Xanthohumol | Solubility of Things

Identification

Molecular formula

C₂₁H₂₂O₅

CAS number

6754-58-1

IUPAC name

8-hydroxy-5,7-dimethoxy-3-methyl-2-(3,4,5,6,11-pentamethyltrideca-7,9,11-trienyl)chromen-4-one

State

At room temperature, xanthohumol is a solid. It is typically handled in powdered form for use in research and industrial applications.

Melting point (Celsius)

157.50

Melting point (Kelvin)

430.70

Boiling point (Celsius)

808.65

Boiling point (Kelvin)

1 081.80

General information

Molecular weight

354.47g/mol

Molar mass

354.4690g/mol

Density

1.1500g/cm³

Appearence

Xanthohumol is a pale yellow crystalline solid. It typically appears as fine powdery crystals and can be somewhat sticky due to its slightly hydrophobic nature.

Comment on solubility

Solubility of 8-hydroxy-5,7-dimethoxy-3-methyl-2-(3,4,5,6,11-pentamethyltrideca-7,9,11-trienyl)chromen-4-one

The solubility of the compound C₂₁H₂₂O₅, also known as 8-hydroxy-5,7-dimethoxy-3-methyl-2-(3,4,5,6,11-pentamethyltrideca-7,9,11-trienyl)chromen-4-one, can be quite intricate due to its complex structure. Solubility is influenced by several factors, particularly the polarity of the molecule and the presence of functional groups.

Polarity: As a chromenone derivative, the presence of multiple methoxy (-OCH₃) groups suggests that the compound may exhibit moderate polarity.
Functional Groups: The hydroxyl (-OH) group typically enhances solubility in polar solvents like water. Nevertheless, other segments of the molecule could influence overall solubility.
Solvent Interaction: This compound is likely to be more soluble in organic solvents such as ethanol or methanol, compared to water due to its lipophilic regions.

In conclusion, while the presence of polar functional groups might suggest some degree of solubility in polar solvents, the extensive hydrocarbon chain and sublime structural complexity could potentially limit its overall solubility in aqueous environments. It is thus crucial to experiment with various solvent systems to properly assess the solubility characteristics of C₂₁H₂₂O₅. Remember, as with many organic compounds, “the rule of thumb is like dissolves like” when it comes to solubility!

Interesting facts

Exploring 8-Hydroxy-5,7-Dimethoxy-3-Methyl-2-(3,4,5,6,11-Pentamethyltrideca-7,9,11-Trienyl)Chromen-4-One

This fascinating compound is a member of the flavonoid family, which is known for its diverse biological activities. Its unique structure contributes to a variety of potential applications in fields such as pharmacology and natural product chemistry. Here are some intriguing facts about this compound:

Biological Activity: Flavonoids, including this compound, are often studied for their antioxidant properties, which can protect cells from oxidative stress. This activity makes them interesting for research in aging and chronic diseases.
Natural Sources: Many flavonoids are derived from plants, and they frequently exhibit health benefits. This encourages further exploration into plant-based sources of this compound for potential therapeutic uses.
Structural Complexity: The intricate chemical structure of this compound, particularly the presence of multiple methoxy groups and the long side chain, provides insights into how slight modifications can influence biological activities. As a result, chemists are motivated to synthesize similar molecules to explore new biological interactions.
Potential Drug Development: The research community is enthusiastic about the potential for flavonoids in drug formulation, especially in anticancer therapies and the treatment of cardiovascular diseases.

In conclusion, the study of 8-hydroxy-5,7-dimethoxy-3-methyl-2-(3,4,5,6,11-pentamethyltrideca-7,9,11-trienyl)chromen-4-one offers a plethora of opportunities for both scientific exploration and industrial application. As one researcher noted, “The more we understand the complexity of these compounds, the more we can harness their potential for innovations in health and medicine.”