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6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole

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Identification
Molecular formula
C11H12N2S
CAS number
3622-77-3
IUPAC name
6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole
State
State

At room temperature, 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole is in a solid state. It remains stable in air and does not sublimate or melt at room conditions.

Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
372.00
Boiling point (Kelvin)
645.15
General information
Molecular weight
202.29g/mol
Molar mass
202.2900g/mol
Density
1.2500g/cm3
Appearence

The compound appears as a crystalline solid with a light yellow to off-white color. Its solid state is characterized by a crystalline structure which can be further described by crystallography studies, often available as fine powders or small granules.

Comment on solubility

Solubility of 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole (C11H12N2S)

The solubility of 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole in various solvents can provide insights into its potential applications. Understanding its solubility behavior is crucial for industries that utilize this compound. Here are some key points to consider:

  • Solvent Polarity: The solubility of this compound may vary significantly with changes in solvent polarity. Generally, non-polar solvents like benzene may dissolve this compound better than highly polar solvents.
  • Temperature Influence: Increasing temperature often enhances the solubility of organic compounds, including 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole. Higher temperatures can lead to increased kinetic energy, allowing more solute particles to overcome solvation barriers.
  • Complex Formation: This compound might engage in complexation with certain solvents, which can affect its overall solubility. Such interactions can be critical in fine-tuning solubility for specific applications.
  • Nature of the Compound: With a unique thiazole structure and various substituents, its specific functional groups can significantly affect solubility. For example, the presence of aromatic rings may enhance solubility in organic solvents.

In conclusion, the solubility of 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole is influenced by multiple factors, including solvent type, temperature, and molecular interactions. Understanding these parameters is essential for optimizing its use in various chemical reactions and formulations.

Interesting facts

6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole

6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole is a fascinating compound that belongs to a unique class of heterocyclic aromatic compounds. Its complex structure showcases the intriguing interplay between various chemical functionalities. Here are some interesting facts about this intriguing molecule:

  • Heterocyclic Nature: This compound features a thiazole ring fused with an imidazole structure, making it a part of heterocyclic chemistry, which is pivotal in the design of many biologically active molecules.
  • Pharmacological Significance: Compounds containing the imidazole and thiazole moieties are known for their diverse biological activities, including anti-inflammatory, antifungal, and antiviral properties. This makes 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole a promising candidate for pharmaceutical research.
  • Reactivity: The presence of nitrogen and sulfur atoms in the structure enhances its reactivity, allowing for potential modifications that can lead to new derivatives with tailored properties.
  • Applications in Material Science: Beyond medicinal chemistry, the unique properties of this compound may find applications in developing new materials, such as sensors or catalysts, due to its electronic properties and stability.
  • Research Tool: In the laboratory, 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole can serve as a critical building block for synthesizing more complex molecules, aiding in the understanding of chemical reactivity and structure-property relationships.

As you delve into the study of this compound, remember that its unique attributes could lead to significant discoveries in both chemistry and biochemistry. The possibilities within this compound, from medicinal implications to material innovations, truly highlight the endless potential of heterocyclic compounds in modern science.

Synonyms
TETRAMISOLE
5036-02-2
tetramizole
6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
Tetramisol
Ascaverm
Levamisole dl-form
C8M7RFE4NO
6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole
Imidazo[2,1-b]thiazole, 2,3,5,6-tetrahydro-6-phenyl-
CHEBI:77278
Tetramisole (INN)
(-)-Tetramisole hydrochloride
NSC-102063
TETRAMISOLE [INN]
L-Tetramisole; Lepuron; Levamisol; Levamisole
R-8299
dl-Tetramisole
6-Phenyl-2,3,5,6-tetrahydroimidazo(2,1-b)thiazole
Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-
MFCD00792481
Levamisol 100 microg/mL in Acetonitrile
Ascaverm (TN)
2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole; (+/-)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole;
Tetramisole [INN:BAN]
Prestwick0_000545
Prestwick1_000545
Prestwick2_000545
Prestwick3_000182
Prestwick3_000545
UNII-C8M7RFE4NO
Tetramisol [INN-Spanish]
Tetramisolum [INN-Latin]
Lopac0_001194
BSPBio_000103
BSPBio_000589
TETRAMISOLE [WHO-DD]
MLS006011861
SCHEMBL167819
SPBio_002510
BPBio1_000115
BPBio1_000649
CHEMBL277775
Tetramisole [veterinary] (TN)
LEVAMISOLE DL-FORM [MI]
HY-B1194A
DTXSID20860143
HMS1674C22
Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, (+-)-
EINECS 225-729-3
EINECS 229-667-8
ICI 50627
NSC614927
STL019093
Tetramisole, Tetramisole Hydrochloride
AKOS000605651
AKOS022087568
AKOS022142451
CCG-205268
NSC 102063
NSC-614927
SB67394
SDCCGSBI-0051161.P003
NCGC00015620-03
NCGC00015620-04
NCGC00015620-14
NCGC00015620-17
NCGC00162225-01
NCGC00162363-01
AC-11604
SMR001550472
SY107591
SBI-0051161.P002
DB-071180
NS00081384
D08576
BRD-A46393198-003-04-2
BRD-A46393198-003-10-9
BRD-A46393198-003-15-8
BRD-A46393198-003-16-6
Q27146858
2,3,5,6-tetrahydro-6-phenylimidazo-[2,1-b]-thiazole
6-phenyl-2,3,5,6-tetrahydro imidazo [2,1-b]thiazole
(-)-2,3,5,6-Tetrahydro-6-phenylimidazol[2,1-b]thiazole
(+/-)-2,3,5,6-TETRAHYDRO-6-PHENYLIMIDAZO(2,1-B)THIAZOLE
6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole-, (S)-