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Prostaglandin E2

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Identification
Molecular formula
C20H32O5
CAS number
363-24-6
IUPAC name
7-[3,5-dihydroxy-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid
State
State

At room temperature, prostaglandin E2 is in the liquid state.

Melting point (Celsius)
-6.00
Melting point (Kelvin)
267.15
Boiling point (Celsius)
263.00
Boiling point (Kelvin)
536.15
General information
Molecular weight
352.47g/mol
Molar mass
352.4660g/mol
Density
1.0588g/cm3
Appearence

Prostaglandin E2 is typically a colorless, viscous liquid. It is sensitive to light, oxygen, and temperature changes.

Comment on solubility

Solubility of 7-[3,5-dihydroxy-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid (C20H32O5)

The solubility of 7-[3,5-dihydroxy-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid, a complex organic compound, can be influenced by several factors, including its molecular structure and functional groups. The presence of hydroxyl (-OH) groups generally enhances solubility in polar solvents due to hydrogen bonding. However, the long hydrocarbon chain can create hydrophobic interactions, making the compound less soluble in water. Here are some considerations regarding its solubility:

  • Polar Solvents: It is likely to be more soluble in polar solvents, such as methanol and ethanol, due to the ability of the hydroxyl groups to form hydrogen bonds.
  • Non-polar Solvents: Conversely, the compound may exhibit greater solubility in non-polar solvents like hexane, driven by the hydrophobic nature of its alkyl chains.
  • Temperature Influence: Increased temperature usually enhances solubility; thus, heating the solvent may aid in dissolving the compound more effectively.
  • pH Effect: Changes in pH may affect its ionization state, potentially altering its solubility profile, particularly if the carboxylic acid group becomes ionized.

In summary, the solubility of this compound exhibits a dual nature characteristic of amphiphilic molecules, where both the hydrophilic and hydrophobic portions play critical roles in its behavior in various solvents. Understanding these solubility dynamics is essential for applications in chemical synthesis and biological systems.

Interesting facts

Interesting Facts about 7-[3,5-dihydroxy-2-(3-oxooctyl)cyclopentyl]hept-5-enoic Acid

This intriguing compound is a member of a diverse class of organic molecules that exhibit both structural complexity and versatile functionality. Here are some interesting aspects of this compound:

  • Biological Relevance: Compounds similar to this acid often play critical roles in biological systems, including functions in cellular signaling and metabolism. Studying them can provide insights into various physiological processes.
  • Structural Features: The presence of multiple hydroxyl groups in the structure indicates potential for hydrogen bonding, which can influence the compound's interactions with other biomolecules, potentially affecting its activity and stability.
  • Cyclopentyl Group: The cyclopentyl moiety introduces unique steric properties which can impact how the molecule behaves in a biological context, such as its ability to fit into enzyme active sites or interact with receptors.
  • Application in Research: This compound could serve as a valuable model in the study of fatty acids and lipids, especially in relation to their roles in inflammation and signaling pathways.
  • Potential Derivatives: The structure suggests that it could be modified into various derivatives, which may possess enhanced biological activity or improved pharmacological properties.

Overall, 7-[3,5-dihydroxy-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid is a prime example of the intricate connections between structure and function in organic chemistry. Its study could pave the way for novel therapeutic agents.

Synonyms
13,14-Dihydro-15-keto PGF2a
PD024595
DB-047213