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Buspirone

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Identification
Molecular formula
C21H31N5O2
CAS number
36505-84-7
IUPAC name
8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
State
State

Buspirone is typically present as a solid at room temperature.

Melting point (Celsius)
190.50
Melting point (Kelvin)
463.65
Boiling point (Celsius)
-1.00
Boiling point (Kelvin)
-1.00
General information
Molecular weight
385.49g/mol
Molar mass
385.4940g/mol
Density
1.2830g/cm3
Appearence

Buspirone is a white crystalline powder.

Comment on solubility

Solubility of 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one

The solubility of the compound C21H31N5O2, also known as 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, can be quite intriguing. Various factors influence its solubility:

  • Molecular Structure: The presence of both polar and nonpolar groups in its structure affects how it interacts with solvents.
  • Polarity: The molecule contains nitrogen and oxygen atoms, which can enhance solubility in polar solvents like water.
  • Solvent Type: Solubility can vary significantly between different solvents. For example, it may dissolve better in organic solvents such as ethanol or dimethyl sulfoxide than in water.
  • Temperature: Increasing temperature often enhances solubility, particularly for solids.

As part of further investigations, it is often quoted that "a compound’s solubility is fundamentally governed by its interactions with the solvent molecules." Understanding these interactions provides insights into the solubility behavior of this intriguing compound.

In summary, the solubility of C21H31N5O2 will depend on the combination of these factors, making it essential to assess the specific conditions to draw accurate conclusions regarding its solubility.

Interesting facts

Interesting Facts about 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one

This intriguing compound, commonly known by its complex structure and lengthy name, is a member of the spiro compounds which are noted for their unique structural configuration. Here are some captivating aspects that highlight its significance in both organic chemistry and pharmaceutical applications:

  • Structural Uniqueness: The compound features a spirocyclic framework, where two rings are joined at a single atom, which contributes to its distinct spatial arrangement. This unique structure can lead to diverse biological activities.
  • Potential Biological Activity: Compounds like this one are often explored for their potential therapeutic properties. Research indicates that structurally complex compounds may exhibit interesting pharmacological effects, making them candidates for drug development.
  • Synthetic Pathways: The synthesis of such complex molecules often involves multi-step reactions, showcasing the creativity and precision required in organic synthesis. Chemists employ various techniques and reagents to assemble these intricate structures.
  • Interdisciplinary Applications: Beyond medicinal use, these types of compounds can span fields such as materials science and chemical biology. Their properties could lead to advancements in drug delivery systems or as scaffolds for new materials.

As stated by renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This compound exemplifies the essence of creativity in chemistry, sparking curiosity and innovation within scientific research.

In summary, the multifaceted nature of 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one not only presents intriguing challenges for synthetic chemists but also embodies the promise of discovering novel applications in various scientific disciplines.

Synonyms
Spiroxatrine
1054-88-2
Spiroxatrine (R 5188)
Espiroxatrina
Spiroxatrinum
Spiroxatrine [INN]
R 5188
SPIROXAMIDE
Spiroxatrinum [INN-Latin]
Espiroxatrina [INN-Spanish]
UNII-DR0QR50ALL
DR0QR50ALL
NSC 665322
NSC-665322
8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one
DTXSID3045198
CHEMBL300555
DTXCID1025198
R-5188
NSC665322
NCGC00015908-05
1,3,8-Trianaspiro(4.5)decane-4-one,8-(1,4-benzodioxan-2-ylmethyl)-1-phenyl-
Spiroxatrinum (INN-Latin)
8-(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Espiroxatrina (INN-Spanish)
CAS-1054-88-2
SR-01000075579
8-(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one
Biomol-NT_000104
GTPL53
Lopac0_001142
BPBio1_001395
SCHEMBL1255303
SCHEMBL23326247
CHEBI:91845
HMS2089G17
HMS3263F05
HMS3266D15
HMS3411K18
HMS3675K18
Tox21_110260
Tox21_501142
BDBM50020192
AKOS024458589
Tox21_110260_1
CCG-205216
LP01142
SDCCGSBI-0051109.P002
8-(1,4-Benzodioxan-2-ylmethyl)-1-phenyl-1,3,8-trianaspiro(4,5)decane-4-one
8-(1,4-benzodioxan-2-ylmethyl)-1-phenyl-1,3,8-triazaspiro(4,5)-decan-4-one
8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-4-phenyl-2,4,8-triazaspiro[4.5]decan-1-one
NCGC00015908-03
NCGC00015908-04
NCGC00015908-06
NCGC00015908-07
NCGC00015908-08
NCGC00015908-09
NCGC00024696-02
NCGC00024696-03
NCGC00024696-04
NCGC00024696-05
NCGC00261827-01
AS-85140
HY-12706
NCI60_022532
DB-108293
EU-0101142
NS00122687
S-103
L001271
Q6592066
SR-01000075579-1
SR-01000075579-3
BRD-A72483914-001-01-1
BRD-A72483914-001-02-9
BRD-A72483914-001-03-7
8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one