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7,8,9,10-Tetrahydrobenzo[a]pyrene-7,8,9-triol

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Identification
Molecular formula
C20H16O3
CAS number
47260-65-7
IUPAC name
7,8,9,10-tetrahydrobenzo[a]pyrene-7,8,9-triol
State
State

At room temperature, this compound is generally found in a solid state, due to its relatively high melting point.

Melting point (Celsius)
126.80
Melting point (Kelvin)
399.95
Boiling point (Celsius)
461.20
Boiling point (Kelvin)
734.35
General information
Molecular weight
292.35g/mol
Molar mass
292.3480g/mol
Density
1.3400g/cm3
Appearence

Typically appearing as a crystalline solid with a potential off-white to pale yellowish color. The exact appearance may vary based on the specific conditions and purity of the compound.

Comment on solubility

Solubility of 7,8,9,10-tetrahydrobenzo[a]pyrene-7,8,9-triol

The solubility of 7,8,9,10-tetrahydrobenzo[a]pyrene-7,8,9-triol (C20H16O3) is an intriguing topic of discussion, particularly due to its complex molecular structure. Here are some key points regarding its solubility:

  • Hydrophilicity vs. Hydrophobicity: Given the presence of multiple hydroxyl (–OH) groups in the compound, there is potential for increased hydrophilicity, enhancing solubility in polar solvents.
  • Solvent Interactions: The solubility of this compound may significantly depend on the solvent type. For instance, it may dissolve well in:
    • Polar solvents like water or methanol due to hydrogen bonding.
    • Organic solvents like acetonitrile or dimethyl sulfoxide (DMSO).
  • Concentration Factors: Factors such as temperature and concentration can also play a crucial role—higher temperatures often enhance solubility.
  • Environmental Impact: Understanding solubility is vital for assessing the environmental impact and bioavailability, as low solubility could lead to accumulation in biological systems and ecosystems.

In conclusion, while 7,8,9,10-tetrahydrobenzo[a]pyrene-7,8,9-triol presents characteristics that may support solubility, actual behavior can vary significantly based on external conditions and solvent choices. As we explore its applications and implications, a closer look at its solubility profile is essential.

Interesting facts

Interesting Facts About 7,8,9,10-tetrahydrobenzo[a]pyrene-7,8,9-triol

7,8,9,10-tetrahydrobenzosup>[a]pyrene-7,8,9-triol, commonly referred to in scientific literature, is a fascinating polycyclic aromatic hydrocarbon (PAH) that arises from the metabolic processes of various other PAHs. Here are some intriguing insights:

  • Environmental Relevance: This compound is of considerable interest in environmental chemistry due to its formation from the thermal degradation of organic matter, notably from the combustion of fossil fuels and tobacco. It serves as a marker for **toxic compounds** in polluted settings.
  • Tumorigenesis Studies: Research has indicated that derivatives of benzo[a]pyrene, including its tetrahydro forms, can interact with biological macromolecules. These interactions can lead to mutations, thereby playing a crucial role in the study of **cancer biology** and mechanisms of tumorigenesis.
  • Solubility and Reactivity: As a triol, its hydroxyl groups enhance its reactivity compared to its non-hydroxylated counterparts. This feature has made it a subject of study in organic synthesis and **materials science**.
  • Analytical Techniques: Its analysis often employs advanced techniques such as gas chromatography-mass spectrometry (GC-MS), which allows for sensitive detection of trace amounts in environmental samples, essential for understanding **ecotoxicology**.
  • Potential Therapeutic Insights: Emerging research suggests that understanding the metabolic pathways of compounds like 7,8,9,10-tetrahydrobenzosup>[a]pyrene-7,8,9-triol could lead to novel therapeutic strategies against the adverse effects associated with PAH exposure.

In summary, the study of 7,8,9,10-tetrahydrobenzosup>[a]pyrene-7,8,9-triol not only sheds light on environmental processes but also contributes significantly to our understanding of **biochemistry**, **toxicology**, and potential pathways for therapeutic intervention. Its multifaceted nature makes it a valuable candidate for ongoing research across various scientific disciplines.

Synonyms
71697-30-8
7,8,9,10-tetrahydrobenzo[pqr]tetraphene-7,8,9-triol
Benzo(a)pyrene-7,8,9-triol, 7,8,9,10-tetrahydro-
7,8,9,10-tetrahydrobenzo[a]pyrene-7,8,9-triol
DTXSID30992308
PD037830