Skip to main content

8-Ethyl-5-oxo-2-pyrrolidin-1-yl-pyrido[2,3-d]pyrimidine-6-carboxylic acid

ADVERTISEMENT
Identification
Molecular formula
C15H15N3O3
CAS number
471929-95-6
IUPAC name
8-ethyl-5-oxo-2-pyrrolidin-1-yl-pyrido[2,3-d]pyrimidine-6-carboxylic acid
State
State

At room temperature, 8-ethyl-5-oxo-2-pyrrolidin-1-yl-pyrido[2,3-d]pyrimidine-6-carboxylic acid is typically found in a solid state. It is known for its stability under standard laboratory conditions.

Melting point (Celsius)
275.00
Melting point (Kelvin)
548.15
Boiling point (Celsius)
550.00
Boiling point (Kelvin)
823.15
General information
Molecular weight
321.33g/mol
Molar mass
321.3260g/mol
Density
1.5500g/cm3
Appearence

The appearance of this compound is generally described as a crystalline solid, typically ranging from off-white to light beige in color. The specific hue can vary depending on the degree of purity and the presence of any impurities.

Comment on solubility

Solubility of 8-ethyl-5-oxo-2-pyrrolidin-1-yl-pyrido[2,3-d]pyrimidine-6-carboxylic acid (C15H15N3O3)

The solubility of 8-ethyl-5-oxo-2-pyrrolidin-1-yl-pyrido[2,3-d]pyrimidine-6-carboxylic acid is an important property that can significantly influence its behavior in various environments. Understanding this solubility can be summarized through several key points:

  • Polarity: The presence of polar functional groups, such as carboxylic acid, suggests that this compound may exhibit improved solubility in polar solvents like water.
  • Hydrogen Bonding: The capacity of the carboxylic acid functional group to participate in hydrogen bonding can enhance its solubility in biological systems and aqueous solutions.
  • Influence of Substituents: The ethyl and pyrrolidinyl groups could influence the overall hydrophobic character, potentially moderating solubility.
  • pH Dependency: The solubility of carboxylic acids generally increases with increasing pH due to deprotonation, which could alter its solubility under different conditions.
  • Solvent Effects: Compatibility with different organic solvents may vary, and the choice of solvent can significantly affect solubility profiles.

In conclusion, while specific experimental data is essential for precise solubility predictions, factors mentioned above play a crucial role in determining the solubility behavior of 8-ethyl-5-oxo-2-pyrrolidin-1-yl-pyrido[2,3-d]pyrimidine-6-carboxylic acid. Understanding these aspects is vital for applications in pharmaceuticals and material sciences. As the saying goes, "Like dissolves like," making it imperative to consider the interactions at play for optimal formulation and usage.

Interesting facts

8-Ethyl-5-oxo-2-pyrrolidin-1-yl-pyrido[2,3-d]pyrimidine-6-carboxylic Acid

This compound belongs to a class of organic compounds known for their diverse biological activities, especially in the field of medicinal chemistry. Let's explore some fascinating aspects of this compound:

  • Structural Complexity: The structure of this compound features a unique combination of pyrrolidine and pyrimidine rings, reflecting rich chemical properties that can be exploited for various applications.
  • Potential Therapeutic Applications: Many compounds with similar structural motifs are found to exhibit promising activity as anti-cancer agents, anti-inflammatory medications, and as inhibitors for various enzymes. This compound could potentially lead to breakthroughs in drug design.
  • Role in Synthesis: The presence of functional groups such as the carboxylic acid may aid in engaging in further chemical reactions and facilitating syntheses of more complex molecules. This opens up avenues for developing hybrid compounds with enhanced efficacy.
  • Biological Implications: Compounds like this are often studied for their interaction with biological receptors, which could reveal insights into their potential as pharmacological agents. Understanding how they bind and modify the activity of target proteins is crucial.
  • Research Significance: Ongoing studies of similar heterocyclic compounds have shed light on their structure-activity relationships (SAR), aiding scientists in modifying structures to optimize effects. This compound is part of a broader scientific endeavor aimed at discovering novel therapeutic agents.

In conclusion, 8-ethyl-5-oxo-2-pyrrolidin-1-yl-pyrido[2,3-d]pyrimidine-6-carboxylic acid exemplifies the intricate world of organic chemistry, where small changes in molecular structure can lead to significant variations in biological activity. As researchers continue to peel back the layers of its potential, we can anticipate exciting developments in the field of drug discovery.

