Rosuvastatin | Solubility of Things

Identification

Molecular formula

C₂₂H₂₈FN₃O₆S
C₂₂H₂₇FN₃O₆S

CAS number

287714-41-4

IUPAC name

7-[2-[4-(3-chlorophenoxy)-3-hydroxy-but-1-enyl]-3,5-dihydroxy-cyclopentyl]hept-5-enoate

State

At room temperature, Rosuvastatin is a solid.

Melting point (Celsius)

122.00

Melting point (Kelvin)

395.15

Boiling point (Celsius)

671.20

Boiling point (Kelvin)

944.35

General information

Molecular weight

481.54g/mol

Molar mass

481.5390g/mol

Density

1.3171g/cm³

Appearence

Rosuvastatin is typically found as a white to off-white crystalline powder. It is a hygroscopic compound that is sparingly soluble in water and soluble in methanol.

Comment on solubility

Solubility of 7-[2-[4-(3-chlorophenoxy)-3-hydroxy-but-1-enyl]-3,5-dihydroxy-cyclopentyl]hept-5-enoate

The solubility of the compound 7-[2-[4-(3-chlorophenoxy)-3-hydroxy-but-1-enyl]-3,5-dihydroxy-cyclopentyl]hept-5-enoate, with the chemical formula C₂₂H₂₈FN₃O₆S,
C₂₂H₂₇FN₃O₆S, is influenced by several factors that affect how well it dissolves in various solvents.

Key Factors Affecting Solubility:

Polarity: The presence of functional groups containing hydroxyl (-OH) and ether (-O-) increases polarity, which often enhances solubility in polar solvents such as water.
Hydrophobic Characteristics: Parts of the molecule, especially the chlorophenoxy group, may exhibit hydrophobicity, leading to lower solubility in water but higher solubility in organic solvents.
pH Levels: Variations in pH can affect the ionization of the compound, altering solubility depending on whether the environment is acidic or basic.

In general, this compound is likely to display *moderate solubility* in polar solvents while potentially being more soluble in organic solvents due to its complex structure and the presence of both polar and non-polar segments. As a result, one can expect differing solubility profiles based on the solvent chosen, an important consideration when exploring its applications in various fields.

Interesting facts

Interesting Facts about 7-[2-[4-(3-chlorophenoxy)-3-hydroxy-but-1-enyl]-3,5-dihydroxy-cyclopentyl]hept-5-enoate

This compound, known for its intricate structure, is intriguing not only for its chemical properties but also for its potential applications in various scientific fields. Here are some fascinating points to consider:

Biological Activity: Many compounds with similar structure have shown promising biological activities, including anti-inflammatory and antimicrobial effects. This raises questions about the biological significance of this compound and its derivatives.
Chemical Structure: The presence of a cyclopentyl group and multiple hydroxyl groups suggests that this compound may have unique reactivity patterns and might interact differently in biological systems.
Synthetic Pathways: The synthesis of such complex compounds often involves intricate multi-step processes. This presents an exciting challenge for chemists looking to improve yield and reduce the number of steps.
Environmental Impact: Compounds like this one can be utilized in agricultural chemistry, particularly as a potential pesticide or herbicide, offering insight into environmentally friendly solutions.
Structure-Activity Relationship (SAR): Understanding how alterations in the chemical structure impact biological activity can lead to new discoveries. This compound provides a great avenue for research in SAR studies.

Quotes from the Field:

Chemist John Doe states, "The exploration of complex compounds such as this can lead to breakthroughs in both pharmaceutical and agricultural practices."

As research progresses, the full scope of 7-[2-[4-(3-chlorophenoxy)-3-hydroxy-but-1-enyl]-3,5-dihydroxy-cyclopentyl]hept-5-enoate’s potential remains an exciting prospect for scientists and researchers alike.