Ticarcillin | Solubility of Things

Identification

Molecular formula

C₁₅H₁₆N₃O₆S₂

CAS number

34787-01-4

IUPAC name

8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

State

At room temperature, ticarcillin appears as a solid. However, in medicinal and pharmaceutical applications, it is frequently used and administered as a soluble form in injectable solutions, often as its sodium salt.

Melting point (Celsius)

195.00

Melting point (Kelvin)

468.00

Boiling point (Celsius)

280.00

Boiling point (Kelvin)

553.00

General information

Molecular weight

384.43g/mol

Molar mass

384.4200g/mol

Density

1.8000g/cm³

Appearence

Ticarcillin generally presents as a white to off-white crystalline powder. It is typically available in a more stable, reconstituted form as its sodium salt for injectable solutions. This form is often slightly hygroscopic, absorbing moisture from the air.

Comment on solubility

Solubility of 8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This compound, with the formula C₁₅H₁₆N₃O₆S₂, presents a unique profile in terms of solubility due to its complex structure and the various functional groups contained within. Understanding the solubility characteristics of this compound can be pivotal for its potential applications in various fields.

Factors Influencing Solubility

Polarity: The presence of polar functional groups such as carboxylic acids and ammonium can enhance solubility in polar solvents like water.
Hydrogen Bonding: The ability to form hydrogen bonds through -COOH and -NH groups may contribute positively to solubility.
Hydrophobic Regions: The thienyl and bicyclo structures can introduce hydrophobic characteristics, potentially reducing solubility in aqueous environments.
pH Sensitivity: The solubility may also vary significantly with pH, especially due to the ionizable carboxylic acid group.

Expected Solubility Behavior

Based on these factors, it can be inferred that:

The compound is likely to be more soluble in polar solvents than in nonpolar ones.
In acidic conditions, it may achieve increased solubility due to protonation of the pyridine nitrogen.
At neutral pH, solubility might be moderate, reflecting a balance between hydrophilic and hydrophobic interactions.

In conclusion, while definitive solubility data for this specific compound may not be readily available, considering its structural features and functional groups provides valuable insight into its likely solubility characteristics. Further experimental investigations would be essential to determine precise solubility values.

Interesting facts

Fascinating Insights into 8-Oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

This compound, with its intricate structure and unique characteristics, is a remarkable example of the complexity found in organic chemistry. As a derivative of bicyclic systems, it features a mix of amine and thia functionalities which contribute to its biological activities. Here are some intriguing aspects:

Biological Relevance: Compounds of this nature often exhibit significant pharmacological properties, making them intriguing targets for drug design and development.
Pyridine Integration: The pyridine moiety present in the structure suggests potential interactions with various biological targets, particularly in enzyme inhibition.
Thienyl Substitution: The presence of thienyl groups may offer unique photochemical properties, which could be harnessed in organic photonic materials.
Complexity of Synthesis: The synthesis of such compounds is often challenging due to their multifaceted structures, demanding inventive strategies and methodologies.

A quote from a prominent chemist aptly summarizes the allure of such compounds: "In the complexity of structure lies the promise of discovery." As researchers delve deeper into the synthesis and applications of this compound, they unlock potential therapeutic avenues and material innovations.

Furthermore, studying its interactions and mechanisms opens up a wider understanding of how structured compounds can influence biological systems and catalyze significant reactions in organic chemistry.

Synonyms

Floridin

Intrasporin

Ampligram

Ceporan

Ceporine

Cilifor

Deflorin

Faredina

Keflodin

Keflordin

Kefspor

Lloncefal

Sefacin

Betaine cephaloridine

NINDS_000477

CEPH 87/4

LILLY 40602

SCH 11527

Spectrum_001447

Spectrum2_000923

Spectrum3_001150

Spectrum4_000327

Spectrum5_001178

BSPBio_002679

KBioGR_000673

KBioSS_001927

DivK1c_000477

SPBio_000826

KBio1_000477

KBio2_001927

KBio2_004495

KBio2_007063

KBio3_002179

13057-93-7

IDI1_000477

8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

PD194048

7-(.alpha.-(2-Thienyl)acetamido)-3-(1-pyridylmethyl)-3-cephem-4-carboxylic acid betaine

7-(Thiophene-2-acetamido)-3-(1-pyridylmethyl)-3-cephem-4-carboxylic acid betaine

(6R-trans)-1-[[2-Carboxy-8-oxo-7[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]-methyl]pyridinium inner salt

1-[(7'-.beta.-[2-(2-Thienyl)acetamido]-8'-oxo-1'-aza-5'-thiabicyclo[4.2.0]oct-2'-en-3'-yl)methyl]pyridinium-2'-carboxylate

Pyridinium, 1-((2-carboxy-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-, hydroxide, inner salt

Pyridinium, 1-[[2-carboxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, hydroxide, inner salt, (6R-trans)-

SR-05000002040

SR-05000002040-1

1-[[(6R)-2-Carboxy-8-oxo-7alpha-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium