Skip to main content

Flunarizine

ADVERTISEMENT
Identification
Molecular formula
C26H26F2N2O
CAS number
52468-60-7
IUPAC name
8-phenyl-2-piperazin-1-yl-chromen-4-one
State
State

At room temperature, Flunarizine is in a solid state. It is a crystalline powder, indicating its stability in this form under normal atmospheric conditions.

Melting point (Celsius)
143.00
Melting point (Kelvin)
416.15
Boiling point (Celsius)
738.30
Boiling point (Kelvin)
1 011.45
General information
Molecular weight
404.50g/mol
Molar mass
404.4810g/mol
Density
1.2000g/cm3
Appearence

Flunarizine is typically found in the form of a white to off-white crystalline powder.

Comment on solubility

Solubility Overview of 8-phenyl-2-piperazin-1-yl-chromen-4-one

The solubility of 8-phenyl-2-piperazin-1-yl-chromen-4-one (C26H26F2N2O) presents some intriguing aspects that can be highlighted:

  • Polarity Considerations: This compound features both polar and non-polar elements, given its aromatic and piperazinyl structures. Its solubility in various solvents greatly depends on their polarity.
  • Solvent Compatibility:
    • Likely soluble in organic solvents such as ethanol, methanol, or dichloromethane due to the presence of non-polar phenyl and chromenyl rings.
    • Limited solubility in polar solvents like water, as extensive hydrogen bonding and dipole interactions may not sufficiently stabilize the compound.
  • Temperature Influence: Like many organic compounds, its solubility may increase with temperature, due to enhanced molecular motion overcoming intermolecular forces.

In conclusion, the solubility of C26H26F2N2O can be summarized as being significantly influenced by the solvent polarity, temperature, and the structural characteristics of the compound itself.

Interesting facts

Exploring 8-phenyl-2-piperazin-1-yl-chromen-4-one

The compound 8-phenyl-2-piperazin-1-yl-chromen-4-one is a fascinating derivative of the chromone family, known for its diverse biological activities and structural versatility. As a chemist, one cannot help but appreciate the intricate design of this molecule, which combines a chromone structure with piperazine and phenyl groups.

Key features that make this compound notable:

  • Pharmacological Potential: Compounds in the chromone class have shown promises in medicinal chemistry, particularly as anti-inflammatory and anti-cancer agents. The presence of the piperazine moiety may further enhance its interaction with biological targets, potentially leading to novel therapeutic applications.
  • Diverse Applications: Beyond medicinal uses, chromone derivatives are employed in various fields including agrochemicals, dyes, and organic materials. This versatility opens avenues for interdisciplinary research.
  • Synthetic Interest: The synthesis of this compound provides chemists with challenges and opportunities to develop new strategies for constructing multifunctional compounds that could lead to effective drugs.

This compound's unique structure not only makes it an interesting subject for laboratory synthesis but also paves the way for further exploration in pharmacology. In the words of a renowned chemist, “The greatest discoveries arise from the interplay of structure and function.” Likewise, understanding how the arrangement of atoms in 8-phenyl-2-piperazin-1-yl-chromen-4-one affects its behavior can lead to groundbreaking findings in drug development.

As students or scientists delve deeper into the realm of such compounds, they are likely to uncover new insights that bridge the gap between synthetic chemistry and biological research, demonstrating the importance of multidisciplinary approaches in modern science.

Synonyms
154447-38-8
LY 303511
LY303511
ly-303511
2-Piperazinyl-8-phenyl-4H-1-benzopyran-4-one
8-phenyl-2-piperazin-1-ylchromen-4-one
8-phenyl-2-(piperazin-1-yl)-4h-chromen-4-one
4H-1-Benzopyran-4-one,8-phenyl-2-(1-piperazinyl)-
2-(4-Piperazinyl)-8-phenyl-4H-1-benzopyran-4-one
8-Phenyl-2-Piperazin-1-Yl-Chromen-4-One
CHEMBL1363184
DTXSID90165632
8-Phenyl-2-(1-piperazinyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 8-phenyl-2-(1-piperazinyl)-
SCHEMBL619297
GTPL6005
DTXCID0088123
CHEBI:92399
HMS3229G19
HMS3269C09
HMS3413M04
HMS3677M04
BCP08239
EX-A1746
BDBM50210161
NSC736787
AKOS024457087
CCG-206767
CS-1384
FL29540
NSC-736787
SDCCGSBI-0086687.P003
NCGC00161407-01
NCGC00161407-02
NCGC00161407-03
NCGC00161407-08
AC-32894
BP-25363
DA-33425
HY-15643
LY-303511(Nv-128)?
8-PHENYL-2-(PIPERAZIN-1-YL)CHROMEN-4-ONE
BRD-K22385716-001-01-7
BRD-K22385716-001-02-5
Q27082883
LY 303511 - CAS 154447-38-8
8DQ