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6-Chloropurine

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Identification
Molecular formula
C5H3ClN4
CAS number
87-42-3
IUPAC name
6-chloro-1H-purine
State
State

At room temperature, 6-chloropurine exists as a solid.

Melting point (Celsius)
275.00
Melting point (Kelvin)
548.15
Boiling point (Celsius)
332.00
Boiling point (Kelvin)
605.15
General information
Molecular weight
155.56g/mol
Molar mass
155.5580g/mol
Density
1.8200g/cm3
Appearence

The compound appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 6-Chloro-1H-purine

6-Chloro-1H-purine, a purine derivative, presents interesting characteristics regarding its solubility. This compound is known to exhibit limited solubility in water, making it crucial to consider its behavior in various solvents.

Here are some key points regarding its solubility:

  • Water Solubility: 6-Chloro-1H-purine generally has a low solubility in aqueous solutions, which can affect its availability in biological systems.
  • Organic Solvents: It tends to dissolve more readily in organic solvents, such as dimethyl sulfoxide (DMSO) and ethanol, highlighting its compatibility with non-polar environments.
  • Temperature Influence: The solubility may increase with temperature, influencing the solubility dynamics in practical applications.
  • pH Dependency: The presence of functional groups in the solvent can also affect the solubility behavior; for instance, acidic or basic conditions could alter the ionization state of the 6-chloro-1H-purine.

In summary, while 6-chloro-1H-purine holds promise for various applications, its solubility characteristics necessitate careful consideration in formulation and use. Understanding these properties can lead to better outcomes in both laboratory and industrial settings.

Interesting facts

Interesting Facts about 6-Chloro-1H-Purine

6-Chloro-1H-purine is a fascinating compound that belongs to the purine family, which are essential biological molecules. Here are some interesting aspects of this compound:

  • Structural Significance: As a derivative of purine, a fundamental building block of DNA and RNA, 6-chloro-1H-purine plays an essential role in the study of nucleic acids.
  • Pharmaceutical Applications: This compound has garnered attention in medicinal chemistry for its potential as an inhibitor in various biochemical pathways, making it a candidate for drug development.
  • Chlorine Substitution: The presence of chlorine at the 6-position of the purine ring introduces unique chemical properties that can affect the compound's reactivity and biological activity.
  • Biosynthesis Research: It is often studied in the context of purine metabolism, offering insights into how organisms synthesize nucleotides and related compounds.
  • Research Interest: Numerous studies explore its role in promoting cell signaling, and it has been linked to various cellular processes, including cell division and growth.

Researchers often quote, "Understanding the nuances of compounds like 6-chloro-1H-purine opens doors to revolutionary advances in biochemistry and pharmaceuticals." This reflects the compound's significance in the ongoing quest for novel therapeutic agents.

In summary, 6-chloro-1H-purine represents a bridge between foundational biology and cutting-edge medicinal research. The study of this compound can yield valuable insights that advance both the fields of chemistry and medicine.