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Validamycin A

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Identification
Molecular formula
C20H35N2O13
CAS number
37248-47-8
IUPAC name
6-methyl-5-[[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]tetrahydropyran-2,3,4-triol
State
State

Validamycin A is typically found in a solid state at room temperature. As a solid, it appears as a stable crystalline powder and should be stored in a cool, dry place to maintain its stability and prevent decomposition.

Melting point (Celsius)
246.00
Melting point (Kelvin)
519.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
497.51g/mol
Molar mass
497.5200g/mol
Density
1.6127g/cm3
Appearence

Validamycin A typically appears as a white to off-white crystalline powder. It is hygroscopic and may absorb moisture from the air, which can affect its consistency and appearance.

Comment on solubility

Solubility of 6-methyl-5-[[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]tetrahydropyran-2,3,4-triol

The solubility of the compound 6-methyl-5-[[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]tetrahydropyran-2,3,4-triol (C20H35N2O13) is influenced by several factors, primarily its chemical structure and the presence of multiple functional groups.

Factors Affecting Solubility:

  • Polarity: The numerous hydroxyl (-OH) groups present within the molecule contribute significantly to its overall polarity, enhancing solubility in polar solvents, particularly water.
  • Hydrogen Bonding: The capability of -OH groups to form hydrogen bonds facilitates intermolecular interactions with solvents, further improving solubility.
  • Molecular Size: With a relatively large molecular size, the solubility can be limited in non-polar solvents due to steric hindrance and reduced interactions.

Typically, compounds with multiple hydroxyl groups exhibit high solubility in water, and this is likely the case for this particular structure. Many similar compounds are known to be soluble due to their polar nature and ability to engage in hydrogen bonding.

In summary, one can expect that 6-methyl-5-[[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]tetrahydropyran-2,3,4-triol will display considerable solubility in polar solvents while being less soluble in non-polar environments, which is a common trend observed with similar chemical classes.

Interesting facts

Interesting Facts about 6-methyl-5-[[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]tetrahydropyran-2,3,4-triol

The compound 6-methyl-5-[[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]tetrahydropyran-2,3,4-triol represents a fascinating combination of chemical structures and functional groups. It belongs to a class of compounds that exhibit significant biological activity and potential therapeutic applications. Here are some intriguing aspects:

  • Complex Structure: The molecule is characterized by a complex arrangement involving both tetrahydropyran and cyclohexene moieties, leading to interesting stereochemistry and reactivity.
  • Natural Products: This compound closely resembles certain natural products, which are often the basis for drug discovery. Such compounds can exhibit antimicrobial and anticancer properties.
  • Hydroxymethyl Group: The presence of multiple hydroxymethyl groups not only affects the solubility but may also enhance the molecule's interaction with biological targets through hydrogen bonding.
  • Research Interest: Scientists are keen on exploring the synthesis pathways for this compound, which can help in understanding the mechanisms behind its biological activities.

As a scientist, exploring the intricacies of this compound can lead to exciting discoveries in the realm of medicinal chemistry. The study of such compounds contributes to our understanding of how small changes in molecular structures can lead to varying biological functions, making them invaluable in the design of novel pharmaceuticals.

In the words of a renowned chemist, "The beauty of chemistry lies in the connections we make, not only between atoms and molecules, but also between ideas and discoveries." Engaging with compounds like this one can foster a deeper appreciation for the dynamic and interconnected nature of chemical science.

Synonyms
SCHEMBL14408998
PD041634