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7-nitroindazole

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Identification
Molecular formula
C7H5N3O2
CAS number
2942-88-3
IUPAC name
7-nitro-1H-indazole
State
State

At room temperature, 7-Nitroindazole is a solid.

Melting point (Celsius)
196.00
Melting point (Kelvin)
469.15
Boiling point (Celsius)
395.00
Boiling point (Kelvin)
668.15
General information
Molecular weight
177.13g/mol
Molar mass
177.1530g/mol
Density
1.4410g/cm3
Appearence

7-Nitroindazole is a yellow crystalline solid. It is typically characterized by its distinct color and solid crystalline form when observed at room temperature.

Comment on solubility

Solubility of 7-nitro-1H-indazole

7-nitro-1H-indazole, with the chemical formula C7H5N3O2, presents interesting solubility characteristics that could impact its applicability in various chemical and pharmaceutical contexts.

General Solubility Insights

  • Polarity: The presence of a nitro group (–NO2) contributes to the polar character of this compound, influencing its solubility in different solvents.
  • Solvent Compatibility: It is generally more soluble in polar solvents such as water and methanol compared to non-polar solvents like hexane.
  • Temperature Influence: Like many organic compounds, the solubility of 7-nitro-1H-indazole can increase with temperature, allowing for improved dissolution in higher temperature solutions.

Practical Considerations

When considering the practical usage of 7-nitro-1H-indazole, the following points may be relevant:

  • Stability: The solubility can be influenced by the stability of the compound in the chosen solvent, where degradation could occur in certain conditions.
  • pH Effect: Solubility may vary with pH adjustments; alkaline conditions can sometimes enhance solubility for compounds with acidic functional groups.
  • Concentration Limits: It is essential to consider the solubility limit when preparing solutions to avoid precipitation during use.

In summary, the solubility of 7-nitro-1H-indazole is a crucial parameter that influences its utility in applications, and careful consideration of solvent choice, temperature, and pH is paramount for optimal results.

Interesting facts

Interesting Facts about 7-Nitro-1H-Indazole

7-Nitro-1H-indazole is a fascinating compound that features prominently in various fields of chemistry and pharmacology. Here are some key highlights about this intriguing compound:

  • Structural Interest: The compound belongs to the indazole class, which is known for its unique bicyclic structure. This structure contributes to its interesting chemical reactivity and stability.
  • Biological Significance: Research suggests that 7-nitro-1H-indazole possesses potential biological activities, making it a candidate for further investigation in drug development. It has been studied for its effects on various biological processes, including its potential as a neurotransmitter modulator.
  • Research Applications: This compound has applications in the synthesis of other chemical entities, and scientists often utilize it as a building block in the development of new pharmaceuticals. Its nitro group offers opportunities for further chemical modification and functionalization.
  • Analytical Techniques: 7-Nitro-1H-indazole can be analyzed and characterized using various techniques, including NMR, mass spectrometry, and infrared spectroscopy. Such analytical methods are essential for understanding its properties and interactions.
  • Chemical Behavior: The nitro substituent on the indazole ring is a point of interest in reactivity studies. It can participate in various chemical reactions, including nucleophilic substitutions and reductions, providing insight into the reactivity patterns of similar compounds.

The exploration of 7-nitro-1H-indazole serves as an excellent reminder of the complexity and beauty of organic chemistry. As researchers delve deeper into its properties and applications, exciting discoveries may emerge, showcasing the potential of this compound in scientific advancement.

Synonyms
7-nitroindazole
7-Nitro-1H-indazole
2942-42-9
1H-Indazole, 7-nitro-
7-NI
7-nitro-indazole
CCRIS 3309
UX0N37CMVH
EINECS 220-934-4
MFCD00022789
NSC 72843
BRN 0006809
7-Nitro-2H-indazole
NSC-72843
NITROINDAZOLE, 7-
MLS000028452
CHEMBL247378
DTXSID30183638
SMR000058266
7NI
SR-01000075512
UNII-UX0N37CMVH
7-Nitroisoindazole
Tocris-0602
Opera_ID_1690
Spectrum2_001715
Spectrum3_001980
Lopac-N-7778
7-Nitroindazole (7-NI)
7-Nitroindazole, >=98%
NCIOpen2_000477
Lopac0_000839
BSPBio_003580
909091-71-0
MLS001074098
MLS001424158
SCHEMBL216995
SPECTRUM1505342
SPBio_001730
GTPL5127
SCHEMBL13039512
CHEBI:40287
KBio3_002963
PQCAUHUKTBHUSA-UHFFFAOYSA-
DTXCID70106129
HMS2052E13
HMS2235A13
HMS3262H19
HMS3266B05
HMS3370D01
HMS3394E13
HMS3411I16
HMS3675I16
HMS3886O10
BCP27530
CS-D0829
NSC72843
Tox21_500839
BDBM50209245
CCG-39508
HSCI1_000055
s5542
STK776289
AKOS001740210
AC-3118
CCG-101113
DB02207
LP00839
NC00363
PB17062
SDCCGSBI-0050816.P002
NCGC00015750-01
NCGC00015750-02
NCGC00015750-03
NCGC00015750-04
NCGC00015750-05
NCGC00015750-06
NCGC00015750-07
NCGC00015750-08
NCGC00015750-09
NCGC00015750-10
NCGC00015750-15
NCGC00021621-02
NCGC00021621-04
NCGC00021621-05
NCGC00021621-06
NCGC00021621-07
NCGC00261524-01
HY-69019
PD000923
SY003892
DB-012306
DB-400223
EU-0100839
N0827
NS00028691
EN300-71900
8P-906
M02148
N 7778
A819914
A03-0007
Q4642875
SR-01000075512-1
SR-01000075512-3
BRD-K04430056-001-02-9
BRD-K04430056-001-17-7
BRD-K04430056-236-01-3
BRD-K04430056-236-02-1
Z381673562
InChI=1/C7H5N3O2/c11-10(12)6-3-1-2-5-4-8-9-7(5)6/h1-4H,(H,8,9)
220-934-4