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Adenine

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Identification
Molecular formula
C5H5N5
CAS number
73-24-5
IUPAC name
7H-purin-6-amine
State
State

At room temperature, adenine is a solid. It is stable under normal temperatures and pressures.

Melting point (Celsius)
360.00
Melting point (Kelvin)
633.00
Boiling point (Celsius)
800.00
Boiling point (Kelvin)
1 073.00
General information
Molecular weight
135.13g/mol
Molar mass
135.1270g/mol
Density
1.5900g/cm3
Appearence

Adenine appears as a white to almost white crystalline powder. It has no significant aroma or color, making it easily recognizable in its pure form. It can also be found as solid crystals, which may vary in size depending on the method of crystallization.

Comment on solubility

Solubility of 7H-purin-6-amine (C5H5N5)

7H-purin-6-amine, also known as adenine, exhibits interesting solubility characteristics which are essential for its biological functions. Here are some key insights into its solubility:

  • Water Solubility: Adenine is relatively soluble in water, with a solubility limit of approximately 40 g/L at room temperature. This property is vital for its role in various biochemical processes.
  • Solvent Compatibility: It is soluble in a few organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF), but poorly soluble in non-polar solvents.
  • Temperature Dependency: Solubility can increase with temperature; thus, heating the solution may enhance the dissolution rate.
  • pH Influence: The solubility of adenine is influenced by the pH of the solution. In strongly acidic or alkaline conditions, its solubility may vary.

In summary, the solubility of C5H5N5 is not only an important factor to consider in laboratory settings, but it also plays a crucial role in its biological functionality. As with many compounds, understanding its solubility can provide insights into how it behaves in various chemical environments.

Interesting facts

Interesting Facts about 7H-purin-6-amine

7H-purin-6-amine, also known as adenine, is a crucial nucleotide base that plays a significant role in cellular functions. Here are some fascinating insights into this compound:

  • Key Component of Nucleotides: Adenine is one of the four primary nucleobases in the nucleic acids DNA and RNA, alongside cytosine, guanine, and thymine (in DNA). It pairs with thymine in DNA and with uracil in RNA, facilitating the storage and transmission of genetic information.
  • Energy Molecule: This compound is also a part of adenosine triphosphate (ATP), the energy currency of the cell. ATP is essential for various biological processes, including muscle contraction, nerve impulse propagation, and biosynthesis.
  • Role in Metabolism: Adenine participates in the formation of important coenzymes such as NAD (nicotinamide adenine dinucleotide), which plays a critical role in metabolic reactions and energy production.
  • Systems of Life: Beyond its genetic functions, adenine is involved in signaling pathways and is a component of important molecules like coenzyme A and cyclic AMP, which mediate various physiological processes.
  • Medical Relevance: Research into adenine has significant implications for understanding diseases related to energy metabolism, and it has even been studied for its potential roles in cancer and aging.

In summary, adenine is not just a simple nitrogenous base; it is a vital compound that supports life at the molecular level. Its contributions range from genetic information to energy transfer, making it a fascinating subject of study in biochemistry and molecular biology.

Synonyms
adenine
73-24-5
6-Aminopurine
1H-Purin-6-amine
9H-Purin-6-amine
7H-Purin-6-amine
Vitamin B4
Adenin
Adeninimine
Leuco-4
6-Amino-1H-purine
6-Amino-3H-purine
6-Amino-7H-purine
6-Amino-9H-purine
1,6-Dihydro-6-iminopurine
Purine, 6-amino-
3,6-Dihydro-6-iminopurine
USAF CB-18
1H-Purine, 6-amino
Adenine [JAN]
ADE
9H-Purine, 1,6-dihydro-6-imino-
3H-Purin-6(7H)-imine
NSC 14666
CCRIS 2556
CHEBI:16708
1H-Purine-6-amine
AI3-50679
MFCD00041790
NSC-14666
66224-66-6
71660-29-2
EINECS 200-796-1
7H-Purin-6-amine (9CI)
UNII-JAC85A2161
9H-Purine-6-amine
9H-purin-6-ylamine
134434-48-3
DTXSID6022557
Adenine [USP:JAN]
JAC85A2161
1H-Purine, 6-amino-
6H-Purin-6-imine, 3,9-dihydro-, (Z)- (9CI)
CHEMBL226345
DTXCID502557
134434-49-4
134454-76-5
6,7-dihydro-3H-purin-6-imine
NSC14666
6H-Purin-6-imine, 1,7-dihydro-, (Z)- (9CI)
6H-Purin-6-imine, 1,9-dihydro-, (E)- (9CI)
6H-Purin-6-imine, 3,7-dihydro-, (Z)- (9CI)
(Z)-3,9-Dihydro-6H-purin-6-imine
134461-75-9
Adenine (USP:JAN)
NCGC00094856-01
Pedatisectine B
ADENINE (MART.)
ADENINE [MART.]
ADENINE (USP-RS)
ADENINE [USP-RS]
Adenine; 7H-purin-6-amine
Vitamin B 4
ADENINE (EP MONOGRAPH)
ADENINE (USP IMPURITY)
ADENINE [EP MONOGRAPH]
ADENINE [USP IMPURITY]
4, Vitamin B
B 4, Vitamin
ADENINE (USP MONOGRAPH)
ADENINE [USP MONOGRAPH]
Adenine, United States Pharmacopeia (USP) Reference Standard
adenine-ring
CAS-73-24-5
Adenine (8CI)
Adenine (JAN/USP)
SR-05000001754
1H-purin-6(9H)-imine
6-Aminopurine; Vitamin B4
1H-Purin-6-amine (9CI)
3H-Purin-6-amine (9CI)
6-Purinylamine
3h-adenine
6-amino purine
6-amino-Purine
purin-6-amine
1jys
1nli
1wei
2pqj
3kpv
[3H]adenine
Adenine, 1
Adenine,(S)
Adenine (Standard)
ALBB-005925
Adenine1546
7H-purin-6-ylamine
71660-30-5
(S)-Norfluoxetine-d5
9H-Purin-6-yl-amin
KINETIN_met004
Spectrum_001106
2p8n
starbld0001134
9H-Purin-6-yl-amine
ADENINE [VANDF]
SpecPlus_000535
Adenine, >=99%
9H-Purin-6-amine #
ADENINE [MI]
Spectrum2_000583
Spectrum3_000616
Spectrum4_001891
Spectrum5_000542
ADENINE [WHO-DD]
6-Aminopurine;Vitamin B4
bmse000060
bmse000861
bmse000995
Epitope ID:140097
Adenine, cell culture grade
SCHEMBL8110
Oprea1_057274
US9138393, Adenine
US9144538, Adenine
BSPBio_002152
KBioGR_002447
KBioGR_002562
KBioSS_001586
KBioSS_002571
MLS001066342
DivK1c_006631
SPECTRUM1500807
SPBio_000426
GTPL4788
9H-Purine,6-dihydro-6-imino-
BDBM33218
HY-B0152R
KBio1_001575
KBio2_001586
KBio2_002562
KBio2_004154
KBio2_005130
KBio2_006722
KBio2_007698
KBio3_001652
KBio3_003040
Adenine 100 microg/mL in Water
cMAP_000085
BCPP000433
BDBM181146
HMS1921I14
HMS2092K20
HMS2269I04
Pharmakon1600-01500807
BCP02865
HY-B0152
JEA92352
Tox21_111348
Tox21_302108
BBL007925
BDBM50582699
CCG-38506
NSC757793
s1981
STK387542
WLN: T56 BM DN FN HNJ IZ
Adenine, low endotoxin ?0.2 EU/mg
AKOS000118903
AKOS005171607
Tox21_111348_1
AC-2028
BCP9000233
CS-1984
DB00173
FA02660
NSC-757793
SDCCGMLS-0066584.P001
NCGC00094856-02
NCGC00094856-03
NCGC00094856-05
NCGC00255120-01
AS-11841
BL008313
NCI60_000998
SMR000471871
ADENOSINE IMPURITY A [EP IMPURITY]
SBI-0052324.P002
Adenine, Vetec(TM) reagent grade, >=99%
DB-013503
DB-186696
DB-264100
A0149
NS00010868
EN300-21472
Adenine, suitable for cell culture, BioReagent
C00147
D00034
Q15277
AB00052833-18
AB00052833-19
AB00052833_20
AB00052833_22
AB00052833_23
AB00052833_24
SR-05000001754-1
SR-05000001754-2
BRD-K26060080-001-10-1
BRD-K26060080-001-11-9
BRD-K26060080-003-07-3
BRD-K26060080-065-05-6
Adenine, BioReagent, plant cell culture tested, >=99%
Adenine, European Pharmacopoeia (EP) Reference Standard
F0001-1848
Z104498572
6379C0E0-C1BB-4087-96C5-1DE281B8EA4C
Adenine, Pharmaceutical Secondary Standard; Certified Reference Material
InChI=1/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10
200-796-1