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Cefonicid

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Identification
Molecular formula
C18H17N5O8S3
CAS number
61270-58-4
IUPAC name
7-[[2-[(5-carboxy-1H-imidazole-4-carbonyl)amino]-2-phenyl-acetyl]amino]-3-[[4-(2-sulfoethyl)pyridin-1-ium-1-yl]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State
Cefonicid is a solid at room temperature. It is typically available as its sodium salt form for intravenous or intramuscular injection.
Melting point (Celsius)
190.00
Melting point (Kelvin)
463.15
Boiling point (Celsius)
282.00
Boiling point (Kelvin)
555.15
General information
Molecular weight
585.63g/mol
Molar mass
585.6290g/mol
Density
1.4000g/cm3
Appearence

Cefonicid sodium appears as a white to yellowish crystalline powder. It is usually odorless or may have a slightly characteristic odor. It is soluble in water and very slightly soluble in methanol.

Comment on solubility

Solubility of 7-[[2-[(5-carboxy-1H-imidazole-4-carbonyl)amino]-2-phenyl-acetyl]amino]-3-[[4-(2-sulfoethyl)pyridin-1-ium-1-yl]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

The solubility of the compound, 7-[[2-[(5-carboxy-1H-imidazole-4-carbonyl)amino]-2-phenyl-acetyl]amino]-3-[[4-(2-sulfoethyl)pyridin-1-ium-1-yl]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, is influenced by various structural factors and functional groups present within its molecular framework.

  • Polarity: The presence of multiple carboxylic acid groups and a sulfonium moiety suggests high polarity, which generally enhances solubility in polar solvents such as water.
  • Hydrophilic Interactions: The compound's functional groups are likely to engage in hydrogen bonding, contributing to *increased solubility* in aqueous environments.
  • Salt Formation: The sulfonium group may lead to increased solubility through ionization in solvent systems, particularly if the pH is appropriately adjusted.

However, the overall solubility can be variable depending on factors such as the presence of other ions in solution, temperature, and the specific solvent used. It is often recommended to conduct solubility tests under controlled conditions to determine precise solubility characteristics.

In summary, while this compound exhibits properties that favor solubility in polar solvents, *experimental validation* is essential to comprehensively understand its behavior in solution. As molecular interactions are complex, different environmental conditions can significantly impact solubility outcomes.

Interesting facts

Interesting Facts About 7-[[2-[(5-carboxy-1H-imidazole-4-carbonyl)amino]-2-phenyl-acetyl]amino]-3-[[4-(2-sulfoethyl)pyridin-1-ium-1-yl]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This compound represents a fascinating intersection of biochemistry and pharmacology, due to its complex structure and potential applications. Here are some intriguing details:

  • Bioactive Potential: The compound is believed to play a role in the modulation of various biological pathways, making it a candidate for drug discovery and development.
  • Functional Groups: Its structure includes multiple functional groups such as carboxylic acids, amides, and sulfo groups, which can aid in the solubility and biological activity of the compound.
  • Unique Structure: The bicyclic framework presents a unique topology that could influence how the compound interacts with its biological targets.
  • Imidazole Moiety: The presence of the imidazole ring is significant since compounds with this structure often exhibit important properties, including antimicrobial and antifungal activities.
  • Pharmaceutical Relevance: This compound's structural features suggest that it may have applications in developing therapies for diseases caused by microbial infections or metabolic dysregulations.

As a chemistry student, you might find yourself pondering questions such as: How does the spatial arrangement of atoms affect the compound's interaction with enzymes or receptors? Moreover, studying such compounds can enhance your understanding of molecular design principles in medicinal chemistry.

Overall, this compound serves as a remarkable example of how complex molecular structures can lead to significant advancements in therapeutic sciences.