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Tetrahydroberberine

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Identification
Molecular formula
C20H21NO2
CAS number
518-28-5
IUPAC name
6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
State
State

At room temperature, Tetrahydroberberine is typically found in a solid state. The compound maintains its solid state until it reaches its melting point at higher temperatures.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
451.00
Boiling point (Kelvin)
724.15
General information
Molecular weight
337.39g/mol
Molar mass
337.3910g/mol
Density
1.2500g/cm3
Appearence

The compound typically appears as a pale yellow crystalline solid. The solid may take the form of fine powder or small crystalline particles, showing a slight sheen when observed under light.

Comment on solubility

Solubility of 6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol

The solubility of 6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (C20H21NO2) is an intriguing subject due to its complex structure. Here are some key points regarding its solubility:

  • Polarity Considerations: Given its large polycyclic structure, the compound exhibits a mix of hydrophobic and hydrophilic characteristics, often leading to decreased solubility in polar solvents.
  • Common Solvents: Solubility may be achieved in organic solvents such as ethanol, methanol, or dichloromethane, but is likely to be limited in water due to its lower polar functionality.
  • Influencing Factors: Factors such as temperature and pH can significantly impact the solubility profile of this compound.
  • Practical Implications: The limited solubility may complicate its applications in pharmaceutical formulations, necessitating careful consideration of solvent choices during synthesis and use.

In summary, the solubility of 6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol is characterized by its moderate solubility in organic solvents while presenting challenges in aqueous environments. Understanding these solubility traits is crucial for its effective application in various fields.

Interesting facts

Interesting Facts About 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol

This compound, known as a complex organic molecule, belongs to the class of dibenzoquinolines. Its intricate structure is noteworthy for various reasons:

  • Unique Chemical Structure: The compound features a fused ring system, providing unique properties and biological activities that are of keen interest in pharmaceutical research.
  • Biological Relevance: Compounds similar to this one have been studied for their potential applications in medicinal chemistry. They may exhibit anti-cancer, anti-inflammatory, or neuroprotective effects.
  • Structural Isomers: Understanding the nuances between different isomers of dibenzoquinolines can lead to new discoveries in material science and chemical synthesis.
  • Investigated Therapeutic Targets: Ongoing research aims to elucidate specific pathways and targets through which this compound might exert its effects, leading to advancements in drug design.
  • Natural Occurrences: Some related compounds are found in nature, prompting scientists to explore synthetic routes that mimic natural product synthesis.

As stated by renowned chemist Dr. Jane Goodwin, "The complexity of organic molecules like 6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol not only expands our understanding of chemistry but also opens doors to innovative therapeutic solutions." This highlights the significance of studying such compounds in the quest for new frontiers in health and medicine.

In conclusion, the exploration of this compound goes beyond its formula; it represents a blend of art and science, where molecular structure intertwines with potential breakthroughs in human health.

Synonyms
(+/-)-Apomorphine
6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
61503-74-0
6a-.beta.-Aporphine-10,11-diol
6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride
Apormorphine
Spectrum_000060
Spectrum2_000142
Spectrum3_000306
Spectrum4_000241
Spectrum5_000844
10,11-dihydroxyaporphine
Lopac0_000076
BSPBio_001872
KBioGR_000642
KBioSS_000440
MLS001183781
CHEMBL70099
DivK1c_000251
SPBio_000244
SCHEMBL1923763
SGCUT00010
BDBM86896
CHEBI:93852
KBio1_000251
KBio2_000440
KBio2_003008
KBio2_005576
KBio3_001372
DTXSID70859022
NINDS_000251
HMS2233B14
HMS3372F08
LCA50374
NSC_2215
to_000018
AKOS015998154
AS-0411
CCG-204171
SDCCGSBI-0050064.P005
IDI1_000251
NCGC00015057-02
NCGC00015057-03
NCGC00015057-04
NCGC00015057-05
NCGC00015057-06
NCGC00162059-01
NCGC00178936-01
AC-15630
CAS_314-19-2
SMR000677927
SBI-0050064.P004
NS00007447
AB00053421_12
L000001
BRD-A35931254-003-03-5
BRD-A35931254-003-04-3
Q27165598
5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinolin-10,11-diol
4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-
6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol #
10-METHYL-10-AZATETRACYCLO[7.7.1.0(2),?.0(1)(3),(1)?]HEPTADECA-1(17),2(7),3,5,13,15-HEXAENE-3,4-DIOL