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Harmolol

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Identification
Molecular formula
C18H17NO3
CAS number
6027-54-9
IUPAC name
6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol
State
State

Harmolol is typically found in a solid state at room temperature.

Melting point (Celsius)
304.00
Melting point (Kelvin)
577.15
Boiling point (Celsius)
402.00
Boiling point (Kelvin)
675.15
General information
Molecular weight
299.33g/mol
Molar mass
299.3320g/mol
Density
1.2700g/cm3
Appearence

Harmolol appears as a crystalline solid which may exhibit a colorless to pale yellow hue. Crystalline forms generally allow distinct visibility of solid particles.

Comment on solubility

Solubility of 6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol (C18H17NO3)

The solubility of 6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol is a multifaceted characteristic influenced by its unique molecular structure.

  • Polarity: The presence of hydroxyl (-OH) groups in the compound increases its polarity, typically enhancing its solubility in polar solvents such as water.
  • Solvent Interaction: Hydrogen bonding capabilities due to these hydroxyl groups allow for greater interaction with water molecules, promoting solubility in aqueous solutions.
  • Organic Solvents: Conversely, the non-polar regions of the molecule may make it less soluble in non-polar solvents. Thus, it is likely to show moderate solubility in organic solvents such as ethanol and methanol, which have some polar characteristics.

In summary, while the compound exhibits some degree of solubility in water due to its polar functional groups, its solubility profile varies significantly with organic solvents. Understanding these interactions not only aids in practical applications but also enhances the compound's versatility in chemical formulations.

Interesting facts

Exploring 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol

6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol is a fascinating compound that belongs to the class of dibenzoquinoline derivatives. As a compound of interest in medicinal chemistry, it has bees studied for potential therapeutic applications. Here are some intriguing aspects of this compound:

  • Structural Complexity: The compound features a complex polycyclic structure, which contributes to its unique chemical behavior and biological activities. The presence of multiple fused rings allows for interesting stereochemistry.
  • Biological Activity: Preliminary research indicates potential interactions with various biological targets, making this compound a candidate for further pharmacological exploration.
  • Synthetic Routes: The synthesis of such intricate molecules often involves multiple synthetic steps, employing various reactions and techniques such as cyclization and functional group modifications.
  • Research Interest: Scientists are keenly interested in compounds like this for their potential roles in drug development, particularly in areas such as oncology and neurology.
  • Analytical Techniques: The analysis of this compound might utilize techniques like Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS), and chromatographic methods to unravel its structure and purity.

As one advances in the realm of organic chemistry, understanding compounds like 6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol not only enriches one’s knowledge but also highlights the intricate connections between structure and function in drug design. It's a testament to the creativity and precision involved in synthesizing bioactive compounds!

Synonyms
2-Hydroxyapomorphine
64781-18-6
4H-Dibenzo(de,g)quinoline-2,10,11-triol, 5,6,6a,7-tetrahydro-6-methyl-
6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol
SCHEMBL140170
2,10,11-trihydroxyaporphine
DTXSID70983391
NCGC00162155-01
NCGC00162155-02
PD034487