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6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione

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Identification
Molecular formula
C8H4Cl2N2O2
CAS number
2372-66-5
IUPAC name
6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione
State
State

6,7-Dichloro-1,4-dihydroquinoxaline-2,3-dione is typically a solid at room temperature. Its crystalline form contributes to its solid state and structural integrity under normal conditions.

Melting point (Celsius)
275.00
Melting point (Kelvin)
548.15
Boiling point (Celsius)
585.00
Boiling point (Kelvin)
858.15
General information
Molecular weight
245.04g/mol
Molar mass
245.0400g/mol
Density
1.6500g/cm3
Appearence

6,7-Dichloro-1,4-dihydroquinoxaline-2,3-dione appears as a pale yellow crystalline solid. The compound's crystallinity contributes to its well-defined shape and bright yellow hue, which can intensify under specific conditions or when exposed to certain environmental factors, such as sunlight.

Comment on solubility

Solubility of 6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione

The solubility of 6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione (C8H4Cl2N2O2) is an intriguing aspect of this compound, primarily due to its molecular structure and functional groups. Here are several key points regarding its solubility:

  • Polarity: The presence of chlorine atoms and carbonyl groups contributes to the polarity of the molecule, affecting its solubility in various solvents.
  • Solvent Compatibility: It is generally more soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF) compared to water.
  • Temperature Dependency: As with many compounds, solubility can increase with temperature; therefore, heating the solvent may enhance solubility.
  • pH Sensitivity: The solubility might also be affected by the pH of the solution, especially if the compound can ionize under certain conditions.

In conclusion, while 6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione exhibits limited solubility in water, careful choice of solvent and conditions can lead to favorable dissolution characteristics. As always, empirical data should be sought for practical applications, as theoretical predictions may not encompass all influencing factors.

Interesting facts

Interesting Facts about 6,7-Dichloro-1,4-Dihydroquinoxaline-2,3-Dione

6,7-Dichloro-1,4-dihydroquinoxaline-2,3-dione is a fascinating compound that has garnered attention in various fields of research. Here are some intriguing aspects of this chemical:

  • Biological Activity: This compound exhibits significant biological properties, making it a subject of interest in pharmaceutical research. It has shown potential as an inhibitory agent against specific enzymes, which could lead to new therapeutic approaches in treating various diseases.
  • Synthesis: The synthesis of 6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione involves intricate organic reactions that showcase the versatility of organic chemistry techniques. This includes reactions such as cyclization and chlorination, highlighting the creativity often required in synthetic methodologies.
  • Quinoxaline Derivatives: As a member of the quinoxaline family, this compound is closely related to other derivatives that exhibit diverse pharmacological activities. Exploring these derivatives can lead to the discovery of new drugs with enhanced efficacy and safety profiles.
  • Research Applications: The compound has been utilized in various scientific studies, particularly in investigating mechanisms of action at the molecular level. Understanding its interactions with biological targets can provide insight into drug design and development.
  • Environmental Considerations: As with many chlorinated organic compounds, understanding the environmental impact and degradation pathways of 6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione is crucial. Researchers are actively studying its fate in the environment to ensure safe handling and application.

In summary, 6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione serves as an excellent example of how specific molecular structures can lead to remarkable biological activities. Its versatile synthetic routes and potential applications in drug development make it a compound of continuous interest within the scientific community.

Synonyms
25983-13-5
6,7-Dichloroquinoxaline-2,3(1H,4H)-dione
6,7-DICHLORO-1,4-DIHYDRO-2,3-QUINOXALINEDIONE
6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione
DCQX
2,3-Dihydroxy-6,7-dichloroquinoxaline
MFCD00078575
6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione
CHEMBL284028
6,7-dichloroquinoxaline-2,3-diol
Spectrum_001661
SpecPlus_000650
Lopac-D-133
Spectrum2_000537
Spectrum3_001668
Spectrum4_000630
Spectrum5_001426
Biomol-NT_000181
2,3-Quinoxalinedione,6,7-dichloro-1,4-dihydro-
Lopac0_000418
BSPBio_003455
KBioGR_001220
KBioSS_002141
2,3-Quinoxalinedione, 6,7-dichloro-1,4-dihydro-
DivK1c_006746
SCHEMBL463608
SPECTRUM1504232
SPBio_000553
BPBio1_001174
SCHEMBL8122389
BDBM22778
KBio1_001690
KBio2_002141
KBio2_004709
KBio2_007277
KBio3_002675
DTXSID70274337
AVBSIKMUAFYZAV-UHFFFAOYSA-N
CHEBI:113553
6,7-Dichloro-2,3-quinoxalinedione
BDBM50417135
CCG-39598
AKOS015850366
NCGC00015311-01
NCGC00015311-02
NCGC00015311-03
NCGC00015311-04
NCGC00015311-05
NCGC00093842-01
NCGC00093842-02
NCGC00093842-03
NCGC00095336-01
NCGC00095336-02
BS-25366
PD001218
SY105439
DB-014624
CS-0038531
D-133
EU-0100418
6,7-dichloro-quinoxaline-2,3(1H,4H)-dione
2-3-DIHYDROXY-6-7-DICHLOROQUINOXALINE
SR-01000075444
SR-01000075444-1
BRD-K80576679-001-03-1
Q27194449
6,7-dichloro-1,2,3,4-tetrahydroquinoxaline-2,3-dione