Interesting facts
Interesting Facts about 7-Chloro-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepine
The compound 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepine is a fascinating member of the benzodiazepine family, widely known for its distinct structural characteristics and potential pharmacological applications. Here are some intriguing aspects of this compound:
- Benzodiazepine Backbone: The unique structure of benzodiazepines allows them to interact with the central nervous system, primarily functioning as anxiolytics, hypnotics, and muscle relaxants.
- Chlorine Atom: The presence of the chlorine atom at the 7 position enhances the compound's efficacy and potency, making it more effective in neuropharmacological contexts.
- Research Interest: This compound has garnered attention in scientific research for its potential therapeutic benefits, particularly in treating anxiety and stress-related disorders.
- Synthetic Pathways: The synthesis of this compound involves intricate reactions, showcasing the creativity and complexity within organic chemistry and medicinal chemistry.
- Bioactivity: Preliminary studies suggest that the 1-methyl and 5-phenyl groups contribute to the compound's bioactivity, affecting interaction with GABA receptors.
As researchers continue to explore the multifaceted properties of benzodiazepines, compounds like 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepine are crucial in understanding the development of effective therapeutic agents. This underscores the importance of chemical research and the quest for new medication solutions in modern medicine.
Synonyms
medazepam
Rudotel
Nobrium
Resmit
Nivelton
Ansilan
Enobrin
Narsis
2898-12-6
Aensius
Azepamide
Lerisum
Medaurin
Navizil
Nobraksin
Pamnace
Stratium
Benaon
Nobral
Medazepamum
1H-1,4-BENZODIAZEPINE, 7-CHLORO-2,3-DIHYDRO-1-METHYL-5-PHENYL-
Medazepamum [INN-Latin]
Medazepam [INN:BAN:JAN]
Pamnace (TN)
DTXSID1048708
P0J3387W3S
MEDAZEPAM [INN]
MEDAZEPAM [JAN]
MEDAZEPAM [MI]
EINECS 220-783-4
RB 252
7-Chloro-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepine
MEDAZEPAM [MART.]
MEDAZEPAM [WHO-DD]
BRN 0407983
CHEMBL28333
DTXCID8028634
2,3-Dihydro-7-chloro-1-methyl-5-phenyl-1H-1,4-benzodiazepine
7-Chloro-2,3-dihydro-1-methyl-5-phenyl-3H-1,4-benzodiazepine
1H-1,4-Benzodiazepine, 2,3-dihydro-7-chloro-1-methyl-5-phenyl-
Ansius
Elbrus
Nobrium HCl
NCGC00164523-01
7-chloro-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepine
7-Chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepine
Medazepamum (INN-Latin)
Nobrium hydrochloride
MEDAZEPAM (MART.)
5-23-09-00037 (Beilstein Handbook Reference)
Mezapam
1H-1,4-Benzodiazepine, 7-chloro-2,3-dihydro-1-methyl-5-phenyl-, monohydrochloride
NSC169896
RB-252
Psiquium
DEA No. 2836
Diepin (Salt/Mix)
Elbrus (Salt/Mix)
Esmail (Salt/Mix)
Medazepol (Salt/Mix)
Megasedan (Salt/Mix)
Medazepam (JP17/INN)
SCHEMBL18472
UNII-P0J3387W3S
CHEBI:31807
N05BA03
Medazepam, 1mg/ml in Acetonitrile
Tox21_113107
BDBM50021058
STL257370
AKOS002254761
DB13437
CAS-2898-12-6
DB-047498
NS00010390
D01292
Q572796
1-methyl-5-phenyl-7-chloro-2,3-dihydro-1H-1,4-benzodiazepine
7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-[1,4]benzodiazepine
7-Chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepine #
7-Chloro-1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepine
(Z)-7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepine
1H-1,4-Benzodiazepine, 7-chloro-2, 3-dihydro-1-methyl-5-phenyl, monohydrochloride
7-Chloro-2, 3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepine, hydrochloride
7-Chloro-2,3-dihydro-1-methyl-5-phenyl-1H-1, 4-benzodiazepine monohydrochloride
220-783-4
Solubility of 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepine
The solubility of the compound 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepine (C16H13ClN2) is an important aspect to consider in its applications and behavior in various environments. The solubility can greatly influence its pharmacokinetics and bioavailability.
Key Factors Affecting Solubility:
In general, benzodiazepines tend to exhibit low water solubility but can demonstrate higher solubility in organic solvents. This is particularly relevant for pharmaceutical formulations. Various studies indicate that the solubility of similar compounds is influenced by:
Ultimately, understanding the solubility of 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepine is crucial for its development and efficacy in therapeutic applications.