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Taxol

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Identification
Molecular formula
C47H51NO14
CAS number
33069-62-4
IUPAC name
(8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl) carbamate
State
State

At room temperature, Taxol is typically in a solid state, appearing as a white crystalline powder.

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.15
Boiling point (Celsius)
774.00
Boiling point (Kelvin)
1 047.15
General information
Molecular weight
853.91g/mol
Molar mass
853.9060g/mol
Density
1.6600g/cm3
Appearence

Taxol appears as a white crystalline powder. It is sparingly soluble in water, but soluble in organic solvents such as methanol, ethanol, and DMSO.

Comment on solubility

Solubility of (8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl) carbamate

The solubility of the compound with the formula C47H51NO14 can be influenced by several factors including its molecular structure, polarity, and the presence of functional groups.

Factors Influencing Solubility

  • Molecular Weight: With a high molecular weight of 839.87 g/mol, solubility in water may be limited.
  • Polarity: The presence of multiple methoxy groups in the compound generally enhances polarity, potentially increasing solubility in polar solvents such as methanol and ethanol.
  • Hydrogen Bonding: The presence of the carbamate function can promote hydrogen bonding, which also influences solubility in polar media.
  • Solvent Type: The compound may exhibit variable solubility in organic solvents compared to aqueous solutions, hence it's always crucial to assess solubility in specific solvents.

General Insights

Due to the complex nature of its structure, one might say, "Solubility is dictated by interplay;" while it may show some solubility in polar organic solvents, it is likely poorly soluble in non-polar solvents.
Therefore, experimental determination of its solubility is essential to fully understand its behavior in various environments.

Interesting facts

Interesting Facts about (8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl) carbamate

This compound is an intriguing member of the class of organic molecules known as carbamates. It features a highly complex structure, which is a testament to the amazing diversity found in chemical compounds. Here are some interesting points about it:

  • Structural Complexity: The name indicates a multi-ring system with multiple substituents, showcasing the possibilities of organic synthesis and structure manipulation that challenge chemists to explore new domains.
  • Biological Relevance: Compounds containing azabicyclo structures often exhibit unique biological activities, which could lead to potential applications in pharmaceuticals, especially those aimed at complex diseases.
  • Synthesis Challenges: The synthesis of this compound likely requires advanced techniques due to its intricate functional groups and stereochemistry, making it a suitable subject for students delving into organic chemistry.
  • Applications: Investigating the properties and applications of this compound may yield insights into drug design, agrochemicals, or materials science, where such complexes can serve as key intermediates.
  • Research Potential: As scientists continue to probe the structure-activity relationships of such compounds, the potential for discovering new therapeutic agents remains vast.

In summary, the fascinating features of this molecule, alongside its structural intricacies, provide a rich ground for exploration. As noted by chemists, "The beauty of chemistry lies in its complexity and simplicity, intertwined in the structures we study." With ongoing advances in synthetic methods, compounds like this one hold the promise of novel insights in both academic research and practical applications.

Synonyms
herbimycin a
70563-58-5
(8,13,14,17-Tetramethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl) carbamate