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6-Mercaptopurine

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Identification
Molecular formula
C5H4N4S
CAS number
50-44-2
IUPAC name
7H-purine-6-thiol
State
State

At room temperature, 6-Mercaptopurine is a solid compound. It is typically in a crystalline form with a yellow color.

Melting point (Celsius)
315.00
Melting point (Kelvin)
588.00
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.00
General information
Molecular weight
152.19g/mol
Molar mass
152.1860g/mol
Density
2.0800g/cm3
Appearence

6-Mercaptopurine appears as a yellow crystalline powder. It is practically odorless and stable in its solid form.

Comment on solubility

Solubility of 7H-purine-6-thiol

7H-purine-6-thiol, with the chemical formula C5H4N4S, exhibits notable solubility characteristics influenced by its unique molecular structure. Understanding its solubility properties is essential due to the compound's relevance in various biochemical processes.

Key points regarding the solubility of 7H-purine-6-thiol include:

  • Aqueous Solubility: Generally, 7H-purine-6-thiol may display limited solubility in water. This is primarily due to its hydrophobic purine ring structure, which can hinder interactions with water molecules.
  • Solvents: The compound tends to be more soluble in organic solvents, such as ethanol or dimethyl sulfoxide (DMSO), which can accommodate the compound's aromatic characteristics.
  • Influence of pH: Changes in pH can also affect solubility; at certain pH levels, the ionization state of the thiol group may enhance solubility in polar solvents.

In summary, while 7H-purine-6-thiol may not be readily soluble in water, its solubility can improve significantly in organic solvents and under varying pH conditions. Understanding these solubility nuances is crucial for applications in research and the development of pharmaceuticals where solubility can impact bioavailability.

Interesting facts

Interesting Facts about 7H-Purine-6-Thiol

7H-purine-6-thiol, often referred to as a significant compound within the purine family, showcases a unique structure and several intriguing properties that make it a subject of interest among chemists and biochemists alike. Here are some noteworthy points about this compound:

  • Biological Relevance: Purines are essential components of nucleotides, which are the building blocks of DNA and RNA. As such, 7H-purine-6-thiol can potentially play a role in cellular processes and genetic material maintenance.
  • Unusual Functional Group: The presence of a thiol group (-SH) in the 6-position is notable because sulfur is known for its versatility in chemical bonding. This could lead to interesting reactivity in various biochemical pathways.
  • Potential Applications: Compounds like 7H-purine-6-thiol are often studied for their potential applications in drug discovery, especially as anti-cancer agents or in therapies targeting genetic diseases.
  • Research Interest: Due to its unique properties, this compound has been the focus of numerous studies aiming to explore sulfur’s role in biological systems, paving the way for advancements in medicinal chemistry.

As one delves deeper into the world of 7H-purine-6-thiol, it becomes evident that understanding such compounds can illuminate the complexities of biochemical interactions and lead to significant breakthroughs in various fields of science.