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6-Methoxy-8-nitroquinoline

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Identification
Molecular formula
C10H8N2O3
CAS number
6850-58-2
IUPAC name
6-methoxy-8-nitro-quinoline
State
State

At room temperature, 6-Methoxy-8-nitroquinoline is a solid. Its crystalline form contributes to its stable manifestation as a solid under standard conditions.

Melting point (Celsius)
179.00
Melting point (Kelvin)
452.15
Boiling point (Celsius)
335.00
Boiling point (Kelvin)
608.15
General information
Molecular weight
218.19g/mol
Molar mass
218.1910g/mol
Density
1.3897g/cm3
Appearence

6-Methoxy-8-nitroquinoline presents as a yellow crystalline solid. The compound's coloration is characteristic due to the presence of the nitro functional group, which often imparts a yellow hue.

Comment on solubility

Solubility of 6-Methoxy-8-Nitro-Quinoline

6-Methoxy-8-nitro-quinoline, a compound with a complex molecular structure, presents unique solubility characteristics. The solubility behavior of this compound can be influenced by several factors:

  • Polarity: The presence of both methoxy and nitro groups contributes to its overall dipole moment, which affects its solubility in polar solvents.
  • Solvent Choice: Typically, this compound may dissolve better in organic solvents such as ethanol or dimethyl sulfoxide (DMSO), rather than in water due to the hydrophobic nature of the quinoline structure.
  • Temperature: Higher temperatures might enhance solubility for certain organic compounds, allowing greater interaction between solute and solvent molecules.
  • pH Conditions: The solubility can also be affected by the pH of the solution; in acidic or basic environments, the ionization of the various functional groups can significantly alter solubility.

In conclusion, while 6-methoxy-8-nitro-quinoline possesses some level of solubility in organic solvents, it may remain largely insoluble in aqueous environments. Understanding these aspects can aid in predicting its behavior in various chemical applications.

Interesting facts

Interesting Facts About 6-Methoxy-8-Nitro-Quinoline

6-Methoxy-8-nitro-quinoline is a fascinating compound that belongs to the quinoline family, which is recognized for its diverse applications in chemistry, pharmaceuticals, and material science. Here are some illuminating facts about this compound:

  • Structural Significance: The presence of both a methoxy group and a nitro group on the quinoline ring contributes to its unique reactivity and functional properties. This configuration can lead to interesting interactions in various chemical environments.
  • Pharmacological Potential: Compounds related to quinoline often exhibit significant biological activity. Research into derivatives of this compound might reveal potential in areas such as anti-malarial and anti-cancer therapies, showcasing the compound as a promising candidate for drug discovery.
  • Fluorescent Properties: Some quinoline derivatives display fluorescent characteristics, which can be advantageous in biological imaging applications. This could potentially allow scientists to visualize cellular processes and the pathways of certain drugs.
  • Importance in Synthesis: 6-Methoxy-8-nitro-quinoline can serve as a valuable intermediate in the synthesis of other complex chemical entities. Its structural framework makes it a key building block in organic synthesis.
  • Historical Context: Quinoline itself has been widely studied since its discovery in the 19th century. The continued exploration of its derivatives, such as 6-methoxy-8-nitro-quinoline, reflects the evolving nature of chemical research and its applications.

In summary, 6-methoxy-8-nitro-quinoline stands out as more than just a chemical compound; it represents a rich area of study with potential implications in multiple fields of science and technology. As research progresses, who knows what new discoveries await around the corner?

Synonyms
6-Methoxy-8-nitroquinoline
85-81-4
QUINOLINE, 6-METHOXY-8-NITRO-
8-Nitro-6-methoxyquinoline
6-Methoxy-8-nitro-quinoline
Methyl 8-nitro-6-quinolyl ether
NSC 1883
EINECS 201-633-7
ATS412O1XO
BRN 0168992
AI3-16314
NSC-1883
MFCD00006802
UNII-ATS412O1XO
MIMUSZHMZBJBPO-UHFFFAOYSA-
DTXSID50234050
5-21-03-00248 (Beilstein Handbook Reference)
METHOXY-8-NITROQUINOLINE, 6-
PRIMAQUINE DIPHOSPHATE IMPURITY B [EP IMPURITY]
PRIMAQUINE DIPHOSPHATE IMPURITY B (EP IMPURITY)
NSC1883
Oprea1_836531
CHEMBL166980
SCHEMBL1378967
DTXCID50156541
6-Methoxy-8-nitroquinoline, 99%
STK075103
AKOS005390929
NCGC00161730-01
AS-11089
SY004660
DB-056883
CS-0043044
M2057
NS00039068
EN300-119579
SR-01000312011
CU-00000000158-1
SR-01000312011-1
Q27274117
Z1509515579