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Mitiglinide

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Identification
Molecular formula
C19H22N2O
CAS number
145375-44-4
IUPAC name
(7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl)methanol
State
State

Mitiglinide is in a solid state at room temperature. It is typically stable and used in oral pharmaceutical formulations.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
470.00
Boiling point (Kelvin)
743.15
General information
Molecular weight
317.42g/mol
Molar mass
317.4150g/mol
Density
1.2700g/cm3
Appearence

Mitiglinide appears as a white to off-white powder. As a crystalline solid, it has no significant odor and is often synthesized in fine particulate form for pharmaceutical uses.

Comment on solubility

Solubility Overview

The solubility characteristics of the compound (7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl)methanol, with the chemical formula C19H22N2O, can be quite intriguing. Understanding its solubility helps in predicting its behavior in various environments and applications.


Key Solubility Insights

  • Polarity: Due to the presence of the hydroxyl group (-OH) in its structure, this compound exhibits some degree of polarity.
  • Solvent Interactions: It is likely to dissolve well in polar solvents such as water and methanol, while demonstrating limited solubility in non-polar solvents like hexane.
  • pH Dependency: The solubility may vary significantly with changes in pH, particularly since the presence of nitrogen atoms can interact with hydrogen ions.
  • Temperature Influence: Increased temperature may enhance solubility, a common feature among many organic compounds.

In summary, while specific quantitative solubility data on (7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl)methanol may not be readily available, the aforementioned factors play a crucial role in determining its behavior in solution. As with many compounds, the interplay between structure and solvent characteristics will greatly dictate its overall solubility profile. Understanding these aspects is essential for both experimental work and potential application development.

Interesting facts

Interesting Facts about (7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl)methanol

This fascinating compound belongs to the family of indole derivatives, which are well-regarded in the field of medicinal chemistry due to their diverse biological activities. Here are some intriguing aspects of this compound:

  • Structural Complexity: The compound features a unique indoloquinoline structure, which is characterized by a fusion of indole and quinoline systems. This complexity contributes to its potential biological activities.
  • Biological Significance: Compounds of this type often exhibit a range of pharmacological properties, making them subjects of interest for various therapeutic applications, including anti-cancer, anti-inflammatory, and neuroprotective effects.
  • Research Interest: Scientists have been exploring the potential of indoloquinoline derivatives in the treatment of neurological disorders, as they may facilitate neurogenesis and possess antioxidant properties.
  • Synthetic Challenges: The synthesis of this compound can be intricate, often requiring multi-step processes that may utilize advanced organic reaction mechanisms to achieve the desired structure with high precision.
  • Structure-Activity Relationship (SAR): The relationship between the chemical structure and biological activity is a key aspect of ongoing research, as modifications to the indole or quinoline components could lead to enhanced efficacy or reduced side effects.

In summary, (7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl)methanol exemplifies the intricate interplay between structure and biological function, making it a compelling target for further investigation in the field of drug discovery. As research continues, the insights gained from studying this compound could potentially lead to significant advancements in therapeutic strategies.

Synonyms
602-85-7
Lysergole
NSC 196867
LOL
Ergoline, 9,10-didehydro-8-hydroxymethyl-6-methyl-
Ergoline-8.beta.-methanol, 9,10-didehydro-6-methyl-
Ergoline-8-methanol, 9,10-didehydro-6-methyl-, (8.beta.)-
Oprea1_812943
(6-Methyl-9,10-didehydroergolin-8-yl)methanol-, (8.beta.)-
9,10-Didehydro-6-methyl-8-hydroxymethylergoline, (8.beta.)-
SCHEMBL257961
DTXSID40975627
NSC196867
AKOS030254986
NSC-196867
DB-053583
Ergoline,10-didehydro-8-hydroxymethyl-6-methyl-
Ergoline-8.beta.-methanol,10-didehydro-6-methyl-
L001137
WLN: T C6656 1A P GN LM CUTT&&T E1Q G
Ergoline-8-methanol,10-didehydro-6-methyl-, (8.beta.)-