: The compound exhibits a highly intricate structure characterized by multiple stereocenters and a bicyclic arrangement, showcasing the diverse nature of natural products.
  • Biological Relevance: Compounds of this type often play critical roles in biological systems. They may function as hormones, signaling molecules, or precursors to various steroid hormones, impacting a wide range of physiological processes.
  • Synthesis Challenge: The synthesis of this molecule can be quite complex, typically involving several steps of reactions such as oxidation, reduction, and cyclization to achieve the desired stereoisomeric form.
  • Pharmaceutical Importance: As a derivative of steroids, it could potentially lead to the development of new therapeutic agents in the pharmaceutical realm, especially in the treatment of conditions like hormone imbalance or specific types of cancer.
  • Environmental Considerations: Many steroid compounds, including this one, must be assessed for their environmental impact, particularly when considering their metabolic pathways and degradation processes in ecological systems.

As chemists continue to explore the potential applications and effects of this compound, it opens up avenues for advanced research in fields such as medicinal chemistry, biochemistry, and pharmacology. The quote from the American Chemical Society perfectly encapsulates this exploration: "Chemistry is the central science."

Whether studying its unique properties or devising synthetic routes, the complex structure of this compound promises to reveal much about the intersection of chemistry and the biological sciences.

Synonyms
testosterone propionate
57-85-2
Agovirin
Androlon
Androteston
Aquaviron
Hormoteston
Enarmon
Bio-testiculina
Androtest P
Androsteston
Masenate
Orchistin
Pantestin
Propiokan
Solvotest
Sterandryl
Synandrol
Synerone
Testaform
Testodet
Testodrin
Testogen
Testolets
Testonique
Testormol
Testosid
Testoxyl
Uniteston
Nasdol
Orchiol
Telipex
Testrex
Tostrin
Vulvan
Neo-Hombreol
Okasa-Mascul
Andrusol-P
Oreton propionate
Andronate
Testex
Orchisterone
Testosteroni propionas
Androgen
Testosteron propionate
Primotestone
NSC 9166
Homandren (amps)
Testoviron (ampule)
CCRIS 575
Testosterone-17beta propionate
Testosterone-17beta-propionate
Testosterone, propionate
Testosterone-17-beta-propionate
Testosterone (propionate)
Testosteron 17-propionate
Testosterone-17-propionate
NSC-9166
Testosterone propionate ciii
EINECS 200-351-1
UNII-WI93Z9138A
DTXSID9036515
17beta-(Propionyloxy)androst-4-en-3-one
AI3-26378
WI93Z9138A
17beta-Hydroxyandrost-4-en-3-one propionate
NRB-03689
17beta-Hydroxy-4-androsten-3-one 17-propionate
Androst-4-en-3-one, 17beta-hydroxy-, propionate
delta(sup 4)-Androstene-17-beta-propionate-3-one
CHEMBL1170
17beta-Hydroxyandrost-4-en-3-one-17beta-propionate
CHEBI:9466
DTXCID7016515
NSC9166
Testosterone 17.beta.-propionate
Testosterone-17.beta.-propionate
Testosterone propionate [USP:JAN]
[(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] propanoate
NCGC00016254-01
Testosterone 17-propionate
(17beta)-3-oxoandrost-4-en-17-yl propanoate
17-propionyl-17beta-hydroxyandrost-4-en-3-one
Testosterone propionate (USP:JAN)
TESTOSTERONE PROPIONATE (MART.)
TESTOSTERONE PROPIONATE [MART.]
CAS-57-85-2
Androst-4-en-3-one, 17-(1-oxopropoxy)-, (17.beta.)-
testosteron-17-propionat
TESTOSTERONE PROPIONATE (EP MONOGRAPH)
TESTOSTERONE PROPIONATE (USP IMPURITY)
TESTOSTERONE PROPIONATE [EP MONOGRAPH]
TESTOSTERONE PROPIONATE [USP IMPURITY]
TESTOSTERONE PROPIONATE (USP MONOGRAPH)
TESTOSTERONE PROPIONATE [USP MONOGRAPH]
Testosterone Propionate (1.0mg/ml in Acetonitrile)
Orchisterone-P
Testoviron (amps)
Perandren (Amp.)
Prestwick_432
Testex (TN)
17.beta.-(Propionyloxy)androst-4-en-3-one
Androst-4-en-3-one, 17-(1-oxopropoxy)-, (17b)-
Androst-4-en-3-one, 17-(1-oxopropoxy)-, (17beta)-
TEXTES DEPOT
.DELTA.4-androstene-17.beta.-propionate-3-one
17.beta.-hydroxyandrost-4-en-3-one, propionate
3-Oxoandrost-4-en-17-yl propionate, (17.beta.)-
Prestwick0_000401
Prestwick1_000401
Prestwick2_000401
Prestwick3_000401
Androst-4-en-3-one, 17.beta.-hydroxy-, propionate
17-(1-Oxopropoxy)androst-4-en-3-one, (17.beta.)-
SCHEMBL4044
BSPBio_000322
MLS002153796
Testosterone propionate, solid
SPBio_002261
BPBio1_000356
GTPL7100
Testosterone-17.beta.propionate
Androst-4-en-3-one, 17-(1-oxopropoxy)-(17-beta)-
MSK2286
HMS1569A04
HMS2096A04
HMS2272K06
HMS3713A04
Testosterone propionate (Agovirin)
HY-B1269
TESTOSTERONE 17beta-PROPIONATE
TESTOSTERONE PROPIONATE [MI]
Tox21_110330
Tox21_302270
BBL029912
BDBM50215709
LMST02020076
STK801834
Testosterone propionate (JP17/USP)
TESTOSTERONE PROPIONATE [JAN]
AKOS005622513
AKOS015842719
Tox21_110330_1
CCG-220401
CS-4905
DB01420
TESTOSTERONE PROPIONATE [VANDF]
TESTOSTERONE PROPIONATE [WHO-DD]
TESTOSTERONE PROPIONATE [WHO-IP]
NCGC00179602-01
NCGC00179602-03
NCGC00179602-06
NCGC00255481-01
AC-12172
AC-33160
FO157319
SMR000058348
VS-09499
3-Oxoandrost-4-en-17beta-yl propanoate
BCP0726000215
TESTOSTERONE PROPIONATE [GREEN BOOK]
NS00015421
T0028
TESTOSTERONE PROPIONATE [ORANGE BOOK]
TESTOSTERONI PROPIONAS [WHO-IP LATIN]
(17beta)-3-oxoandrost-4-en-17-yl propionate
C08158
D00959
(17beta)-17-(1-Oxopropoxy)androst-4-en-3-one
Testosterone Propionate 1.0 mg/ml in Acetonitrile
Testosterone propionate, tested according to Ph.Eur.
BRD-K90553655-001-03-6
Q10354588
WLN: L E5 B666 OV MUTJ A E FO52 -B&AEF
Androst-4-en-3-one, 17-(1-oxopropoxy)-(17.beta.)-
17-(1-OXOPROPOXY)-(17-BETA)-ANDROST-4-EN-3-ONE
Testosterone propionate, British Pharmacopoeia (BP) Reference Standard
Testosterone propionate, European Pharmacopoeia (EP) Reference Standard
Testosterone propionate, United States Pharmacopeia (USP) Reference Standard
(1S,3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl propanoate
200-351-1
Propionic acid (8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl ester
Propionic acid 10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl ester
Propionic acid 10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl ester(Testosterone Propionate)
Testosterone propionate for system suitability, European Pharmacopoeia (EP) Reference Standard