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6-Ethoxy-2,2,4-trimethyl-1,2-dihydroquinoline

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Identification
Molecular formula
C14H19NO
CAS number
91-53-2
IUPAC name
6-ethoxy-2,2,4-trimethyl-1H-quinoline
State
State

At room temperature, it exists as a liquid. This is common with many organic compounds that have significant alkyl substituents like ethoxy and trimethyl groups, which lower melting points.

Melting point (Celsius)
-50.00
Melting point (Kelvin)
223.15
Boiling point (Celsius)
283.00
Boiling point (Kelvin)
556.15
General information
Molecular weight
201.31g/mol
Molar mass
201.2910g/mol
Density
1.0113g/cm3
Appearence

The compound is typically a yellow to orange liquid.

Comment on solubility

Solubility of 6-ethoxy-2,2,4-trimethyl-1H-quinoline (C14H19NO)

The solubility of 6-ethoxy-2,2,4-trimethyl-1H-quinoline, a nitrogen-containing heterocyclic compound, can be categorized based on various factors such as polarity, intermolecular interactions, and environmental conditions. Generally speaking, the solubility characteristics of this compound can be summarized as follows:

  • Polarity: The presence of the ethoxy group introduces some polar character, but the overall structure is predominantly hydrocarbon-like, which tends to be less soluble in polar solvents.
  • Solvent Compatibility: This compound is likely to show increased solubility in organic solvents such as ethanol, acetone, and chloroform due to its hydrophobic regions outweighing its hydrophilic groups.
  • Temperature Influence: Like many organic compounds, increased temperature may enhance its solubility in organic solvents, allowing for better dissolution.
  • Applications: Understanding the solubility of this quinoline derivative is crucial for its use in pharmaceuticals and organic synthesis, where solvent choice impacts reaction efficiency.

In conclusion, while 6-ethoxy-2,2,4-trimethyl-1H-quinoline may not be highly soluble in water, its compatibility with various organic solvents offers valuable options for practical applications and further study. Maintaining an awareness of these solubility factors is essential for optimizing its use in scientific and industrial processes.

Interesting facts

Interesting Facts About 6-Ethoxy-2,2,4-trimethyl-1H-quinoline

6-Ethoxy-2,2,4-trimethyl-1H-quinoline, a fascinating member of the quinoline family, has garnered attention for its unique structure and potential applications. Quinoline derivatives like this one are known for their intriguing properties and versatile functionality in various fields, particularly in medicinal chemistry.

Key Features of 6-Ethoxy-2,2,4-trimethyl-1H-quinoline:

  • Structural Intricacies: The presence of multiple alkyl groups in its structure contributes to its stability and reactivity, making it an interesting compound for synthetic purposes.
  • Potential Bioactivity: Compounds in the quinoline class often exhibit a broad range of biological activities, including anti-inflammatory, antibacterial, and antimalarial properties. Studies on derivatives suggest a promising avenue for drug discovery.
  • Applications in Organic Synthesis: This compound can serve as a building block for synthesis of more complex molecules, potentially paving the way for innovative pharmaceutical compounds.
  • Fluorescent Properties: Some quinoline derivatives are known for their fluorescent properties, which can be harnessed in biochemical assays and materials science.

"Diversity in the structure leads to a wealth of opportunities for discovery." This assertion rings true in the world of chemical compounds like 6-ethoxy-2,2,4-trimethyl-1H-quinoline, where even subtle changes in molecular structure can lead to significant changes in physicochemical properties and biological activity.

As research continues, compounds like this one could uncover new therapeutic avenues or enhance existing methodologies in various scientific fields.

