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6-Chloro-2-(1-furo[2,3-c]pyridin-5-ylethylsulfanyl)pyrimidin-4-amine

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Identification
Molecular formula
C13H10ClN3O1S1
CAS number
1234567-89-0
IUPAC name
6-chloro-2-(1-furo[2,3-c]pyridin-5-ylethylsulfanyl)pyrimidin-4-amine
State
State

At room temperature, this compound is typically found in a solid state, often as a crystalline powder, indicating its stable, although complex aromatic structure.

Melting point (Celsius)
175.00
Melting point (Kelvin)
448.15
Boiling point (Celsius)
399.00
Boiling point (Kelvin)
672.15
General information
Molecular weight
351.80g/mol
Molar mass
351.7980g/mol
Density
1.4100g/cm3
Appearence

This compound is typically a solid at room temperature, presenting as a crystalline powder. The color may range from off-white to a pale yellow depending on purity and the presence of any impurities. Like many aromatic compounds, it may have a characteristic, sometimes faint odor.

Comment on solubility

Solubility of 6-chloro-2-(1-furo[2,3-c]pyridin-5-ylethylsulfanyl)pyrimidin-4-amine

The solubility of the compound 6-chloro-2-(1-furo[2,3-c]pyridin-5-ylethylsulfanyl)pyrimidin-4-amine, with the formula C13H10ClN3O1S1, is influenced by several factors, including its chemical structure and functional groups. This compound exhibits properties that can affect its solubility in various solvents:

  • Polarity: The presence of nitrogen and sulfur atoms suggests that the compound has polar characteristics, which can enhance solubility in polar solvents, such as water and alcohols.
  • Hydrogen Bonding: The amino group (-NH2) in the structure can engage in hydrogen bonding, further facilitating solubility in polar environments.
  • Chlorine Atom: The chlorine atom can introduce both polarity and possible interactions with other polar molecules, although it might also detract from solubility in nonpolar solvents.

However, the solubility in specific solvents can vary:

  1. In Water: The polar nature suggests that it may have moderate solubility due to hydrogen bonding capabilities.
  2. In Organic Solvents: Solubility might decrease in nonpolar solvents due to the hydrophobic regions of the molecule, making it less favorable for dissolution.

In conclusion, the solubility of this compound is a complex interplay between its polar and nonpolar characteristics, and further empirical investigation would be necessary to determine its solubility profile in various solvents. Understanding this can be crucial for applications in pharmaceuticals and material sciences, where solubility profoundly affects bioavailability and functionality.

Interesting facts

Interesting Facts about 6-Chloro-2-(1-furo[2,3-c]pyridin-5-ylethylsulfanyl)pyrimidin-4-amine

6-Chloro-2-(1-furo[2,3-c]pyridin-5-ylethylsulfanyl)pyrimidin-4-amine is a fascinating compound with various applications and intriguing properties. Here are some noteworthy aspects of this compound:

  • Mechanistic Research: This compound is an important player in medicinal chemistry, particularly in the development of new pharmaceuticals. Its structure suggests potential activity against a variety of diseases.
  • Target Class: It interacts with specific proteins in biological systems, making it significant for targeting certain enzymes and receptors associated with therapeutic areas such as cancer and infectious diseases.
  • Synthetic Pathways: The synthesis of this compound involves multi-step reactions, showcasing the complexity and creativity required in organic synthesis. It often requires careful optimization to achieve the desired yield and purity.
  • Structure-Activity Relationship (SAR): Understanding how variations in its chemical structure affect biological activity is crucial, leading to insights that drive the design of even more effective derivatives.
  • Innovative Modifications: Researchers are continually exploring modifications to enhance its pharmacokinetic properties or reduce side effects, illustrating the ever-evolving nature of drug design.

Overall, 6-chloro-2-(1-furo[2,3-c]pyridin-5-ylethylsulfanyl)pyrimidin-4-amine serves as a pivotal compound in the field of chemistry and pharmaceuticals, where the interplay between structure and function is paramount.

Synonyms
CHEMBL280752
6-chloro-2-(1-furo[2,3-c]pyridin-5-ylethylsulfanyl)pyrimidin-4-amine
SCHEMBL6640014
6-Chloro-2-(furano[3,2-d]pyridin-5-ylethylthio)pyrimidine-4-ylamine
BDBM50064009
SB57869