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Coumarin 334

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Identification
Molecular formula
C15H17NO2
CAS number
126851-23-6
IUPAC name
7-(diethylamino)-4-methyl-chromen-2-one
State
State

It is a solid at room temperature. Coumarin 334 is usually handled in powdered form for research and experimental purposes.

Melting point (Celsius)
88.00
Melting point (Kelvin)
361.15
Boiling point (Celsius)
289.00
Boiling point (Kelvin)
562.15
General information
Molecular weight
261.32g/mol
Molar mass
261.3230g/mol
Density
1.1450g/cm3
Appearence

Coumarin 334 appears as a yellow crystalline solid. It has a characteristic aromatic odor that is quite pleasant and sweet. The structure comprises a chromone framework that gives it a distinct fluorescent appearance, especially under UV light due to its chromophore groups.

Comment on solubility

Solubility of 7-(diethylamino)-4-methyl-chromen-2-one

The solubility of 7-(diethylamino)-4-methyl-chromen-2-one is an interesting topic for discussion, particularly due to its unique chemical structure. This compound is typically characterized by its chromone backbone, which can greatly influence its interactions with solvents.

In terms of solvent compatibility, it tends to exhibit the following solubility behavior:

  • Organic Solvents: 7-(diethylamino)-4-methyl-chromen-2-one is generally soluble in a range of organic solvents such as ethanol, methanol, and chloroform. This is likely due to its hydrophobic properties and the ability of the organic solvents to disrupt intermolecular interactions.
  • Aqueous Solubility: In contrast, the compound's aqueous solubility tends to be quite limited. The presence of the diethylamino group enhances solvation to a degree, but the overall structure still leans towards hydrophobicity, leading to poor solubility in water.
  • pH Influence: It is noteworthy that the solubility could vary with pH, particularly due to the presence of the amino group, which may be protonated under acidic conditions, potentially affecting its solubility profile.

As a summary, while this compound shows appreciable solubility in organic environments, it is less soluble in water, which underscores the importance of considering solvent selection based on the application context. As is often said in the world of chemistry, "Like dissolves like," highlighting the significance of polarity in predicting solubility.

Interesting facts

Interesting Facts about 7-(Diethylamino)-4-methyl-chromen-2-one

7-(Diethylamino)-4-methyl-chromen-2-one is a fascinating compound that belongs to the class of flavonoids, a group renowned for their diverse biological activities. This compound's structure showcases the chromen-2-one framework, which is pivotal in the chemistry of natural products.

Key Features and Applications:

  • Biological Activity: Compounds with similar structures to 7-(diethylamino)-4-methyl-chromen-2-one have demonstrated various pharmacological effects, including antioxidant, anti-inflammatory, and anticancer properties.
  • Fluorescent Properties: This compound exhibits unique fluorescent characteristics, making it useful in applications such as fluorescent labeling and sensors in biochemical assays.
  • Research Interest: Given its structure, scientists are exploring its potential in the field of medicinal chemistry, particularly in drug design. The diethylamino moiety is thought to enhance solubility and biological activity.

These features underscore the importance of 7-(diethylamino)-4-methyl-chromen-2-one in both synthetic and natural product chemistry. Researchers are continually excited about the broad spectrum of biological applications and the potential discoveries that await within this intriguing compound.

As one researcher puts it, "The challenge and excitement of exploring chromens lie in their versatility and potential; each compound reveals a new frontier in medicinal research."

Overall, 7-(diethylamino)-4-methyl-chromen-2-one stands as an example of the rich tapestry of chemical compounds that offer promise in the realm of scientific discovery!

Synonyms
7-DIETHYLAMINO-4-METHYLCOUMARIN
91-44-1
Coumarin 1
7-(Diethylamino)-4-methyl-2H-chromen-2-one
Coumarin 460
Coumarin 47
7-(Diethylamino)-4-methylcoumarin
4-Methyl-7-(diethylamino)coumarin
Diethylaminomethylcoumarin
2H-1-Benzopyran-2-one, 7-(diethylamino)-4-methyl-
Blancophor AW
Blancophor FFG
Fluorescent brightener 52
Hakkol P
Uvitex WGS
4-Methyl-7-diethylaminocoumarin
Calcofluor White RW
Calcofluor White SD
Coumarin, 7-(diethylamino)-4-methyl-
Aclarat 8678
MDAC
7D4MC
12224-03-2
7-(diethylamino)-4-methylchromen-2-one
MDAC)
7-(Diethylamino)-4-methyl-2H-1-benzopyran-2-one
Hiltamine Artic White SOL
NSC 61830
CCRIS 5907
HSDB 4244
coumarin-1
C.I. Fluorescent Brightener 140
FLUORESCENT BRIGHTENER 140
61968-71-6
Coumarin, 7-diethylamino-4-methyl-
EINECS 202-068-9
1SFJ7F6R2C
MFCD00006864
BRN 0193303
7-(Diethylamino)-4-methyl-2-benzopyrone
C 47
DTXSID9025035
CHEBI:51938
AI3-18869
C.I. Fluorescent Brightener 52
NSC-61830
CHEMBL315348
DTXCID405035
C.I. 551100
NSC61830
7'-(Diethylamino)-4-methylcoumarin
Uvitex swn
7-DIETHYLAMINO-4-METHYLCOUMARIN [HSDB]
7-Diethylamino-4-methylcoumarin (purified by sublimation)
CAS-91-44-1
7-diethylamino-4-methyl coumarin
UNII-1SFJ7F6R2C
6ZW
7-(diethylamino)-4-methyl-chromen-2-one
ChemDiv3_000065
7Diethylamino4methylcoumarin
Oprea1_704968
SCHEMBL67108
MLS002152891
BIDD:GT0821
4Methyl7(diethylamino)coumarin
7(Diethylamino)4methylcoumarin
Coumarin, 7(diethylamino)4methyl
HMS1473C21
HMS3039I13
BCP27312
HY-D0082
C 47 (COUMARIN DERIVATIVE)
Tox21_201789
Tox21_303285
AC2163
BBL027619
BDBM50078833
CCG-15101
STK874253
AKOS001483296
WLN: T66 BOVJ E1 IN2&2
2434_7-Diethylamino-4-methylcoumarin
7-Diethylamino-4-methylcoumarin, 99%
FD54872
DIETHYLAMINOMETHYLCOUMARIN [INCI]
IDI1_019383
7(Diethylamino)4methyl2H1benzopyran2one
NCGC00091624-01
NCGC00091624-02
NCGC00091624-03
NCGC00172593-01
NCGC00257038-01
NCGC00259338-01
AC-16889
AS-14613
SMR001224503
SY012944
2H1Benzopyran2one, 7(diethylamino)4methyl
DB-000603
CS-0009995
D5730
M0631
NS00009481
7-(Diethylamino)-4-methyl-2H-chromen-2-one #
AF-960/00437064
EN300-18465514
SR-01000389311
SR-01000389311-1
BRD-K26694113-001-01-7
Q27123009
7-Diethylamino-4-methyl-chromen-2-one;7-Diethylamino-4-methyl-1-benzo-pyran-2-one
612-902-7