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Tetrahydrocannabinol (THC)

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Identification
Molecular formula
C21H30O2
CAS number
1972-08-3
IUPAC name
6,6,9-trimethyl-3-pentyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
State
State

Tetrahydrocannabinol is typically found as a sticky resin or oil at room temperature.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
157.00
Boiling point (Kelvin)
430.15
General information
Molecular weight
314.47g/mol
Molar mass
314.4690g/mol
Density
1.0040g/cm3
Appearence

Tetrahydrocannabinol is a yellowish oil or resin depending on the form. It is poorly soluble in water and has a sticky texture. In its pure form, it can appear as crystals.

Comment on solubility

Solubility of 6,6,9-trimethyl-3-pentyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol (C21H30O2)

The solubility of 6,6,9-trimethyl-3-pentyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol is influenced by multiple factors, primarily its chemical structure and overall polarity. Being a polycyclic compound with multiple alkyl groups, it exhibits interesting solubility characteristics:

  • Nonpolar Nature: The compound contains a significant amount of hydrocarbon (alkyl) structure, which typically results in low solubility in polar solvents like water.
  • Solubility in Organic Solvents: Due to its hydrophobic nature, it is expected to be soluble in nonpolar organic solvents such as hexane, toluene, or chloroform.
  • Temperature Dependency: The solubility may increase with temperature, which is common for many organic compounds, as higher temperatures can disrupt intermolecular forces.

Overall, while precise solubility data may be limited, it can be inferred that the solubility of this compound will be significantly higher in organic solvents compared to aqueous environments. Understanding these solubility properties is crucial for applications in areas such as pharmacology and material science, where solvent interactions can determine the efficacy and behavior of the compound in practical scenarios.

Interesting facts

Exploring 6,6,9-trimethyl-3-pentyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol

This intriguing compound, often referenced in the context of natural products, is a part of a larger family known as cannabinoids. Here are some fascinating aspects:

  • Natural Origins: This compound is structurally related to various cannabinoids found in the cannabis plant, suggesting potential therapeutic implications.
  • Biological Activity: It may exhibit various biological activities, including anti-inflammatory, analgesic, and neuroprotective effects, making it a subject of interest in pharmacological research.
  • Synthetic Routes: The synthesis of this compound can be achieved through various organic reactions, showcasing the versatility of synthetic organic chemistry in constructing complex molecular architectures.
  • Structure-Activity Relationship (SAR): Understanding the SAR for this compound may reveal how the specific arrangement of its atoms affects its interaction with biological systems, providing insights for drug design.
  • Legal Status: As with many cannabinoid-related compounds, the legal status can vary by region, influencing research and commercial opportunities.

Overall, 6,6,9-trimethyl-3-pentyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol represents a bridge between nature and synthetic chemistry, allowing scientists to explore its potential applications in medicine and beyond.

Synonyms
.delta.6-THC
delta-8-tetrahydrocannabinol
.DELTA.1(6)-Tetrahydrocannabinol
(-)-.DELTA.6-Tetrahydrocannabinol
.DELTA.8-trans-Tetrahydrocannabinol
.DELTA.8-THC
NSC 134453
Cannabinol, .DELTA.1(6)-tetrahydro-
6,6,9-trimethyl-3-pentyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
(-)-.DELTA.8-trans-Tetrahydrocannabinol
.DELTA.6-Tetrahydrocannabinol
.DELTA.8-Tetrahydrocannabinol
14132-18-4
.DELTA.8-l-Tetrahydrocannabinol
l-.DELTA.8-Tetrahydrocannabinol
(-)-.DELTA.8-Tetrahydrocannabinol
6a,7,10,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-6h-dibenzo[b,d]pyran-1-ol
1-trans-.DELTA.8-Tetrahydrocannabinol
.DELTA.1(6)-trans-Tetrahydrocannabinol
(-)-trans-.DELTA.8-Tetrahydrocannabinol
Cannabinol, 1-trans-.DELTA.8-tetrahydro-
Cannabinol, delta1(6)-tetrahydro-
8-Tetrahydrocannabinol
6H-Dibenzo(b,d)pyran-1-ol, 6a,7,10,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR-trans)-
6H-Dibenzo(b,d)pyran-1-ol, 6a,7,10,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, trans-(-)-
6H-Dibenzo[b,d]pyran-1-ol, 6a,7,10,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR-trans)-
6H-Dibenzo[b,d]pyran-1-ol, 6a,7,10,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, trans-(-)-
trans-.DELTA.8-Tetrahydrocannabinol
NSC-134453
delta6-THC
(-)-.DELTA.6-3,4-trans-Tetrahydrocannabinol
.delta.-8-THC
.delta.-(sup6)-THC
.delta.-(sup8)-THC
CHEMBL46518
DELTA8-l-Tetrahydrocannabinol
DivK1c_000978
l-DELTA8-Tetrahydrocannabinol
SCHEMBL120839
delta1(6)-Tetrahydrocannabinol
(-)-delta6-Tetrahydrocannabinol
delta8-trans-Tetrahydrocannabinol
HMS503C17
KBio1_000978
NINDS_000978
6H-Dibenzo(b,d)pyran-1-ol, 6a,7,10,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR,10aR)-
EDC80578
1-trans-DELTA8-Tetrahydrocannabinol
NSC134453
(-)-delta8-trans-Tetrahydrocannabinol
(-)-trans-delta8-Tetrahydrocannabinol
IDI1_000978
Cannabinol, 1-trans-DELTA8-tetrahydro-
1-trans-.delta.-(sup8)-Tetrahydrocannabinol
NS00017747
(-)-.delta.-(sup8)-trans-Tetrahydrocannabinol
Cannabinol, 1-trans-.delta.-(sup8)-tetrahydro-
6H-Dibenzo[b, 6a,7,10,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-
6,6,9-Trimethyl-3-pentyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol, trans-(-) #
6H-Dibenzo[b, 6a,7,10,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR-trans)-
6H-Dibenzo[b, 6a,7,10,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, trans-(-)-