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Tiotropium bromide

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Identification
Molecular formula
C19H22NO4F
CAS number
136310-93-5
IUPAC name
[8-(2-fluoroethyl)-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2,2-diphenyl-acetate
State
State
Tiotropium bromide is typically provided as a solid, often in the form of a dry powder intended for inhalation. It's a stable compound under normal conditions of use and storage.
Melting point (Celsius)
225.50
Melting point (Kelvin)
498.60
Boiling point (Celsius)
298.15
Boiling point (Kelvin)
571.30
General information
Molecular weight
472.57g/mol
Molar mass
472.5670g/mol
Density
1.6400g/cm3
Appearence

The compound appears as a white crystalline powder. It is often formulated as a bromide salt for pharmaceutical applications. The powdered form is easy to distribute and handle, commonly used in inhalation devices.

Comment on solubility

Solubility of [8-(2-fluoroethyl)-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2,2-diphenyl-acetate

The solubility of a compound can greatly influence its applications and effectiveness in various fields, such as pharmaceuticals and materials science. In the case of the compound [8-(2-fluoroethyl)-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2,2-diphenyl-acetate (C19H22NO4F), understanding its solubility properties is crucial for its potential uses.

Factors Influencing Solubility:

  • Polarity: The presence of functional groups such as -OH (hydroxyl) can increase solubility in polar solvents.
  • Temperature: Generally, solubility increases with temperature, particularly for solid solutes.
  • pH levels: For ionic compounds, changes in pH can significantly affect solubility, altering the ionization of acidic or basic groups.

In aqueous environments, the presence of the hydroxyl group suggests that this compound may exhibit moderate solubility in water, especially as a result of hydrogen bonding with water molecules. Conversely, it may also be soluble in organic solvents due to its hydrocarbon structure and diphenyl group, which could enhance interactions with non-polar solvents.

Ultimately, understanding these solubility characteristics is essential for determining how [8-(2-fluoroethyl)-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2,2-diphenyl-acetate can be utilized effectively in various applications, including drug development and material formulations.

Interesting facts

Interesting Facts about 8-(2-Fluoroethyl)-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl 2-Hydroxy-2,2-diphenyl-acetate

This compound, a fascinating member of the bicyclic amine family, has caught the attention of researchers due to its unique structural characteristics and potential applications. Here are some compelling insights about this innovative chemical:

  • Structural Complexity: The compound features a bicyclic structure, which means it contains two interconnected rings. This configuration can influence the compound's reactivity and biological activity in surprising ways.

  • Fluorine Influence: The presence of a fluoroethyl group in its structure enhances the compound's lipophilicity, which can improve its permeability through biological membranes. This could potentially enhance its effectiveness as a pharmaceutical agent.

  • Therapeutic Potential: Compounds similar to this one are often investigated for their medicinal properties. The bicyclic amine structure is known for its roles in a variety of biological systems, possibly offering insights into novel therapeutic pathways.

  • Reaction Versatility: Due to its complex structure, this compound can be synthesized through various chemical reactions, making it an interesting topic of study in synthetic organic chemistry.

  • Environmental Interaction: Understanding how compounds like this interact with environmental factors—such as solvents and biological systems—can shed light on their degradation processes and ecological impact.

In summary, 8-(2-fluoroethyl)-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl 2-hydroxy-2,2-diphenyl-acetate is not just a fascinating chemical entity due to its unique structure but also offers significant potential in medicinal chemistry and organic synthesis. Its ability to traverse biological membranes coupled with its intricate design makes it a rich subject for further research.

Synonyms
SCHEMBL8290851
DTXSID20860784
8-(2-Fluoroethyl)-3-{[hydroxy(diphenyl)acetyl]oxy}-8-methyl-8-azabicyclo[3.2.1]octan-8-ium