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Cefotaxime

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Identification
Molecular formula
C16H17N5O7S2
CAS number
63527-52-6
IUPAC name
7-[[4-(2-amino-1-carboxy-2-oxo-ethylidene)-1,3-dithietane-2-carbonyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State
Cefotaxime is typically encountered as a solid in its powder form at room temperature.
Melting point (Celsius)
163.00
Melting point (Kelvin)
436.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
455.45g/mol
Molar mass
455.4500g/mol
Density
1.3801g/cm3
Appearence

Cefotaxime, often recognized in its sodium salt form, typically appears as a white or almost white, crystalline powder. It is odorless or has a faint odor and is soluble in water, moderately soluble in methanol, and practically insoluble in acetone and ether.

Comment on solubility

Solubility of 7-[[4-(2-amino-1-carboxy-2-oxo-ethylidene)-1,3-dithietane-2-carbonyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

The solubility of the compound with the chemical formula C16H17N5O7S2 can be quite complex due to its intricate structure. Several factors influence its solubility:

  • Polarity: The presence of various functional groups, such as the carboxylic acid and amino groups, likely increases the compound's polarity, which can enhance its solubility in polar solvents, particularly water.
  • Hydrogen Bonding: The amino and carboxylic acid groups can participate in hydrogen bonding, which may further promote solubility in aqueous environments.
  • Solvent Interaction: The compound's solubility may also vary significantly depending on the solvent used. For example, organic solvents might achieve different solubility levels compared to water due to variations in intermolecular interactions.

In general, one could expect that this compound may have moderate solubility in water, but it would be essential to conduct empirical tests to confirm its solubility behavior under various conditions. As noted, "solubility is not just about the chemical's structure, but also about the surroundings it finds itself in." Understanding these dynamics can be crucial for practical applications in pharmaceuticals and materials science.

Interesting facts

Exploring 7-[[4-(2-amino-1-carboxy-2-oxo-ethylidene)-1,3-dithietane-2-carbonyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This remarkable compound showcases a rich tapestry of chemistry, with its complex structure and unique functional groups contributing to its significance in various fields. Here are some fascinating insights:

  • Bioactive Potential: Compounds like this one often exhibit promising pharmacological activities, including antimicrobial and anti-inflammatory properties, making them valuable in drug discovery.
  • Structural Diversity: The blend of dithietane and tetrazole moieties not only enhances the compound’s stability but also opens the door to a wide array of derivatives that can be synthesized.
  • Therapeutic Applications: Its structural resemblance to various natural products suggests potential applications in treating bacterial infections or possibly acting as an enzyme inhibitor.
  • Challenging Synthesis: The synthesis of such compounds can be a daunting task, often requiring sophisticated techniques and reaction conditions, thus presenting an intriguing challenge for organic chemists.
  • Interdisciplinary Appeal: This compound is of interest not only in organic chemistry but also in materials science and medicinal chemistry, illustrating the interconnectedness of scientific disciplines.

As noted by many chemists, "The beauty of chemistry lies in its diversity and the endless possibilities for discovery." This compound is a testament to that philosophy, encouraging rigorous exploration and innovative research.

In summary, 7-[[4-(2-amino-1-carboxy-2-oxo-ethylidene)-1,3-dithietane-2-carbonyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid serves as an exciting example of the intricate relationships within chemical compounds and their potential for real-world applications.