Skip to main content

Spirooxazine

ADVERTISEMENT
Identification
Molecular formula
C15H20N2O2
CAS number
121236-28-2
IUPAC name
8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
State
State

The compound is typically found as a crystalline solid at room temperature, suggesting it is neither a liquid nor a gas in ordinary conditions.

Melting point (Celsius)
142.00
Melting point (Kelvin)
415.20
Boiling point (Celsius)
325.50
Boiling point (Kelvin)
598.70
General information
Molecular weight
244.31g/mol
Molar mass
244.3140g/mol
Density
1.2346g/cm3
Appearence

Spirooxazine compounds are typically crystalline solids. They have a range of colors depending upon their chemical substitutions and the environment. Some can appear colorless, while others may exhibit blue, green, or violet tints in their crystalline form.

Comment on solubility

Solubility of 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one

The solubility of 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one (C15H20N2O2) can be intriguing due to its unique structural composition. This compound features both hydrophilic and hydrophobic characteristics, which significantly influence its solubility profile.

Factors Affecting Solubility

  • Polarity: Due to the presence of an oxygen atom in the cyclic structure, there is potential for hydrogen bonding with water, suggesting some level of solubility.
  • Molecular Weight: With a molecular weight of approximately 260 g/mol, this can also play a role; generally, compounds of lower molecular weight tend to be more soluble.
  • Functional Groups: The nitrogen and oxygen functional groups could enhance solubility in polar solvents, whereas the phenyl ethyl moiety may decrease solubility in non-polar solvents.

In various solvents, the solubility can be summarized as follows:

  • Water: Limited solubility is anticipated due to the bulky structure despite some potential for hydrogen bonding.
  • Organic Solvents: It may show better solubility in organic solvents such as dichloromethane or ethanol, where the hydrophobic sections of the molecule can interact favorably.

Overall, while the compound's solubility may not be exceptionally high in water, its behavior in organic mediums is likely to reveal greater solubility, making it important for applications involving organic solutions or mixed solvents.

Interesting facts

Interesting Facts about 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one

8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one is a fascinating chemical compound worthy of exploration due to its unique structure and potential applications in both medicinal and synthetic chemistry. Here are some intriguing points about this compound:

  • Unique Structural Features: This compound features a spirocyclic framework, consisting of a nitrogen-containing ring fused with another ring. This kind of structural arrangement can enhance the biological activity of compounds, contributing to their efficacy as pharmacological agents.
  • Potential Biological Activity: Compounds with diazaspiro frameworks often demonstrate various biological activities, making them of great interest in drug development. Research into similar structures has shown promise in treating conditions such as neurodegenerative diseases and various forms of cancer.
  • Versatility in Synthesis: The synthesis of this compound can be approached through multiple reaction pathways, increasing its accessibility for research purposes. The introduction of the 2-phenylethyl group additionally offers the potential for fine-tuning the compound's properties.
  • Significance in Chemical Education: Studying structures like 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one can provide chemistry students with insights into the principles of stereochemistry, reactivity, and the design of molecules tailored for specific interactions.

In conclusion, 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one stands out as a compound with unique features that spark curiosity and indicate potential for future research. As scientists continue to investigate its properties, it could become a valuable asset in the pharmaceutical landscape.

Synonyms
fenspiride
5053-06-5
Respiride
Fenspiride [INN]
Eurespal
Fenspirida
Viarespan
8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
8-Phenethyl-1-oxa-3,8-diaza-spiro[4.5]decan-2-one
Decaspiride
Fenspiridum
Fenspiridum [INN-Latin]
Fenspirida [INN-Spanish]
S983QC7HKM
Eurespal (TN)
Fenspiride (INN)
Pneumorel
8-Phenethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
FENSPIRIDE [MI]
EINECS 225-751-3
UNII-S983QC7HKM
BRN 0533332
FENSPIRIDE [WHO-DD]
DTXSID4023048
1-Oxa-3,8-diazaspiro(4,5)decan-2-one, 8-(2-phenylethyl)-
Fenspiridum (INN-Latin)
Fenspirida (INN-Spanish)
8-PHENETHYL-1-OXA-3,8-DIAZASPIRO(4.5)DECAN-2-ONE
MFCD00867054
Spectrum_001260
Prestwick0_000213
Prestwick1_000213
Prestwick2_000213
Prestwick3_000213
Spectrum2_001396
Spectrum3_001435
Spectrum4_000415
Spectrum5_001345
Lopac-F-6145
Lopac0_000496
SCHEMBL21016
BSPBio_000225
BSPBio_003170
KBioGR_000710
KBioSS_001740
DivK1c_000526
SPBio_001412
SPBio_002146
BPBio1_000249
CHEMBL576127
DTXCID703048
CHEBI:94558
HY-A0027A
KBio1_000526
KBio2_001740
KBio2_004308
KBio2_006876
KBio3_002390
R03BX01
R03DX03
NINDS_000526
1-Oxa-3,8-diazaspiro(4.5)decan-2-one, 8-(2-phenylethyl)-
BCP07882
AKOS013605285
CCG-204587
DB08979
SB37403
SDCCGSBI-0050480.P004
CAS-1151830
IDI1_000526
NCGC00015438-01
NCGC00015438-02
NCGC00015438-03
NCGC00015438-04
NCGC00015438-13
NCGC00016988-01
NCGC00162172-01
AC-25697
SBI-0050480.P003
AB00053591
CS-0013596
NS00006547
D07949
AB00053591_10
AB00053591_11
EN300-2010427
Q518027
BRD-K26739552-003-05-5
BRD-K26739552-003-14-7
BRD-K26739552-003-15-4
Z1266873958
225-751-3