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Cefepime

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Identification
Molecular formula
C19H24N6O5S2
CAS number
88040-23-7
IUPAC name
7-[[2-(4-hydroxyphenyl)-2-[(6-methyl-4-oxo-1H-pyridine-3-carbonyl)amino]acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State

At room temperature, Cefepime is in a solid state, typically found as a powder used for pharmaceutical applications. It is often formulated into injectable forms for medical use.

Melting point (Celsius)
161.00
Melting point (Kelvin)
434.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
480.57g/mol
Molar mass
480.5730g/mol
Density
1.7900g/cm3
Appearence

Cefepime appears as a white to pale yellow powder. It is commonly available in a crystalline form, which is used in pharmaceutical preparations. The compound does not have a discernible odor and is relatively stable when kept dry.

Comment on solubility

Solubility of 7-[[2-(4-hydroxyphenyl)-2-[(6-methyl-4-oxo-1H-pyridine-3-carbonyl)amino]acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (C19H24N6O5S2)

The solubility of complex organic compounds like this one can often be challenging to determine due to their intricate structures. However, here are some noteworthy aspects regarding its solubility:

  • Polarity: Given the presence of multiple functional groups, including hydroxyl (–OH) and carboxylic acids (–COOH), this compound is expected to exhibit significant polarity. This suggests potential solubility in polar solvents such as water.
  • Hydrophilicity: The hydroxyl groups contribute to the compound's hydrophilicity, enhancing its ability to dissolve in aqueous solutions.
  • Non-polar characteristics: The presence of bulky non-polar groups may impede solubility in purely polar solvents, indicating a complex interaction of solubility behavior.
  • Solvent interactions: It is likely to show varied solubility in different organic solvents, possibly dissolving well in solvents like DMSO or ethanol due to their ability to stabilize polar functionalities.

In summary, while the solubility of this compound is influenced by its diverse structural components, the overall expectation leans toward moderate solubility in polar solvents, but with potential solubility in certain non-polar environments as well. Understanding these properties can aid in its application in various chemical and pharmaceutical processes.

Interesting facts

Interesting Facts about 7-[[2-(4-hydroxyphenyl)-2-[(6-methyl-4-oxo-1H-pyridine-3-carbonyl)amino]acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This compound is a fascinating example of modern medicinal chemistry, showcasing how complex structures can lead to potent biological activity. Here are some intriguing aspects of this compound:

  • Multi-functional Moiety: The presence of multiple functional groups, including a pyridine scaffold and a tetrazole ring, suggests that this compound may have diverse pharmacological properties. Such configurations are often associated with enhanced interactions with biomolecules.
  • Biochemical Significance: Compounds like this are often developed as potential drug candidates. Their unique structures can inhibit specific enzymes or receptors, which is vital in the treatment of various diseases.
  • Potential Therapeutic Applications: The combination of the thiazole and beta-lactam-like structures highlights its potential as an antibiotic or anti-cancer agent, making it a subject of interest for research in drug development.
  • Complex Synthesis: The synthesis of such a complex molecule poses significant challenges and requires advanced organic synthetic techniques and methodologies, showcasing the ingenuity of chemists.

Considering the intricate chemistry involved, one could say, "Every complex compound tells a story," pointing towards its potential biomedical applications and the exciting path of discovery for novel therapeutics. As research continues, we might uncover even more about the capabilities and functionalities of this remarkable compound.

Synonyms
Cefpiramide acid; Cefpiramide
DTXSID30860917
BCP21303
DB-055452
SR-01000943933
SR-01000943933-1
7-{2-[(4-Hydroxy-6-methylpyridine-3-carbonyl)amino](4-hydroxyphenyl)acetamido}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid