Skip to main content

Taxol

ADVERTISEMENT
Identification
Molecular formula
C47H51NO14
CAS number
33069-62-4
IUPAC name
8-hydroxy-7-isopropyl-1-methyl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one
State
State

Taxol is a solid at room temperature, typically encountered as a crystalline powder due to its complex molecular structure involving aromatic and alicyclic rings.

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.15
Boiling point (Celsius)
270.00
Boiling point (Kelvin)
543.15
General information
Molecular weight
853.91g/mol
Molar mass
853.9060g/mol
Density
1.6600g/cm3
Appearence

Taxol is generally a white crystalline powder. It is known for its distinctive structure, which includes numerous chiral centers and multiple rings, contributing to its appearance and crystalline nature.

Comment on solubility

Solubility of 8-hydroxy-7-isopropyl-1-methyl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one

The compound 8-hydroxy-7-isopropyl-1-methyl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one, with the chemical formula C47H51NO14, showcases intricate solubility properties that arise from its unique structural complexity. Understanding its solubility can be approached by considering several key factors:

  • Polar vs. Nonpolar: Due to the presence of multiple hydroxyl (-OH) and ether functional groups (-O-), this compound may exhibit significant polar characteristics, likely making it soluble in polar solvents like water, while lesser solubility in nonpolar solvents may be observed.
  • Molecular Weight: With a high molecular weight, the solubility in solvents often correlates inversely. Lower solubility in common organic solvents is anticipated.
  • Hydrogen Bonding: The potential for intramolecular and intermolecular hydrogen bonding due to hydroxyl groups may influence the solubility favorably in polar environments.

It is essential to note that the specific solubility characteristics can vary based on factors such as temperature and pH. As with many specialized compounds, experimental validation is crucial; thus, one might find varying solubility states (e.g., "soluble," "sparingly soluble," or "insoluble") in different contexts. In summary, while theoretical predictions can guide expectations, empirical testing remains the best method to ascertain actual solubility behavior.

Interesting facts

Interesting Facts About 8-hydroxy-7-isopropyl-1-methyl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one

8-hydroxy-7-isopropyl-1-methyl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one is a fascinating compound with a complex structure that showcases the beauty of organic chemistry. Here are some interesting facts:

  • Unique Structure: This compound is a part of the heptacyclical category, meaning it consists of seven fused rings. Its intricate architecture is the result of both natural and synthetic processes in organic synthetics.
  • Oxidation Importance: The presence of four ether linkages in the molecule indicates its oxidized nature, which can influence its reactivity and stability in a variety of chemical environments.
  • Biological Activity: Compounds similar to this one are often investigated for their potential biological effects, including anti-inflammatory and antimicrobial properties. Their unique functional groups make them candidates for pharmaceutical development.
  • Applications: The detailed structure allows for innovative applications in different fields such as material science, drug formulation, and as ligands in coordination chemistry.
  • Research Interest: The complexity of this compound has garnered attention among researchers focusing on polycyclic compounds and their applications in advanced materials and drug discovery.

As a chemistry student or scientist, the study of such compounds not only enhances understanding of synthetic methods but also broadens perspectives on the potential utility of complex molecules in modern science.

Synonyms
SCHEMBL26443574
DTXSID90860559
Triptolidefrom Tripterygium wilfordii
LS-14791
(1S,2S,4S,5S,7R,8R,9S,11S,13S)-8-hydroxy-1-methyl-7-propan-2-yl-3,6,10,16-tetraoxaheptacyclo[11.7.0.0^{2,4.0^{2,9.0^{5,7.0^{9,11.0^{14,18]icos-14(18)-en-17-one
6-Hydroxy-8b-methyl-6a-(propan-2-yl)-3b,4,4a,6,6a,7a,7b,8b,9,10-decahydrotrisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1(3H)-one