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Prostaglandin E2

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Identification
Molecular formula
C20H32O5
CAS number
363-24-6
IUPAC name
7-[3,5-dihydroxy-2-(3-hydroxyoct-1-enyl)cyclopentyl]hept-5-enoic acid
State
State

At room temperature, Prostaglandin E2 is typically a liquid. It is sensitive to light and heat, and thus is often handled under controlled conditions to prevent degradation.

Melting point (Celsius)
-6.00
Melting point (Kelvin)
267.20
Boiling point (Celsius)
374.70
Boiling point (Kelvin)
647.90
General information
Molecular weight
352.47g/mol
Molar mass
352.4660g/mol
Density
1.0101g/cm3
Appearence

Prostaglandin E2 is a viscous liquid that is colorless to pale yellow in appearance. It is commonly stored in solution form at low temperatures to maintain its stability, as it is temperature sensitive.

Comment on solubility

Solubility of 7-[3,5-dihydroxy-2-(3-hydroxyoct-1-enyl)cyclopentyl]hept-5-enoic acid

The solubility of 7-[3,5-dihydroxy-2-(3-hydroxyoct-1-enyl)cyclopentyl]hept-5-enoic acid (C20H32O5) is influenced by several factors related to its molecular structure and functional groups. Understanding its solubility characteristics can help anticipate its behavior in different environments. Here are some important points to consider:

  • Hydrophilic and Hydrophobic Interaction: The molecule contains multiple hydroxyl (-OH) groups, which confer some degree of hydrophilicity. This suggests that it may have some solubility in polar solvents such as water.
  • Non-Polar Regions: The presence of long hydrocarbon chains introduces non-polar characteristics, potentially enhancing solubility in organic solvents like ethanol or chloroform, while compromising solubility in water.
  • Temperature Dependency: Solubility can be significantly affected by temperature; generally, increased temperatures may improve solubility in both polar and non-polar solvents.
  • pH Dependence: The carboxylic acid group may also influence solubility depending on the pH of the solution, as ionization can enhance solubility in aqueous environments.

In summary, while it is likely that C20H32O5 has moderate solubility in water due to its hydroxyl groups, the combination of its amphiphilic nature indicates that it will have better solubility in organic solvents. Thus, it is essential to consider the solvent environment when assessing the compound's solubility.

Interesting facts

Interesting Facts about 7-[3,5-Dihydroxy-2-(3-hydroxyoct-1-enyl)cyclopentyl]hept-5-enoic Acid

This compound is a fascinating example of a complex organic molecule with significant biochemical relevance. Its intricate structure not only showcases the beauty of natural product chemistry but also offers insights into various biological processes. Here are some noteworthy points about this compound:

  • Biological Significance: Compounds like this one are often bioactive, meaning they can interact with biological systems and potentially influence health-related mechanisms.
  • Structural Complexity: The presence of multiple hydroxyl (−OH) groups introduces *polarity* and *reactivity*, allowing for diverse chemical reactions and interactions.
  • Potential Applications: It may serve as a lead compound in drug development, especially in addressing conditions related to oxidative stress and inflammation.
  • Synthetic Routes: Chemists continue to explore efficient synthetic pathways for creating such compounds, as they often involve intricate steps that can challenge even seasoned synthetic chemists.
  • Natural Occurrence: This compound may be derived from natural sources, making it desirable for those interested in green chemistry approaches that utilize sustainable methods.

In the words of renowned chemist Linus Pauling, “The best way to have a good idea is to have lots of ideas.” Exploring such complex compounds encourages innovation and deep thinking in the field of chemistry. As research evolves, who knows what other applications this compound could unlock?

Synonyms
Prostaglandin F2a;PGF2alpha
146388-90-1
7-[3,5-dihydroxy-2-(3-hydroxyoct-1-enyl)cyclopentyl]hept-5-enoic acid
8-EPI-PROSTAGLANDIN F2a
MLS003107056
583E
SMR001821937
2-amino-2-(hydroxymethyl)propane-1,3-diol;7-[3,5-dihydroxy-2-(3-hydroxyoct-1-enyl)cyclopentyl]hept-5-enoic acid
11?-Prostaglandin f2?-d4
7-[3,5-Dihydroxy-2-(3-hydroxy-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid
CHEMBL2220614
BDBM97180
cid_44134913
PXGPLTODNUVGFL-UHFFFAOYSA-N
38432-87-0
QZB39818
9beta, 11alpha-PROSTAGLANDIN F2
DB-048923
NS00096440
7-[3,5-dihydroxy-2-(3-hydroxyoct-1-en-1-yl)cyclopentyl]hept-5-enoic acid
Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,8xi,12xi,13E)-
2-amino-2-(hydroxymethyl)propane-1,3-diol;7-[3,5-dihydroxy-2-(3-hydroxyoct-1-enyl)cyclopentyl]-5-heptenoic acid
2-amino-2-methylol-propane-1,3-diol;7-[3,5-dihydroxy-2-(3-hydroxyoct-1-enyl)cyclopentyl]hept-5-enoic acid
2-azanyl-2-(hydroxymethyl)propane-1,3-diol;7-[3,5-bis(oxidanyl)-2-(3-oxidanyloct-1-enyl)cyclopentyl]hept-5-enoic acid