Skip to main content

6-Fluoro-spiro[chromane-4,4'-imidazolidine]-2-carboxamide

ADVERTISEMENT
Identification
Molecular formula
C13H11FN2O3
CAS number
161326-98-1
IUPAC name
6-fluoro-2',5'-dioxo-spiro[chromane-4,4'-imidazolidine]-2-carboxamide
State
State

The compound is a solid at room temperature. It has a stable molecular structure, contributing to its solid state under standard conditions of temperature and pressure. Its crystalline nature is typical of many organic compounds containing aromatic systems and amide functionalities.

Melting point (Celsius)
234.00
Melting point (Kelvin)
507.15
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.15
General information
Molecular weight
268.23g/mol
Molar mass
268.2310g/mol
Density
1.4823g/cm3
Appearence

The compound appears as a white crystalline solid. Its structure contains a spiro linkage between a chromane and an imidazolidine ring, which might affect its crystallinity and reflective properties, offering a somewhat glossy appearance depending on crystal faceting.

Comment on solubility

Solubility of 6-fluoro-2',5'-dioxo-spiro[chromane-4,4'-imidazolidine]-2-carboxamide

The solubility of the compound 6-fluoro-2',5'-dioxo-spiro[chromane-4,4'-imidazolidine]-2-carboxamide (C13H11FN2O3) is influenced by several factors, and its behavior in various solvents presents a fascinating subject for study. Here are some key points regarding its solubility:

  • Polarity: Given the molecular structure, the presence of polar functional groups such as the carboxamide may enhance solubility in polar solvents like water and ethanol.
  • Hydrogen Bonding: The potential for intramolecular and intermolecular hydrogen bonding can impact solubility. The carboxamide group is particularly effective at forming hydrogen bonds.
  • Solvent Effects: It is expected that this compound may be soluble in organic solvents due to its hydrophobic chromane component. Solubility in solvents like dimethyl sulfoxide (DMSO) or dimethylformamide (DMF) may be significant.
  • Temperature Dependence: Solubility can also be temperature-dependent; typically, solubility increases with temperature for most solid compounds.

In summary, while specific solubility data might be scarce, the structure of 6-fluoro-2',5'-dioxo-spiro[chromane-4,4'-imidazolidine]-2-carboxamide hints at a complex solubility profile. Future studies would provide valuable insights into its solvation behavior and potential applications in various fields.

Interesting facts

Interesting Facts about 6-Fluoro-2',5'-dioxo-spiro[chromane-4,4'-imidazolidine]-2-carboxamide

This compound, known as 6-fluoro-2',5'-dioxo-spiro[chromane-4,4'-imidazolidine]-2-carboxamide, is a fascinating example in the realm of organic chemistry, particularly due to its unique structure and potential applications. Here are some interesting aspects:

  • Complex Structure: The spirocyclic nature of this compound combines features from both chromane and imidazolidine, contributing to its distinctive properties that may enhance its reactivity and biological activity.
  • Fluorine Substitution: The presence of a fluorine atom is notable, as fluorinated compounds often exhibit improved pharmacological properties, such as increased metabolic stability and lipophilicity, making them interesting candidates for drug design.
  • Potential Applications: Due to its structural characteristics, compounds like this are often explored for their potential in pharmaceuticals, especially in developing treatments for various diseases, including cancer and neurodegenerative disorders.
  • Synthetic Pathways: The synthesis of complex organic compounds like this often involves intricate multi-step processes, showcasing the creativity and innovation in synthetic organic chemistry. The methodologies used can also be a focal point for research and development in synthetic strategies.

As scientists continue to explore the ramifications of such compounds, it is exciting to consider future studies that may reveal even more about their utility and significance in medicinal chemistry. The blend of both traditional and modern approaches in synthesizing this compound underscores the dynamism in the field of chemistry.

Synonyms
105300-43-4
6-fluoro-2',5'-dioxo-2,3-dihydrospiro[chromene-4,4'-imidazolidine]-2-carboxamide
6-fluoro-2',5'-dioxospiro[2,3-dihydrochromene-4,4'-imidazolidine]-2-carboxamide
6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide
WAAPEIZFCHNLKK-UHFFFAOYSA-N
NCGC00167477-01
MLS006011477
CHEMBL408742
SCHEMBL1219758
DTXSID40861334
STK692948
AKOS000320338
Spiro(4H-1-benzopyran-4,4'-imidazolidine)-2-carboxamide, 6-fluoro-2,3-dihydro-2',5'-dioxo-
SMR004703265
SR-01000945184
SR-01000945184-1
BRD-A63752151-001-01-2
6-Fluoro-2a(2),5a(2)-dioxospiro[chroman-4,4a(2)-imidazolidine]-2-carboxamide