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6,7-Dimethoxy-2-phenylquinoxaline

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Identification
Molecular formula
C16H14N2O2
CAS number
2792-52-9
IUPAC name
6,7-dimethoxy-2-phenyl-quinoxaline
State
State

At room temperature, 6,7-Dimethoxy-2-phenylquinoxaline is in a solid state. It is usually handled as a crystalline powder.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.15
Boiling point (Celsius)
376.20
Boiling point (Kelvin)
649.35
General information
Molecular weight
266.30g/mol
Molar mass
266.2830g/mol
Density
1.2040g/cm3
Appearence

6,7-Dimethoxy-2-phenylquinoxaline typically appears as a solid, crystalline powder. Its color can range from off-white to pale yellow, depending on the purity and specific batch of the compound.

Comment on solubility

Solubility of 6,7-dimethoxy-2-phenyl-quinoxaline (C16H14N2O2)

The solubility of 6,7-dimethoxy-2-phenyl-quinoxaline can be intriguing due to its complex molecular structure. Understanding its solubility can be beautifully summarized with the following points:

  • Polarity: The presence of methoxy groups generally enhances solubility in polar solvents. However, the overall molecular structure dictates the compound's behavior in different media.
  • Solvent Interactions: This compound is likely more soluble in organic solvents such as ethanol and dichloromethane than in water.
  • Temperature Dependence: As with many organic compounds, its solubility may increase with temperature, emphasizing the need for temperature control during experiments.
  • pH Effects: Changes in the pH of the solvent may influence the ionization of certain groups within the molecule, further affecting solubility.

In summary, while 6,7-dimethoxy-2-phenyl-quinoxaline is expected to exhibit limited solubility in aqueous environments, it holds potential for solubility in organic solvents, offering valuable insights for applications in chemical processes and pharmaceuticals.

Interesting facts

Interesting Facts about 6,7-Dimethoxy-2-phenyl-quinoxaline

6,7-dimethoxy-2-phenyl-quinoxaline is a fascinating compound, primarily due to its structural characteristics and potential applications. Here are some engaging facts about this compound:

  • Quinoxaline Derivative: This compound is a member of the quinoxaline family, which are bicyclic compounds featuring two nitrogen atoms in the ring. These types of molecules are known for their diverse biological activities.
  • Biological Significance: Quinoxaline derivatives have drawn considerable attention in medicinal chemistry due to their pharmacological properties. For instance, they can act as:
    • Antimicrobial agents
    • Antitumor compounds
    • Neuroprotective agents
  • Structure-Activity Relationship: The presence of the methoxy groups at the 6 and 7 positions enhances the compound's lipophilicity, aiding in its ability to cross biological membranes. The phenyl group attached at the 2-position may also contribute to its biological activity by providing additional electron-donating characteristics that can stabilize interactions with target proteins.
  • Research Frontiers: Scientists are actively exploring the potential of this compound in various fields, including:
    • Cancer therapies
    • Neurological disorders
    • Innovative synthetic pathways
  • Future Directions: Ongoing research aims to optimize the synthesis of derivatives of 6,7-dimethoxy-2-phenyl-quinoxaline, which may lead to the discovery of new drugs. Research indicates that modifying the substituents on the quinoxaline backbone can lead to enhanced efficacy and reduced side effects.

In conclusion, the compound 6,7-dimethoxy-2-phenyl-quinoxaline stands out due to its unique molecular structure and promising biological applications. As research continues, this compound could play a significant role in advancing medicinal chemistry and therapeutic strategies.

Synonyms
146535-11-7
Tyrphostin AG 1296
6,7-dimethoxy-2-phenylquinoxaline
AG-1296
AG 1296
6,7-Dimethoxy-3-phenylquinoxaline
Quinoxaline, 6,7-dimethoxy-2-phenyl-
ag1296
Tyrphostin AG1296
Tyrphostin AG-1296
MFCD00270913
CHEMBL71191
6,7-Dimethoxy-2-phenyl-quinoxaline
tyrphostin-AG1296
6,7-Dimethoxy-2-phenylquinozaline
tyrphostin-AG-1296
BiomolKI_000055
BiomolKI2_000061
BMK1-F7
BSPBio_001422
KBioGR_000142
KBioSS_000142
SCHEMBL595944
GTPL5915
CHEBI:93335
KBio2_000142
KBio2_002710
KBio2_005278
KBio3_000283
KBio3_000284
DTXSID70163393
Bio2_000142
Bio2_000622
HMS1361H04
HMS1791H04
HMS1989H04
HMS3229M21
HMS3402H04
HMS3653H21
BCP06928
EX-A4245
Tyrphostin AG 1296, >=98%
BDBM50154227
s8024
AKOS025287463
CCG-100659
Quinozaline, 6,7-dimethoxy-2-phenyl-
SDCCGSBI-0086718.P004
Tyrphostin AG 1296 (AG 1296)
IDI1_033892
NCGC00163386-01
NCGC00163386-02
NCGC00163386-03
NCGC00163386-04
AG-1296?
AS-62520
DA-68436
HY-13894
CS-0008498
D4601
SW220231-1
A10799
EN300-25893073
SR-03000001061
SR-03000001061-1
AG 1296 - CAS 146535-11-7
BRD-K76064317-001-03-2
BRD-K76064317-001-04-0
BRD-K76064317-001-07-3
BRD-K76064317-001-08-1
Q27074335
Z2216889477