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Guaiol

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Identification
Molecular formula
C15H26
CAS number
489-86-1
IUPAC name
7-isopropyl-1,4-dimethyl-azulene
State
State
Guaiol typically exists as a solid at room temperature, forming crystalline structures.
Melting point (Celsius)
92.00
Melting point (Kelvin)
365.15
Boiling point (Celsius)
92.00
Boiling point (Kelvin)
365.15
General information
Molecular weight
204.35g/mol
Molar mass
204.3510g/mol
Density
0.9403g/cm3
Appearence

Guaiol is a crystalline solid with a distinct appearance typical of many natural sesquiterpenes often containing a clear to pale yellow coloration.

Comment on solubility

Solubility of 7-isopropyl-1,4-dimethyl-azulene

The solubility of 7-isopropyl-1,4-dimethyl-azulene (C15H26) is a nuanced topic that reflects the unique structure and hydrophobic characteristics of this compound. Its solubility properties can be generally outlined as follows:

  • Nonpolar Characteristics: Due to its alkyl substituents and aromatic structure, 7-isopropyl-1,4-dimethyl-azulene tends to exhibit nonpolar behavior, making it more soluble in organic solvents than in polar solvents.
  • Solvent Compatibility: This compound is expected to dissolve well in nonpolar solvents such as hexane, toluene, and benzene.
  • Limited Water Solubility: As a general rule, the presence of multiple alkyl groups and the aromatic system contributes to very low solubility in water, in line with “like dissolves like” principle.

When considering the solubility of this compound, it’s essential to remember that the specific conditions, such as temperature and the presence of other solutes, can affect the degree of solubility. Overall, while 7-isopropyl-1,4-dimethyl-azulene may not readily dissolve in aqueous solutions, its compatibility with organic solvents opens avenues for various applications in organic chemistry and material science.

Interesting facts

Interesting Facts about 7-Isopropyl-1,4-Dimethyl-Azulene

7-Isopropyl-1,4-dimethyl-azulene is a fascinating organic compound with unique structural and functional characteristics. Its vibrant structure is composed of an azulene skeleton, known for its distinct blue color, which sets it apart in the world of organic chemistry.

Characteristics of Azulene Compounds

Azulenes are remarkable for several reasons:

  • Distinct Color: The presence of conjugated double bonds gives azulenes their signature blue hue, making them visually striking.
  • Geometric Isomerism: Due to their unique configurations, compounds like 7-isopropyl-1,4-dimethyl-azulene exhibit interesting geometric isomerism, which can lead to different physical and chemical properties.
  • Biological Activity: Some azulenes have demonstrated biological activities, including anti-inflammatory and antimicrobial effects.

Applications and Uses

This specific compound, with its branched alkyl groups, could find potential applications in:

  • Organic Synthesis: The unique structure may allow it to act as an intermediate in the synthesis of more complex organic molecules.
  • Material Science: Compounds like 7-isopropyl-1,4-dimethyl-azulene can contribute to the development of new dyes, pigments, or polymers.

Research and Studies

Research into azulenes often explores their photophysical properties and reactivity:

  • Stable Radicals: Studies have indicated that some azulene derivatives can form stable radicals, which is a topic of interest in physical chemistry and materials science.
  • Environmental Impact: Understanding the behavior and stability of such compounds can also provide insights into environmental chemistry, particularly in relation to organic pollutants.

In conclusion, 7-isopropyl-1,4-dimethyl-azulene is not just a chemical compound; it embodies an intersection of beauty and science, presenting intriguing possibilities for future research and applications. Its unique properties make it a compound of interest to both chemists and materials scientists alike.

Synonyms
guaiazulene
489-84-9
1,4-Dimethyl-7-isopropylazulene
Azulon
7-Isopropyl-1,4-dimethylazulene
Vetivazulen
Azunol
Kessazulen
Purazulen
Silazulon
Uroazulen
S-Guaiazulene
guaiazulen
Eucazulen
Guajazulene
Guiazulene
Cuteazul
Gurjunazulen
Azulen-beris
1,4-dimethyl-7-propan-2-ylazulene
3,8-Dimethyl-5-(2-propyl)azulene
Azulene, 1,4-dimethyl-7-(1-methylethyl)-
Vaumigan
1,4-Dimethyl-7-(1-methylethyl)azulene
Eucazulene
Azulol
hepatoprotectant
1,4-dimethyl-7-(propan-2-yl)azulene
Azunol (TN)
Kessazulene
UNII-2OZ1K9JKQC
7-isopropyl-1,4-dimethyl-azulene
NSC 4714
EINECS 207-701-2
Azulene, 7-isopropyl-1,4-dimethyl-
1,3,5,7,9-Guaiapentaene
AZ-8 beris
BRN 1365001
CHEBI:5550
DTXSID7045996
AZULENE, 1,4-DIMETHYL-7-ISOPROPYL-
NSC-4714
GUAIAZULENE [MI]
2OZ1K9JKQC
GUAIAZULENE [MART.]
1,4-Dimethyl-7-isopropylazulene (JAN)
GUAIAZULENE [WHO-DD]
DTXCID5025996
1, 4-Dimethyl-7-isopropylazulene
1,4-Dimethyl-7-isopropyl-Azulene
4-05-00-01751 (Beilstein Handbook Reference)
MFCD00003811
NCGC00095836-02
1,4-dimethyl-7-(1-methylethyl)-azulene
1,4-Dimethyl-7-(1-methyl)-azulene (azulon)
1,4-Dimethyl-7-(1-methylethyl)azulene, 9CI
1,4-DIMETHYL-7-ISOPROPYLAZULENE [JAN]
GUAIAZULENE (MART.)
GUAIAZULENE (CONSTITUENT OF CHAMOMILE) [DSC]
CAS-489-84-9
7-isopropyl- 1,4-dimethylazulene
Guajazulen
Guaiazulene, 99%
Azulene,4-dimethyl-
Guaiazulene (Standard)
Spectrum_001198
Spectrum2_001089
Spectrum3_001537
Spectrum4_000762
Spectrum5_001090
GUAIAZULENE [INCI]
BSPBio_002954
KBioGR_001144
KBioSS_001678
MLS002207286
DivK1c_001006
SPECTRUM1502249
SPBio_001138
AZ-8
1,4-Dimethyl-7-isopropylazulen
CHEMBL1408759
HMS503I13
HY-N6951R
KBio1_001006
KBio2_001678
KBio2_004246
KBio2_006814
KBio3_002454
Azulene,4-dimethyl-7-isopropyl-
NSC4714
NINDS_001006
HY-N6951
Tox21_111526
BBL027440
CCG-40099
s3995
STK801958
AKOS001082716
Tox21_111526_1
DB13329
FG34015
LMPR0103410006
SDCCGMLS-0066686.P001
WLN: L57J B1 F1 IY1&1
IDI1_001006
Azulene,4-dimethyl-7-(1-methylethyl)-
NCGC00095836-01
NCGC00095836-03
NCGC00095836-05
NCGC00178373-01
AS-13972
SMR001306801
DB-051592
1,4-Dimethyl-7-isopropylazulene;Guaiazulene
Azulene, 7-isopropyl-1,4-dimethyl- (8CI)
CS-0021588
G0228
NS00008692
7-isopropyl-1,4-dimethyl-azulene;Guaiazulene
EN300-16623
GUAIAZULENE (CONSTITUENT OF CHAMOMILE)
A10803
C09675
D01037
A827639
SR-05000002441
Q3026266
SR-05000002441-1
BRD-K36719159-001-04-9
Z56347227