Skip to main content

Cloxacillin

ADVERTISEMENT
Identification
Molecular formula
C19H17ClN3NaO5S
CAS number
61-72-3
IUPAC name
7-[(2-amino-2-cyclohexa-1,4-dien-1-yl-acetyl)amino]-3-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State

At room temperature, cloxacillin is typically in a solid state and often formulated for use in an injectable form, capsules, or as a suspension.

Melting point (Celsius)
172.00
Melting point (Kelvin)
445.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.00
General information
Molecular weight
435.91g/mol
Molar mass
435.9100g/mol
Density
1.5000g/cm3
Appearence

Cloxacillin typically appears as a white or almost white crystalline powder. It may be available as a powder intended for dissolution or as capsules for oral administration.

Comment on solubility

Solubility of 7-[(2-amino-2-cyclohexa-1,4-dien-1-yl-acetyl)amino]-3-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

The solubility characteristics of the compound with the chemical formula C19H17ClN3NaO5S are influenced by various factors, including its molecular structure and the presence of polar functional groups.

In general, the solubility of this compound can be summarized as follows:

  • Water Solubility: The presence of the sodium (Na) ion and carboxylic acid groups suggests that this compound could have enhanced solubility in polar solvents such as water.
  • Solubility in Organic Solvents: The methoxy group and thioether functionalities indicate potential solubility in organic solvents like ethanol and dimethylsulfoxide (DMSO), which are commonly used in pharmaceutical and chemical applications.
  • Effect of pH: Changes in pH can significantly affect the solubility due to the ionization of the carboxylic acid moiety, making it more soluble in alkaline conditions.

Overall, while exact solubility data may vary, the structural features of this compound point towards a favorable solubility profile in both polar and non-polar environments. Understanding these solubility properties is crucial for applications in drug formulation and delivery systems.

Interesting facts

Interesting Facts about 7-[(2-amino-2-cyclohexa-1,4-dien-1-yl-acetyl)amino]-3-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This intriguing compound, often referred to as a thiazole derivative, represents a fascinating intersection of organic chemistry and drug design. Here are some notable aspects:

  • Complex Structure: The compound features a bicyclic system, which is significant for its biological activity and potential medicinal properties. Such complexity often enhances interactions with biological targets.
  • Potential Therapeutic Uses: Compounds like this one have been explored for their antibacterial and antifungal properties, making them of interest in pharmaceutical research.
  • Thiazole Ring: The thiazole moiety in the structure can contribute to various biochemical interactions, providing unique advantages in drug development.
  • Amino Acid Derivative: The presence of an amino group opens pathways for further modifications, which can tailor the compound's effectiveness and bioavailability.

In the world of chemical synthesis, compounds like this exemplify the intricate balance of structure and function. As researchers continue to explore and modify similar compounds, the potential for novel drug candidates increases, demonstrating that even complex molecules can lead to targeted and effective treatments in modern medicine.

"The beauty of chemistry lies in its complexity; the more we understand, the more we can create." - A reminder that every intricate structure has the potential to yield significant breakthroughs.

Synonyms
DTXSID90860635
7-[2-Amino(cyclohexa-1,4-dien-1-yl)acetamido]-3-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid