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2-Mercaptoadenine

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Identification
Molecular formula
C5H5N5S
CAS number
1201-31-6
IUPAC name
7H-purine-2-thiol
State
State

At room temperature, 2-Mercaptoadenine is in a solid state, typically presenting as crystalline powder. It is stable under normal conditions of use and storage.

Melting point (Celsius)
299.00
Melting point (Kelvin)
572.00
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.00
General information
Molecular weight
151.20g/mol
Molar mass
151.1950g/mol
Density
1.6500g/cm3
Appearence

The compound typically appears as a crystalline solid that can be white to yellowish in color. It is generally fine and powdery in texture. Due to its chemical structure, it is likely to have a distinct odor that can be characterized as sulfur-like, akin to other thiols.

Comment on solubility

Solubility of 7H-purine-2-thiol (C5H5N5S)

The solubility characteristics of 7H-purine-2-thiol, a compound featuring a thiol functional group, are particularly intriguing and can be influenced by several factors:

  • Polarity: 7H-purine-2-thiol contains polar functional groups, which enhances its solubility in polar solvents like water.
  • Hydrogen bonding: The presence of the thiol (-SH) group allows for hydrogen bonding with water molecules, further contributing to its solubility.
  • pH sensitivity: The solubility of this compound can vary with changes in pH, potentially affecting its ionization state.

Typically, compounds with thiol groups are known to be more soluble in aqueous solutions and can readily dissolve when mixed with alcohols or other polar solvents. It is important to note that while its solubility in water is favorable, this may not be the case in nonpolar solvents, where the compound may exhibit limited solubility.

In summary, 7H-purine-2-thiol demonstrates **moderate to high solubility** in polar solvents, making it an interesting compound for further exploration in various chemical contexts.

Interesting facts

Interesting Facts About 7H-Purine-2-thiol

7H-purine-2-thiol is an intriguing compound that belongs to the purine family, which plays a crucial role in various biological processes. This compound, characterized by its sulfur-containing thiol group, has garnered significant attention in both medicinal chemistry and biochemistry.

Key Characteristics and Applications

  • Biological Importance: Purines are essential components of nucleic acids, which are vital for genetic information storage and transfer. 7H-purine-2-thiol is often studied for its role in cellular metabolism and function.
  • Pharmaceutical Potential: Research has indicated that derivatives of purines, including 7H-purine-2-thiol, may exhibit interesting pharmacological properties, particularly as anti-cancer agents due to their ability to interfere with purine metabolism in rapidly dividing cells.
  • Antioxidant Activity: This compound may also demonstrate antioxidant behavior, which can help protect cells from oxidative stress—a contributing factor in various diseases.

Research Insights

  • Studies have shown that modifying the thiol group of purines can lead to improved activity against specific biological targets.
  • The potential for 7H-purine-2-thiol in the development of new therapeutic agents is a hot topic, with ongoing research aimed at unlocking its full potential.

As the renowned chemist, Sir Derek H.R. Barton said, "Chemistry is the science of matter, but I see it as the science of change." The exploration of compounds like 7H-purine-2-thiol exemplifies this change, as researchers delve into its properties and applications, paving the way for innovative treatments and a deeper understanding of biological processes.