Synonyms
piromidic acid
19562-30-2
Bactramyl
Panacid
Enterol
Urisept
Zaomeal
Reelon
Acido piromidico
Acide piromidique
Actrun C
Gastrurol
Septural
Pirodal
Uropir
Acidum piromidicum
Piromidate
PD-93
PD 93
Piromidic acid [INN:JAN]
8-ethyl-5-oxo-2-(pyrrolidin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid
Acide piromidique [INN-French]
Acido piromidico [INN-Spanish]
Acidum piromidicum [INN-Latin]
EINECS 243-161-4
3I12WH4EWF
Panacid (TN)
NSC 291120
NSC-291120
BRN 0625004
DTXSID4045424
PIROMIDIC ACID [MI]
PIROMIDIC ACID [INN]
PIROMIDIC ACID [JAN]
8-Ethyl-5,8-dihydro-5-oxo-2-(1-pyrrolidinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid
Pyrido(2,3-d)pyrimidine-6-carboxylic acid, 8-ethyl-5,8-dihydro-5-oxo-2-(1-pyrrolidinyl)-
PIROMIDIC ACID [MART.]
DTXCID2025424
PIROMIDIC ACID [WHO-DD]
CHEBI:32019
NSC291120
8-Ethyl-5-oxo-2-(1-pyrrolidinyl)-5,8-dihydropyrido(2,3-d)pyrimidine-6-carboxylic acid
NCGC00016743-01
CAS-19562-30-2
Pyrido(2,3-d)pyrimidine-6-carboxylic acid, 5,8-dihydro-8-ethyl-5-oxo-2-(1-pyrrolidinyl)-
PIROMIDIC ACID (MART.)
Acide piromidique (INN-French)
Acido piromidico (INN-Spanish)
Acidum piromidicum (INN-Latin)
Acid, Piromidic
8-ethyl-5-oxo-2-pyrrolidin-1-ylpyrido[6,5-d]pyrimidine-6-carboxylic acid
Pyrido[2,3-d]pyrimidine-6-carboxylic acid, 8-ethyl-5,8-dihydro-5-oxo-2-(1-pyrrolidinyl)-
SR-01000872672
UNII-3I12WH4EWF
piromidic-acid
8-ethyl-5-oxo-2-pyrrolidin-1-ylpyrido(6,5-d)pyrimidine-6-carboxylic acid
8-Ethyl-5,8-dihydro-5-oxo-2-(-1-pyrrolidinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid
8-Ethyl-5,8-dihydro-5-oxo-2-(-1-pyrrolidinyl)pyrido[2,3-d]pyrimidine-6-carboxylic acid
8-ethyl-5-oxo-2-(pyrrolidin-1-yl)-5,8-dihydropyrido(2,3-d)pyrimidine-6-carboxylic acid
8-ethyl-5-oxo-2-(pyrrolidin-1-yl)-5H,8H-pyrido(2,3-d)pyrimidine-6-carboxylic acid
8-ethyl-5-oxo-2-(pyrrolidin-1-yl)-5H,8H-pyrido[2,3-d]pyrimidine-6-carboxylic acid
Prestwick_968
Spectrum_001441
Prestwick0_000805
Prestwick1_000805
Prestwick2_000805
Prestwick3_000805
Spectrum2_001465
Spectrum3_000776
Spectrum4_000792
Spectrum5_001025
Piromidic acid (Standard)
8-ethyl-5-oxo-2-pyrrolidin-1-ylpyrido[2,3-d]pyrimidine-6-carboxylic acid
Piromidic acid (JAN/INN)
Oprea1_855246
BSPBio_000669
BSPBio_002452
KBioGR_001264
KBioSS_001921
DivK1c_000510
SCHEMBL134848
SPECTRUM1502045
SPBio_001389
SPBio_002590
BPBio1_000737
CHEMBL311350
GTPL12475
HMS501J12
HY-B1043R
KBio1_000510
KBio2_001921
KBio2_004489
KBio2_007057
KBio3_001672
J01MB03
NINDS_000510
HMS1570B11
HMS1921H14
HMS2097B11
HMS3714B11
Pharmakon1600-01502045
HY-B1043
Tox21_110587
CCG-39222
NSC758179
AKOS030239809
Tox21_110587_1
CS-4564
DB13744
FP27084
NSC-758179
IDI1_000510
NCGC00016743-02
NCGC00016743-03
NCGC00016743-04
NCGC00016743-05
NCGC00016743-08
NCGC00094954-01
NCGC00094954-02
NCGC00178647-01
NCGC00178647-02
BS-49295
DA-56901
SBI-0051714.P002
NS00009244
SW197054-3
D01431
E78426
AB00052264_04
AB00052264_05
Q745206
SR-01000872672-1
SR-01000872672-2
BRD-K37682401-001-05-1
BRD-K37682401-001-06-9
BRD-K37682401-001-08-5
BRD-K37682401-001-09-3
BRD-K37682401-213-01-1
Pyrido[2, 8-ethyl-5,8-dihydro-5-oxo-2-(1-pyrrolidinyl)-
8-ethyl-5-oxo-2-pyrrolidin-1-yl-pyrido[2,3-d]pyrimidine-6-carboxylic acid
2-Pyrrolidino-5-oxo-8-ethyl-5,8-dihydro-pyrido[2,3 -d]pyrimidine-6-carboxylic acid
8-Ethyl-5,8-dihydro-5-oxo-2-(-1-pyrrolidinyl)pyrido[2,3-d]pyrimidine-6- carboxylic acid
243-161-4
8-Ethyl-5,8-dihydro-5-oxo-2-(1-pyrrolidinyl)pyrido[2,3-d]pyrimidine-6-carboxylic acid;5,8-Dihydro-8-ethyl-5-oxo-2-pyrrolidinopyrido[ 2,3-d]pyrimidine-6-carboxylic acid;Bactramyl
Pyrido(2,3-d)pyrimidine-6-carboxylic acid, 8-ethyl-5,8-dihydro-5-oxo-2-(1-pyrrolidinyl)-(8CI)
Pyrido(2,3-d)pyrimidine-6-carboxylic acid, 8-ethyl-5,8-dihydro-5-oxo-2-(1-pyrrolidinyl)-(8CI)(9CI)