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Scopolamine hydrobromide

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Identification
Molecular formula
C17H24BrNO4
CAS number
114-49-8
IUPAC name
(8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-acetate;bromide
State
State

Scopolamine hydrobromide is typically found as a solid in its pure form at room temperature. It is stable under normal conditions of storage and handling.

Melting point (Celsius)
199.00
Melting point (Kelvin)
472.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
438.34g/mol
Molar mass
438.3390g/mol
Density
1.3740g/cm3
Appearence

Scopolamine hydrobromide appears as a white or slightly off-white crystalline powder. It is hygroscopic in nature, meaning it can absorb moisture from the environment. Due to its crystal structure, it may have a shimmering appearance under light and is generally free of any lumps or agglomerates.

Comment on solubility

Solubility of (8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-acetate; bromide

The solubility of the compound (8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-acetate; bromide is influenced by several factors:

  • Ionic nature: As a bromide salt, it is expected to exhibit good solubility in polar solvents, particularly in water.
  • Hydroxyl group: The presence of the 2-hydroxy group enhances the compound's ability to form hydrogen bonds with water, further increasing its solubility.
  • Size and structure of the molecule: The bulky bicyclic structure may hinder solubility in nonpolar solvents due to steric hindrance.
  • Temperature: Generally, solubility increases with temperature; therefore, the solubility of this compound may vary significantly at different temperatures.

In conclusion, while the compound has favorable conditions for solubility in aqueous environments due to its ionic and polar characteristics related to the hydroxyl group, the specific solvent interactions and potential steric factors must also be considered for a comprehensive understanding of its solubility behavior.

Interesting facts

Interesting Facts about (8,8-Dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl) 2-Hydroxy-2-phenyl-acetate; Bromide

This compound is an intriguing example of a quaternary ammonium salt, which plays a vital role in various chemical applications. Quaternary ammonium compounds are known for their unique characteristics and versatile uses, making them staples in both industrial and laboratory settings.

Here are some key points that highlight the significance of this compound:

  • Versatile Applications: Compounds like this one are often utilized as ionic liquids, which are gaining popularity for their environmentally friendly characteristics.
  • Surfactant Properties: It can function as a surfactant, decreasing surface tension and enhancing emulsification, making it valuable in the formulation of personal care products and detergents.
  • Medical Relevance: The bicyclic structure is of great interest in medicinal chemistry, potentially leading to therapeutics that target specific biological pathways due to their structural specificity.
  • Research Potential: Researchers are exploring its use in drug delivery systems, where its quaternary ammonium nature can enhance the solubility and permeability of drugs across biological membranes.
  • Chemistry at Play: The presence of multiple functional groups provides diverse reactivity pathways, making it an exciting subject of study for those interested in synthetic organic chemistry.

As with many compounds in this category, the balance between their effectiveness and safety is an essential consideration. Though they are widely useful, understanding their environmental impact and potential toxicity remains a critical area of research.

In summary, the compound (8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-acetate; bromide stands as a noteworthy example of how complex organic compounds can lead to innovative solutions in various fields. Its unique structure and properties make it an exciting topic for further exploration in chemistry!

Synonyms
Methylhomatropine bromide
80-49-9
Omatropina metilbromuro
8-Methylhomatropinium bromide
Tropinium methobromide mandelate
Homatropine methyl bromide
Homatropine methobromide
Methylhomatropinum bromatum
3-alpha-Hydroxy-8-methyl-1-alpha-H,5-alpha-H-tropanium bromide mandelate
NSC34399
SCHEMBL77827
CHEBI:50373
AKOS015896228
DB00725
3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-8-azabicyclo[3.2.1]octan-8-ium bromide
3-[2-hydroxy(phenyl)acetoxy]-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide
NCGC00094694-01
NCGC00094694-02
DB-056442
D90875
EN300-22283576