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Methylene Blue

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Identification
Molecular formula
C16H18N3SCl
CAS number
61-73-4
IUPAC name
(7-amino-8-methyl-phenothiazin-3-ylidene)-dimethyl-ammonium
State
State

At room temperature, Methylene Blue is typically in a solid state, appearing as a dark green crystal or powder.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
319.85g/mol
Molar mass
319.8510g/mol
Density
0.6101g/cm3
Appearence

Methylene blue appears as a dark green crystalline powder. When dissolved in water, it produces a deep blue solution, which is characteristic of the compound. The intensity of the blue color depends on the concentration of the solution.

Comment on solubility

Solubility of (7-amino-8-methyl-phenothiazin-3-ylidene)-dimethyl-ammonium

The solubility behavior of (7-amino-8-methyl-phenothiazin-3-ylidene)-dimethyl-ammonium can be intriguing due to its unique structure. Understanding the solubility of this compound is essential, particularly for applications in pharmaceuticals and dye chemistry. Here are some key points to consider:

  • Polar vs. Nonpolar: The presence of the ammonium group in the structure suggests that this compound may be more soluble in polar solvents, such as water, due to its ionizable nature.
  • Structural Influences: The phenothiazine core can influence solubility. While phenothiazines are often soluble in various organic solvents, modifications can either enhance or reduce this solubility.
  • pH Sensitivity: The solubility may also vary with pH levels, especially considering the presence of the amino group. Changes in the pH can lead to protonation or deprotonation, affecting solubility.
  • Temperature Dependence: As with many compounds, solubility can increase with temperature—hence, warmer conditions might result in higher solubility for practical applications.

In summary, the solubility of (7-amino-8-methyl-phenothiazin-3-ylidene)-dimethyl-ammonium is likely to be influenced by its ionic character, polarity, and environmental conditions. This compound’s behavior highlights the importance of understanding solubility in the context of its chemical structure and potential applications.

Interesting facts

Interesting Facts about (7-amino-8-methyl-phenothiazin-3-ylidene)-dimethyl-ammonium

(7-amino-8-methyl-phenothiazin-3-ylidene)-dimethyl-ammonium is a fascinating compound with a rich history and significant applications in various fields. Its structure features a phenothiazine backbone, which is well-known for its diverse biological activities and is often explored in medicinal chemistry.

Key Features:

  • Biological Activity: Compounds derived from phenothiazines are commonly used in the development of pharmaceuticals, particularly as antipsychotic agents.
  • Versatility: The amine and methyl substituents enhance the compound's reactivity and solubility, making it applicable in drug formulation and delivery systems.
  • Research Potential: Ongoing research into this compound's mechanism of action continues to reveal novel therapeutic properties, including anti-inflammatory and antimicrobial effects.

Notably, many scientists have referred to phenothiazine derivatives as "the drugs that changed psychiatry." This highlights the tremendous impact these compounds have had on mental health treatments.

Applications in Science:

  • Medicine: These compounds are vital in the synthesis of various treatments aimed at psychological disorders.
  • Dyes and Indicators: Their vibrant color properties make them useful in the development of dyes and pH indicators.
  • Research Tools: Used in biological staining techniques to identify cellular structures.

The exploration of (7-amino-8-methyl-phenothiazin-3-ylidene)-dimethyl-ammonium and its derivatives continues to be a promising area of study in chemistry, captivating researchers with their complexity and plethora of applications. As we delve deeper into the chemical universe, compounds like this remind us of the potential that lies within seemingly simple molecular structures.

Synonyms
Tolonium
Tolonium cation
Tolonium ion
56109-24-1
UNII-P3Y6XJA2D1
P3Y6XJA2D1
Phenothiazin-5-ium, 3-amino-7-(dimethylamino)-2-methyl-
CHEBI:87648
TOLONIUM [WHO-DD]
3-Amino-7-(dimethylamino)-2-methylphenothiazin-5-ium
MLS000738130
NSC11225
NCGC00181775-01
SMR000393892
SCHEMBL460238
SCHEMBL2626791
(7-amino-8-methylphenothiazin-3-ylidene)-dimethylazanium
CHEMBL1622638
BDBM52827
DTXSID50859161
cid_16682403
BDBM50430742
NCI60_000268
NS00004526
NS00040892
AB00443638_08
N7,N7,2-trimethylphenothiazin-5-ium-3,7-diamine
BRD-K94882685-003-09-2
Q27159802
(7-amino-8-methyl-3-phenothiazinylidene)-dimethylammonium;hydrochloride
(7-amino-8-methyl-phenothiazin-3-ylidene)-dimethyl-ammonium;hydrochloride
(7-amino-8-methylphenothiazin-3-ylidene)-dimethylazanium;hydrochloride
(7-azanyl-8-methyl-phenothiazin-3-ylidene)-dimethyl-azanium;hydrochloride