Synonyms
ethoxyquin
91-53-2
6-Ethoxy-2,2,4-trimethyl-1,2-dihydroquinoline
Ethoxyquine
Santoquin
Santoquine
Niflex
Antioxidant EC
Santoflex A
Santoflex AW
Stop-Scald
Dawe's nutrigard
Nix-Scald
Nocrack AW
Quinol ED
Aries Antox
Permanax 103
Amea 100
Niflex D
Antage AW
Nocrac AW
Ethoxychin
Alterungsschutzmittel EC
Ethoxyquin [ISO]
Quinoline, 6-ethoxy-1,2-dihydro-2,2,4-trimethyl-
Santoquine (VAN)
Usaf B-24
1,2-Dihydro-6-ethoxy-2,2,4-trimethylquinoline
6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinoline
Ethoxychin [Czech]
Santoflex
Antox
Caswell No. 427D
NSC-6795
1,2-Dihydro-2,2,4-trimethyl-6-ethoxyquinoline
6-ethoxy-2,2,4-trimethyl-1H-quinoline
2,2,4-Trimethyl-6-ethoxy-1,2-dihydroquinoline
CCRIS 2513
HSDB 400
SantoquinEQ
6-ETMDQ
EINECS 202-075-7
EMQ
EPA Pesticide Chemical Code 055501
UNII-9T1410R4OR
DTXSID9020582
CHEBI:77323
AI3-17715
9T1410R4OR
ETHOXYQUIN [MI]
ETHOXYQUIN [FCC]
ETHOXYQUIN [HSDB]
EQ
ETHOXYQUIN [MART.]
6-(ethyloxy)-2,2,4-trimethyl-1,2-dihydroquinoline
DTXCID70582
NSC 6795
Ethyl 2,2,4-trimethyl-1,2-dihydro-6-quinolinyl ether
CAS-91-53-2
NCGC00016348-02
E324
E 324
ETHOXYQUIN (MART.)
2,2, 4-Trimethyl-6-ethoxy-1,2-dihydroquinoline
6-Ethoxy-1, 2-dihydro-2,2,4-trimethylquinoline
6-Ethoxy-2,2,4-trimethyl-1, 2-dihydroquinoline
6-Ethoxy-1,2-dihydro-2,2,4-trimethyl-Quinoline
6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinoline, 9CI, 8CI
1,2-DIHYDRO-2,2,4-TRIMETHYLQUINOLIN-6-YL ETHYL ETHER
StopScald
NixScald
MFCD00023883
Prestwick_1064
RALUQUIN
Ethoxyquin (Standard)
Spectrum_001214
Prestwick0_000765
Prestwick1_000765
Prestwick2_000765
Prestwick3_000765
Spectrum2_001384
Spectrum3_001423
Spectrum4_000404
Spectrum5_001530
Pesticide Code 055501
SCHEMBL21601
BSPBio_000810
BSPBio_003126
KBioGR_000668
KBioSS_001694
MLS001055488
BIDD:GT0822
DivK1c_000183
SPECTRUM1500998
SPBio_001368
SPBio_002749
BPBio1_000892
CHEMBL172064
HMS500J05
HY-B1425R
KBio1_000183
KBio2_001694
KBio2_004262
KBio2_006830
KBio3_002346
NSC6795
NINDS_000183
HMS1570I12
HMS1923K03
HMS2097I12
HMS3714I12
1,2,4-trimethyl-6-ethoxyquinoline
HY-B1425
6-Ethoxy-1,2,4-trimethylquinoline
Tox21_110388
Tox21_201336
Tox21_300328
CCG-39002
Ethoxyquin, >=75% (capillary GC)
s5369
STK772149
AKOS000121441
CS-8200
FE22911
IDI1_000183
NCGC00016348-01
NCGC00016348-03
NCGC00016348-04
NCGC00016348-05
NCGC00016348-06
NCGC00016348-07
NCGC00016348-08
NCGC00016348-09
NCGC00016348-15
NCGC00090792-01
NCGC00090792-02
NCGC00090792-03
NCGC00090792-04
NCGC00090792-05
NCGC00254395-01
NCGC00258888-01
1,2Dihydro2,2,4trimethyl6ethoxyquinoline
1,2Dihydro6ethoxy2,2,4trimethylquinoline
2,2,4Trimethyl6ethoxy1,2dihydroquinoline
6Ethoxy1,2dihydro2,2,4trimethylquinoline
6Ethoxy2,2,4trimethyl1,2dihydroquinoline
AC-11742
AS-14741
SMR000686069
DB-057260
Ethoxyquin, Vetec(TM) reagent grade, 75%
WLN: T66 BM CHJ C1 C1 E1 HO2
E0237
NS00009586
Quinoline, 6ethoxy1,2dihydro2,2,4trimethyl
2,4-Trimethyl-6-ethoxy-1,2-dihydroquinoline
6-Ethoxy-2,4-trimethyl-1,2-dihydroquinoline
EN300-21213
Ethoxyquin, PESTANAL(R), analytical standard
F85585
SR-01000854319
Q1657816
SR-01000854319-2
1,2-dihydro-2,2,4-trimethyl-6-quinolyl ethyl ether
BRD-K56792340-001-05-8
BRD-K56792340-001-13-2
ethyl 2,2,4-trimethyl-1,2-dihydro-6-quinolyl ether
2,2,4-TRIMETHYL-1,2-DIHYDRO-6-ETHOXYQUINOLINE
Z104494382
A10AE280-05F4-4846-ACAE-D565B0D263A2
Ethyl 2,2,4-trimethyl-1,2-dihydro-6-quinolinyl ether #
6-Ethoxy-2,2,4-trimethyl-1,2-dihydroquinoline [Antioxidant for rubber]
202-075-7
6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinoline;1,2-Dihydro-2,2,4-trimethyl-6-ethoxyquinoline;1,2-Dihydro-6-ethoxy-2,2,4-trimethylquin oline