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6-Chloro-1,2-benzisothiazol-3-one

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Identification
Molecular formula
C7H4ClNO2S
CAS number
26117-28-2
IUPAC name
6-chloro-1,2-benzothiazol-3-one
State
State

At room temperature, 6-Chloro-1,2-benzisothiazol-3-one is in a solid state. It is often found in the form of crystalline powder, making it relatively easy to handle and apply in various settings.

Melting point (Celsius)
155.00
Melting point (Kelvin)
428.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
185.62g/mol
Molar mass
185.6220g/mol
Density
1.5480g/cm3
Appearence

6-Chloro-1,2-benzisothiazol-3-one appears as a crystalline solid with a white to pale yellow color. It is typically provided in powder form and remains stable under normal conditions.

Comment on solubility

Solubility of 6-chloro-1,2-benzothiazol-3-one

The solubility of 6-chloro-1,2-benzothiazol-3-one (C7H4ClNO2S) is an important characteristic that influences its applications in various fields, including pharmacology and material sciences. This compound exhibits a unique solubility profile due to its intricate molecular structure, characterized by the presence of both polar and nonpolar functional groups.

Solubility Properties:

  • Polar Solvents: 6-chloro-1,2-benzothiazol-3-one tends to be soluble in polar solvents like dimethyl sulfoxide (DMSO) and methanol, owing to its polar carbonyl and nitrogen functionalities.
  • Nonpolar Solvents: Conversely, it shows limited solubility in nonpolar solvents such as hexane and toluene, due to the hydrophobic nature of the aromatic ring.
  • Temperature Dependence: The solubility can also be affected by temperature; increasing the temperature typically enhances the solubility of such organic compounds.

Moreover, it is crucial to consider the implications of solubility on the compound's reactivity and bioavailability. As the saying goes, "like dissolves like," implying that the solvation interactions are significant for understanding how this compound behaves in various environments. Additionally, the pH of the solution can influence its solubility, as ionization of functional groups may occur, altering the overall solubility characteristics.

In summary, 6-chloro-1,2-benzothiazol-3-one exemplifies a compound where the **balance between hydrophilicity and hydrophobicity** plays a critical role in determining its solubility in different solvent systems.

Interesting facts

Interesting Facts about 6-chloro-1,2-benzothiazol-3-one

6-chloro-1,2-benzothiazol-3-one is a fascinating compound that belongs to the class of benzothiazoles, which are known for their diverse applications in various fields. Here are some intriguing details about this compound:

  • Structural Features: The compound features a benzothiazole ring, which is a fused bicyclic structure containing both sulfur and nitrogen. This unique arrangement contributes to its chemical reactivity and versatility.
  • Biological Activity: Compounds like 6-chloro-1,2-benzothiazol-3-one often exhibit notable biological properties. They have been studied for their potential antibacterial, antifungal, and anticancer activities, making them of particular interest in medicinal chemistry.
  • Industrial Applications: This compound is sometimes used in the production of dyes and pigments. Its vibrant color properties render it valuable in the textile industry, where color fastness and stability are crucial.
  • Synthetic Utility: In organic synthesis, benzothiazole derivatives, including 6-chloro-1,2-benzothiazol-3-one, serve as building blocks for creating more complex molecules. Their ability to undergo various chemical transformations makes them essential reagents in the laboratory.
  • Environmental Considerations: As with many chemical compounds, it's important to consider the environmental implications of 6-chloro-1,2-benzothiazol-3-one. Regulation and safe handling of materials containing chlorine are crucial to prevent adverse ecological effects.

In the world of chemical research, 6-chloro-1,2-benzothiazol-3-one stands out due to its unique properties and potential applications. As scientists and students alike continue to explore its characteristics, more applications and discoveries may yet be revealed. As noted by researchers, "The exploration of benzothiazoles opens a pathway to unlocking new therapeutic agents."

Synonyms
TICLATONE
70-10-0
6-Chlorobenzo[d]isothiazol-3(2H)-one
6-CHLORO-1,2-BENZISOTHIAZOL-3(2H)-ONE
Ticlatona
6-chloro-1,2-benzothiazol-3-one
FER-1443
1,2-Benzisothiazol-3(2H)-one, 6-chloro-
6-Chloro-1,2-benzisothiazolin-3-one
6-Chlorobenzo[d]isothiazol-3-ol
6-chloro-2,3-dihydro-1,2-benzothiazol-3-one
BHW384Q9GI
DTXSID8057809
Landromil
Ticlatonum
Ticlatone [USAN:INN]
Ticlatonum [INN-Latin]
Ticlatona [INN-Spanish]
6-chlorobenzo[d]isothiazol-3[2H]-one
6-Chloro-1,2-benzisothiazolone
UNII-BHW384Q9GI
1,2-Benzisothiazolin-3-one, 6-chloro-
TICLATONE [INN]
Ticlatone (USAN/INN)
TICLATONE [USAN]
TICLATONE [WHO-DD]
SCHEMBL193888
CHEMBL2103914
DTXCID6031598
CHEBI:136026
6-chloro-benzo[d]isothiazol-3-one
Tox21_113906
MFCD00865021
AKOS006272013
DB13613
CAS-70-10-0
NCGC00262908-01
MS-22998
SY212101
DB-359510
HY-138136
CS-0145451
NS00124439
D06139
EN300-365814
F51296
Q7800731
Z1198155415