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SCH-23390

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Identification
Molecular formula
C18H21NO2
CAS number
67287-54-1
IUPAC name
7,8-dimethoxy-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine
State
State

At room temperature, SCH-23390 typically appears as a solid. It is stable under ordinary conditions of use and storage, maintaining its structure and properties without significant degradation.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
525.30
Boiling point (Kelvin)
798.45
General information
Molecular weight
311.39g/mol
Molar mass
311.3850g/mol
Density
1.2063g/cm3
Appearence

The compound appears as a white crystalline powder.

Comment on solubility

Solubility of 7,8-Dimethoxy-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine

The solubility of 7,8-dimethoxy-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine (C18H21NO2) can be quite intriguing, as it is influenced by several factors:

  • Polarity: The presence of methoxy groups in this compound contributes to its overall polarity, potentially aiding in solubility in polar solvents.
  • Structural Characteristics: The benzazepine ring system adds complexity; therefore, solubility can vary depending on the solvent type.
  • Hydrogen Bonding: The nitrogen atom in the structure may engage in hydrogen bonding, enhancing solubility in protic solvents like water.

It is important to note that solubility can range significantly based on conditions:

  1. If tested in water, lower solubility might be observed due to hydrophobic regions of the compound.
  2. In organic solvents, such as ethanol or dimethyl sulfoxide (DMSO), increased solubility is likely due to favorable interactions.

Thus, the solubility profile of this compound can be summarized as solvent-dependent, highlighting the need for specific solvent selection to achieve solubility in practical applications. Understanding these factors is crucial for effectively utilizing this compound in research and industry.

Interesting facts

Discovering 7,8-Dimethoxy-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine

7,8-Dimethoxy-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine is a fascinating compound that highlights the intricate nature of organic chemistry. As we delve into its structure and properties, several interesting aspects come to light:

  • Complex Structure: This compound features a multi-ring structure, typical of many alkaloids, which often exhibit significant biological activity.
  • Potential Therapeutic Uses: Compounds like this tetrahydro-benzazepine derivative have been investigated for their potential medicinal properties, including neuropharmacological effects. They might influence the central nervous system, making them candidates for further research in treating neurological disorders.
  • Dimethoxy Functionality: The presence of the methoxy groups at positions 7 and 8 is particularly noteworthy, as they can enhance the compound's lipophilicity, potentially affecting its interactions with biological membranes.
  • Synthetic Interest: Chemists are interested in synthesizing such compounds due to the challenge and skill required in constructing their complex molecular frameworks, often involving detailed reaction mechanisms.
  • Class of Compounds: This compound belongs to a broader class of benzazepines, which are structurally related to alkaloids and have been shown to exhibit various biological activities, including anti-inflammatory and analgesic properties.

As you can see, 7,8-dimethoxy-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine not only embodies a captivating arrangement of atoms but also serves as a reminder of the profound impact that synthetic organic chemistry can have on pharmaceuticals and therapeutic applications. Their study enriches our understanding of organic compounds and their potential to improve human health.

Synonyms
Trimopam
20012-08-2
Sch-12679
7,8-Dimethoxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
N-Methyl-1-phenyl-7,8-dimethoxy-2,3,4,5-tetrahydro-3-benzazepine
CHEMBL343569
7,8-dimethoxy-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine
7,8-dimethoxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
2,3,4,5-Tetrahydro-7,8-dimethoxy-3-methyl-1-phenyl-1H-3-benzazepine
d-7,8-Dimethoxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
1H-3-Benzazepine, 2,3,4,5-tetrahydro-7,8-dimethoxy-3-methyl-1-phenyl-
1H-3-Benzazepine, 2,3,4,5-tetrahydro-7,8-dimethoxy-3-methyl-1-phenyl-, (+)-
SCHEMBL11704977
DTXSID80860568
ICPHJSKVAZMKIV-UHFFFAOYSA-N
BDBM50067817
AKOS040754265
NCGC00162352-01
DB-229596
Q18394827
N-methyl-1-phenyl-7,8-dimethoxy-2,3,4,5-tetra-hydro-3-benzazepine
7,8-dimethoxy-3-methyl-1-phenyl-2,3,4,5- tetrahydro-1H-3-benzazepine