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Tropicamide

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Identification
Molecular formula
C17H24NO3
CAS number
1508-75-4
IUPAC name
(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-acetate
State
State
At room temperature, tropicamide is typically found as a solid. Specifically, it is a crystalline powder commonly used in pharmaceutical formulations.
Melting point (Celsius)
95.00
Melting point (Kelvin)
368.20
Boiling point (Celsius)
325.60
Boiling point (Kelvin)
598.80
General information
Molecular weight
284.37g/mol
Molar mass
284.3660g/mol
Density
1.2000g/cm3
Appearence
Tropicamide generally appears as a white to off-white crystalline powder. The powder is odorless and it is often used in its crystalline form in various pharmaceutical preparations.
Comment on solubility

Solubility of (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-acetate

The solubility of the compound (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-acetate (C17H24NO3) exhibits some intriguing characteristics that are worth noting:

  • Polar vs Nonpolar Nature: Due to the presence of the hydroxyl group (-OH) and the aromatic phenyl ring, this compound displays a degree of polarity, which may enhance its solubility in polar solvents such as water and ethanol.
  • Hydrophobic Interactions: The bicyclic structure contributes to hydrophobic interactions, indicating that while it may dissolve in polar solvents, it could also exhibit solubility in organic solvents like chloroform and dichloromethane.
  • Temperature Influence: The solubility may vary significantly with temperature. Generally, solubility tends to increase with temperature for organic compounds, which could be observed with this particular molecule.
  • Common Solvents: It is likely soluble in a variety of solvents, including:
    • Ethanol
    • Acetone
    • Dimethyl sulfoxide (DMSO)

In conclusion, the solubility of (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-acetate is influenced by its molecular structure, polarity, and environmental conditions. As with many compounds, it would be prudent to conduct experimental solubility tests in order to obtain precise data for practical applications.

Interesting facts

Interesting Facts About (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-acetate

The compound known as (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-acetate is a fascinating member of the family of organic compounds. Here are some interesting aspects worth noting:

  • Structural Complexity: This compound features a bicyclic structure, which is quite common in various natural products and pharmaceutical agents. The unique bicyclo[3.2.1] framework creates interesting steric arrangements that can have significant implications on its reactivity and biological interactions.
  • Pharmacological Potential: Compounds with similar structures often exhibit biological activity. Potential areas of research could include their effects as neurotransmitter transporter inhibitors or muscle relaxants, given the presence of the azabicyclo structure.
  • Synthesis Applications: The chemical synthesis of such compounds can involve *multiple methods*, including traditional organic reactions, which provide valuable insight into the principles of organic chemistry and synthetic methodology.
  • Analytical Chemistry: Characterizing this compound may involve use of various techniques such as NMR spectroscopy, mass spectrometry, and X-ray crystallography, each revealing different aspects of its structure and properties.
  • Interdisciplinary Relevance: The study of this compound transcends mere chemistry, affecting fields such as medicinal chemistry, pharmacology, and toxicology, illustrating the interconnectedness of chemical sciences.

In summary, the compound (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-acetate encapsulates a world of possibilities for exploration—striking a balance between structural beauty and potential utility in medicine and pharmacology. As one saying goes, *“The realm of chemistry is vast, and every compound has a story waiting to be uncovered.”*

Synonyms
HOMATROPINE
Homotropine
NSC60600
Homatropin
Homoatropine
Mandelytropeine
Mandelyltropeine
87-00-3
8-Methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate
(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenylacetate
Mandelic acid, 3d-tropanyl ester
114173-36-3
Benzeneacetic acid, .alpha.-hydroxy-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-(.+/-.)-
NSC-60600
Tropine, mandelate
(.+/-.)-Homatropine
Lopac0_000592
SCHEMBL23970
CHEMBL1237117
BDBM82370
DTXSID60858968
ZTVIKZXZYLEVOL-UHFFFAOYSA-N
NSC_5821
STK693930
AKOS005605558
CCG-204681
SDCCGSBI-0050574.P003
CAS_87-00-3
NCGC00015489-02
NCGC00015489-03
NCGC00015489-06
NCGC00162198-01
NCI60_004650
DB-056963
NS00127348
AP-163/40806836
L000927
SR-01000075900-6
1.alpha.H,5.alpha.H-Tropan-3-.alpha.-ol, mandelate
8-Methyl-8-azabicyclo[3.2.1]octan-3-yl hydroxy(phenyl)acetate
3.alpha.-Hydroxy-1.alpha.H,5.alpha.H-tropanium mandelate (ester)
8-Methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate #
8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2-phenylacetate
[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2-phenylacetate