Interesting facts
Interesting Facts about 8-Chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine
8-Chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine is a fascinating compound due to its structural complexity and potential applications. Here are some intriguing facts about this compound:
- Pharmacological Interest: This compound belongs to a class of chemicals known for their neuroactive properties. Its unique structure may enable it to interact with various neurotransmitter systems, which could make it a candidate for therapeutic use in treating mental health disorders.
- Mechanism of Action: Understanding how compounds like this one work at the molecular level can provide insights into their therapeutic effects. Researchers explore their ability to modulate receptor activity, potentially impacting anxiety and mood regulation.
- Structure-Activity Relationship (SAR): The presence of the 4-methylpiperazine moiety suggests a significant role in the compound's biological activity. Variations in the structure can lead to different pharmacological profiles, offering a rich area for exploration in medicinal chemistry.
- Chlorine's Role: The introduction of chlorine in organic compounds often enhances bioactivity. In this case, the 8-chloro aspect is believed to increase lipophilicity, aiding in the compound's ability to cross the blood-brain barrier.
- Potential Research Applications: This compound may serve as a lead molecule in drug development, inspiring modifications and derivatives aimed at improving efficacy and reducing side effects.
- Multifactorial Effects: While the research on this specific structure is still emerging, similar compounds have shown potential in various therapeutic areas, such as anti-psychotic, anxiolytic, and cognitive-enhancing effects.
As scientists continue to delve into the properties and applications of compounds like 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine, the rich interplay between chemistry and biology offers endless opportunities for discovery and innovation. Understanding the nuances of such complex molecules is crucial for advancing medicine and improving mental health outcomes.
Synonyms
loxapine
1977-10-2
Cloxazepine
Oxilapine
Loxitane
Loxapin
Dibenzacepin
Dibenzoazepine
Adasuve
Loxapina
Loxapinum
Hydrofluoride 3170
SUM 3170
CL-62362
Lossapina
Loxapinum [INN-Latin]
Loxapina [INN-Spanish]
SUM-3170
HF3170
Dibenz[b,f][1,4]oxazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-
HF 3170
LW 3170
Staccato loxapine
S-805
2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine
CL 62362
CHEBI:50841
CL 62,362
HSDB 3111
LER583670J
S 805
EINECS 217-835-3
CHEMBL831
2-Chloro-11-(4-methyl-1-piperazinyl)dibenz(b,f)(1,4)oxazepine
BRN 0626753
Dibenz(b,f)(1,4)oxazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-
UNII-LER583670J
DTXSID7023229
2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine
2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine
8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine
AZ-004
Lossapina [DCIT]
2-Chloro-11-(4-methyl-1-piperazinyl)-dibenz(b,f)(1,4)oxazepine
Loxapinum (INN-Latin)
Loxapina (INN-Spanish)
LOXAPINE (MART.)
LOXAPINE [MART.]
C18H18ClN3O
Loxapine [USAN:INN:BAN]
Loxapine (USAN/INN)
2-chloro-11-(4-methylpiperazin-1-yl)dibenzo(b,f)(1,4)oxazepine
Loxapine (water)
Loxapine (DMSO)
Adasuve (TN)
Loxapine (Standard)
Loxitane Intramuscular
Spectrum_000355
CL71,563
LOXAPINE [HSDB]
LOXAPINE [USAN]
SpecPlus_000823
8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,5]benzoxazepine
LOXAPINE [INN]
LOXAPINE [MI]
LOXAPINE [VANDF]
Prestwick0_000132
Prestwick1_000132
Prestwick2_000132
Prestwick3_000132
Spectrum2_001737
Spectrum3_001830
Spectrum5_001857
LOXAPINE [WHO-DD]
Loxitane-C Oral Suspension
Lopac0_000720
SCHEMBL94146
BSPBio_000204
BSPBio_003479
GTPL205
KBioSS_000835
DivK1c_006919
SPBio_001814
SPBio_002143
LOXAPINE [ORANGE BOOK]
BPBio1_000226
DTXCID903229
BDBM22871
KBio1_001863
KBio2_000835
KBio2_003403
KBio2_005971
KBio3_002983
N05AH01
PXB45563
HY-17390R
PDSP1_001058
PDSP2_001042
s5197
AKOS030526111
CCG-204805
CS-1105
DB00408
SDCCGSBI-0050698.P003
QTL1_000050
NCGC00021145-01
NCGC00021145-02
NCGC00021145-03
NCGC00021145-04
NCGC00021145-05
NCGC00021145-06
NCGC00021145-07
NCGC00021145-08
NCGC00021145-23
NCGC00022279-03
NCGC00022279-04
NCGC00022279-05
HY-17390
MS-24900
NS00008936
C07104
D02340
F84888
Q58614
AB00053735_15
AB00053735_16
EN300-6479125
L001085
BRD-K39915878-036-04-6
BRD-K39915878-036-05-3
BRD-K39915878-036-15-2
BRD-K39915878-036-24-4
BRD-K39915878-036-25-1
2-Chloro-11-(4-methylpiperazino)dibenz[b,f][1,4]oxazepine
8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid
13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0,3,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene
217-835-3
Solubility of 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine
When discussing the solubility of the compound 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine (C18H19ClN4O), it is essential to note the following key aspects:
In summary, while 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine exhibits intriguing solubility characteristics, specific empirical studies would be required to determine its exact solubility profile under varying conditions.