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8-Bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol

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Identification
Molecular formula
C16H16BrNO
CAS number
184198-19-4
IUPAC name
8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
State
State

At room temperature, 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol is typically a solid.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
412.50
Boiling point (Kelvin)
685.65
General information
Molecular weight
335.23g/mol
Molar mass
335.2320g/mol
Density
1.3600g/cm3
Appearence

This compound typically appears as a white to off-white crystalline solid.

Comment on solubility

Solubility of 8-Bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol

The solubility of the compound 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol (C16H16BrNO) can be influenced by its unique molecular structure. Here are some factors that typically affect its solubility:

  • Polarity: The presence of the hydroxyl group (-OH) contributes to some polarity, allowing for limited interaction with polar solvents like water.
  • Hydrophobic Regions: The aromatic and alkyl groups in the structure are more hydrophobic, suggesting that this compound may be more soluble in organic solvents such as ethanol or chloroform.
  • Temperature: Solubility can increase with temperature, so higher temperatures might enhance the dissolution of this compound in suitable solvents.

In summary, while 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol may have some solubility in water due to the hydroxyl group, it is expected to exhibit greater solubility in organic solvents due to its larger hydrophobic character. Thus, choosing the right solvent is crucial for maximizing solubility in practical applications.

Interesting facts

Interesting Facts about 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol

The compound 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol is a fascinating member of the benzazepine family, which is renowned in medicinal chemistry due to its diverse biological activities. Here are some intriguing points about this compound:

  • Structurally Unique: As a tetrahydrobenzazepine, it features a cyclic structure that plays a crucial role in its reactivity and biological functions.
  • Importance of Bromine: The presence of the bromine atom at the 8-position contributes significantly to the compound's pharmacological properties, often influencing its ability to interact with biological targets.
  • Potential Therapeutic Applications: Compounds of this type have shown promise in various areas such as anxiety relief, antipsychotic effects, and modulation of neurotransmitter activity, making them of great interest in drug development.
  • Investigative Tool: Benzazepines are frequently utilized in research to understand neuronal communication, and derivatives like this one can serve as valuable tools in pharmacological studies.
  • Discovery and Development: The synthesis of this compound may require intricate multi-step processes, showcasing the creativity and innovation required in organic chemistry.

Overall, 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol exemplifies the complex interplay of structure and function in organic compounds, particularly within the realm of medicinal chemistry. As researchers continue to explore such compounds, they open new avenues for therapeutic advances and improved understanding of biological systems.

Synonyms
99295-33-7
SKF-83566
8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol
SK&F-83566
Skf 83566
SK&F 83566
8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
1H-3-Benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-
D203LR7XUS
SK-83566
CHEMBL324017
8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepin-7-ol
1H-3-Benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-, (+/-)-
7-bromo-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol
UNII-D203LR7XUS
Biomol-NT_000061
GTPL944
BPBio1_001347
DTXSID8043816
SCHEMBL20415945
CHEBI:91747
XFTVOHWWEQGXLS-UHFFFAOYSA-N
ZDA29533
BDBM50010301
PDSP1_000503
PDSP2_000501
AKOS027307785
HY-103430A
SK83566
NCGC00025222-02
CS-0133715
G13308
BRD-A52588987-004-04-1
BRD-A52588987-004-08-2
Q27088812
8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol #
8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SKF 83566)