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7-hydroxymitragynine

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Identification
Molecular formula
C23H30N2O4
CAS number
4429-13-6
IUPAC name
(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
State
State

At room temperature, 7-hydroxyindolin-2-one typically exists as a solid. It maintains its structural integrity well in average conditions but should be stored in a dry environment as it can be hygroscopic, absorbing moisture from the air, which may alter its consistency.

Melting point (Celsius)
102.00
Melting point (Kelvin)
375.15
Boiling point (Celsius)
530.70
Boiling point (Kelvin)
803.85
General information
Molecular weight
398.50g/mol
Molar mass
174.1710g/mol
Density
1.2950g/cm3
Appearence

7-Hydroxyindolin-2-one is typically a crystalline solid with a pale color. Its exact coloration can vary from white to a slight off-white, indicating purity levels. In its pure form, it is odorless and has a defined crystalline structure, often appearing as fine powders or larger crystalline chunks. When handled, it may have a slight stickiness due to its natural moisture-absorbing properties.

Comment on solubility

Solubility of (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol

The solubility of (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol, with a chemical formula of C23H30N2O4, can be characterized by several key factors:

  • Polarity: This compound contains hydroxyl (-OH) groups, which generally increase solubility in polar solvents, particularly water.
  • Hydrophobic Character: The presence of the multiple benzene rings contributes to a hydrophobic region, which can hinder solubility in aqueous environments.
  • Solvent Interaction: Solubility may vary significantly depending on the solvent used. For instance, it may exhibit higher solubility in organic solvents like ethanol and dimethyl sulfoxide (DMSO) compared to water.
  • Temperature: Like many organic compounds, solubility tends to increase with temperature, which may further influence its solubility profile.

In summary, while the hydroxyl groups provide potential for solubility in polar solvents, the hydrophobic characteristics due to the polycyclic structure suggest that its overall solubility may be limited in water. Understanding these solubility characteristics is essential for predicting behavior in various chemical environments.

Interesting facts

Interesting Facts about (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol

(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol is a fascinating compound within the realm of organic chemistry, notable for its unique structure and potential applications. Here are some engaging aspects of this compound:

  • Structural Complexity: This compound is characterized by a multi-ring structure that includes both aromatic and saturated elements, offering a rich landscape for exploration in medicinal chemistry.
  • Medicinal Potential: Compounds similar to this one have been studied for their therapeutic potential, including anti-inflammatory and anti-cancer properties. The intricate structure may contribute to its biological activity.
  • Natural Origin: Some dibenzoquinoline derivatives are isolated from natural sources, highlighting the interesting relationship between structure and biological function.
  • Synthetic Pathways: The synthesis of such compounds can involve complex organic reactions, showcasing the creativity and innovation required in modern chemistry.
  • Applications in Research: Due to its unique configuration, this compound may serve as a valuable building block in the synthesis of more complex chemical entities, and in studying the interactions of various biological systems.

As noted by chemists, "The beauty of chemistry lies in the molecular structures and the stories they can tell about their functions and interactions." The study of (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol serves as a reminder of the endless possibilities within the world of chemical compounds. It invites further exploration into its properties and potential implications in various fields, encouraging a deeper appreciation for the intricate dance of molecules in our universe.

Synonyms
apomorphine
58-00-4
L-Apomorphine
Apomorfin
Apomorphin
R-(-)-Apomorphine
Ixense
(R)-(-)-Apomorphine
Apokyn
Uprima
Apomorphinum
(-)-10,11-Dihydroxyaporphine
6abeta-Aporphine-10,11-diol
VR-040
Apomorphine hydrochloride
6a-beta-Aporphine-10,11-diol
HSDB 3289
UNII-N21FAR7B4S
EINECS 200-360-0
N21FAR7B4S
(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
Apomorphine [BAN]
Apomorphine free base
DTXSID8022614
CHEBI:48538
VR040
(6aR)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo(de,g)chinolin-10,11-diol
Apomorphine hydrochloride hemihydrate
CHEMBL53
Kynmobi (sublingual film)
APL-130277
Apormorphine
4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, (R)-
58-00-4 (free base)
DTXCID302614
6a.beta.-aporphine-10,11-diol
Apomorphine (BAN)
Apomorphinium chloride hemihydrate
NCGC00025349-02
Uprima (TN)
(-)-Apomorphine
(R)?-?(-?)?-?Apomorphine
(R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol
(6AR)-5,6,6A,7-TETRAHYDRO-6-METHYL-4H-DIBENZO(DE,G)QUINOLINE-10,11-DIOL
CAS-58-00-4
(9R)-10-methyl-10-azatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2,4,6,13,15-hexaene-3,4-diol
Apomorfina
(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo(de,g)quinoline-10,11-diol
(R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo(de,g)quinoline-10,11-diol
VR004
VR-400
Apomorphine (R,-)
Tocris-2073
APOMORPHINE [MI]
(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrate;hydrochloride
Prestwick0_000101
Prestwick1_000101
Prestwick2_000101
Prestwick3_000101
APOMORPHINE [HSDB]
Biomol-NT_000019
GTPL33
APOMORPHINE [VANDF]
APOMORPHINUM [HPUS]
SCHEMBL8541
APOMORPHINE [WHO-DD]
BSPBio_000082
SPBio_002021
BPBio1_000092
BPBio1_001179
BDBM29644
cid_6852399
HMS2089C10
NH001
Tox21_110967
BDBM50001955
PDSP1_000780
PDSP2_001488
AKOS040740360
Tox21_110967_1
DB00714
FA44559
SMP1_000027
NCGC00025349-01
NCGC00025349-03
NCGC00025349-04
NCGC00025349-05
DA-50067
NS00126037
D07460
G91374
A727500
AE-641/11399027
EN300-18161186
Q269111
BRD-K76022557-001-01-3
BRD-K76022557-001-03-9
BRD-K76022557-003-02-7
BRD-K76022557-311-20-6
(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
(-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)
(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)
(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)
(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)
6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)
6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)
APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
(9R)-10-methyl-10-azatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-1(16),2(7),3,5,13(17),14-hexaene-3,4-diol
200-360-0
OR9