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Prostaglandin E2

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Identification
Molecular formula
C20H32O5
CAS number
363-24-6
IUPAC name
7-[3,5-dihydroxy-2-(3-oxooct-1-enyl)cyclopentyl]hept-5-enoic acid
State
State

At room temperature, prostaglandin E2 is a liquid. It is lipid-soluble and is often found in biological systems dissolved in cellular membranes or in an aqueous environment when administered as a drug.

Melting point (Celsius)
-6.00
Melting point (Kelvin)
267.00
Boiling point (Celsius)
470.10
Boiling point (Kelvin)
743.20
General information
Molecular weight
352.47g/mol
Molar mass
352.4660g/mol
Density
1.0400g/cm3
Appearence

Prostaglandin E2 typically appears as a clear, colorless or pale yellow oil. It is often handled in solution form due to its high reactivity and biological activity.

Comment on solubility

Solubility of 7-[3,5-dihydroxy-2-(3-oxooct-1-enyl)cyclopentyl]hept-5-enoic acid (C20H32O5)

The solubility of 7-[3,5-dihydroxy-2-(3-oxooct-1-enyl)cyclopentyl]hept-5-enoic acid can provide insights into its chemical behavior and potential applications. Considering its complex structure, the solubility can be influenced by several factors:

  • Polarity: The presence of multiple hydroxyl (–OH) groups significantly increases polarity, which may enhance solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to these –OH groups can lead to greater interactions with solvent molecules, further increasing solubility.
  • Hydrophobic Interactions: The long hydrophobic tail (the octenyl group) might reduce solubility in polar solvents, yet it could increase solubility in non-polar organic solvents.
  • Concentration Effects: Increased concentration of the compound in solution might lead to varied solubility behaviors, which are essential for understanding its practical uses.

Moreover, it’s important to consider the solvent's temperature, pH, and presence of co-solvents in solubility assessments. General guidelines for solubility can state:

  1. “Like dissolves like.” Polar solvents dissolve polar compounds, while non-polar solvents are suitable for non-polar compounds.
  2. Temperature Variation: Solubility may increase with temperature, affecting how the compound interacts in various environments.

In preparation for practical applications, it’s beneficial to conduct specific solubility tests under controlled conditions to determine the exact solubility metrics for this compound.

Interesting facts

Interesting Facts about 7-[3,5-dihydroxy-2-(3-oxooct-1-enyl)cyclopentyl]hept-5-enoic acid

This intriguing compound is a type of fatty acid that displays fascinating biological properties and molecular complexity. Here are some notable aspects:

  • Structural Complexity: With its unique cyclopentyl structure and multiple hydroxyl groups, this compound showcases the diversity of natural and synthetic organic compounds.
  • Biological Significance: Compounds like this one can potentially play roles in *cell signaling* and may have implications in *bioactive lipid research*, making them important in fields such as *nutrition* and *pharmacology*.
  • Derivative Potential: The presence of both a carboxylic acid and a ketone group implies that this compound can serve as a precursor for the synthesis of more complex molecules, offering opportunities for chemical innovation.

As a scientist or chemistry student, exploring the various reactions that this compound can undergo, particularly in the realm of esterification and amidation, can lead to a deeper understanding of organic synthesis. The potential applications in medicinal chemistry, including the development of new drugs, add an exciting layer to its study.

In summary, 7-[3,5-dihydroxy-2-(3-oxooct-1-enyl)cyclopentyl]hept-5-enoic acid represents more than just a compound; it embodies the intricate relationship between structure and function in biochemistry. As we continue to decode the complex roles of such compounds in biological systems, we unlock the potential for groundbreaking discoveries in health and medicine.

Synonyms
8-iso-15-keto Prostaglandin F2 alpha
DTXSID20865794
PD049548
DB-048880
NS00016935