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Amoxicillin

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Identification
Molecular formula
C16H19N3O5S
CAS number
26787-78-0
IUPAC name
7-[[2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-methyl-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State

Amoxicillin is generally available as a solid in various forms including tablets, capsules, and powder for suspension. At room temperature, it remains stable as a powder.

Melting point (Celsius)
194.00
Melting point (Kelvin)
467.15
Boiling point (Celsius)
212.00
Boiling point (Kelvin)
485.15
General information
Molecular weight
365.40g/mol
Molar mass
365.4040g/mol
Density
1.3600g/cm3
Appearence

Amoxicillin is a white, crystalline powder that is highly soluble in water. It may appear as a crystalline solid or powder and is known to be odorless.

Comment on solubility

Solubility of 7-[[2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-methyl-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

The solubility of this complex compound, C16H19N3O5S, can be influenced by various factors such as its structural characteristics and the presence of functional groups. Compounds of this nature typically exhibit varying degrees of solubility in different solvents.

Key Factors Affecting Solubility:

  • Polarity: The presence of multiple polar functional groups, such as carboxylic acids and hydroxyl groups, often enhances solubility in polar solvents like water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvent molecules can play a crucial role in the solubility of this compound.
  • Temperature: Increased temperature generally increases solubility, allowing for better dissolution of the compound in solvents.

As a result, it is likely that the compound demonstrates good solubility characteristics in aqueous solutions due to its hydrophilic components. Researchers often emphasize the importance of assessing solubility for practical applications in pharmaceutical and chemical industries, stating that "solubility is a key determinant of bioavailability and efficacy".

In conclusion, while the specific solubility of 7-[[2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-methyl-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid in different solvents would ideally be empirically determined, its complex structure suggests a favorable solubility profile in polar environments.

Interesting facts

Interesting Facts about 7-[[2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-methyl-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This compound, known for its complex structure, is fascinating not only for its intricate chemical makeup but also for its potential applications in the field of medicinal chemistry. Here are some compelling facts:

  • Biological Activity: The presence of the carboxylic acid and hydroxyphenyl groups may contribute to the compound's bioactivity, potentially offering therapeutic effects in treating various diseases.
  • Synthetic Routes: The synthesis of this compound could involve advanced organic synthesis techniques, showcasing the importance of functional group manipulation in creating complex molecules.
  • Research Significance: Researchers are particularly interested in compounds like this one for their role in the development of new pharmaceuticals, especially because they can lead to discoveries of novel drug candidates.
  • Structure-Activity Relationship (SAR): Understanding how structural variations in this compound affect its biological activity could provide insights into its mechanisms of action and ways to optimize its effectiveness.

As with many compounds in the realm of medicinal chemistry, the chance to explore their properties could lead to significant advancements in healthcare. Exploration of such compounds is critical in the continuous effort to tackle complex health challenges.


In conclusion, the study of 7-[[2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-methyl-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid not only reveals the intricacies of its structure but also opens doors to potential innovations in therapeutic applications.